Isomers Skincare Laboratories 5% Argireline Amplified Peptide Booster Serum Versus Cos De BAHA P M.A Peptide Serum
This anti-aging serum is formulated around Sodium Hyaluronate and Acetyl Hexapeptide-8 to soften the look of wrinkles and hydrate skin.
This anti-aging serum is formulated around Niacinamide and Palmitoyl Tripeptide-1 to soften the look of wrinkles and refine skin texture.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Aloe Barbadensis Leaf Extract
Emollient
Propanediol
Solvent
Glycerin
Humectant
Niacinamide
Smoothing
1,2-Hexanediol
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Acetyl Hexapeptide-8
Humectant
Panthenol
Skin Conditioning
Sodium Hyaluronate
Humectant
Beta-Glucan
Skin Conditioning
Adenosine
Skin Conditioning
Allantoin
Skin Conditioning
Butylene Glycol
Humectant
Carbomer
Emulsion StabilisingPolysorbate 20
Emulsifying
Caprylyl Glycol
Emollient
Sodium Lactate
Buffering
Water
Skin ConditioningRosa Damascena Extract
MaskingLavandula Angustifolia Flower Extract
Cleansing
Camellia Sinensis Leaf Extract
Antimicrobial
Melissa Officinalis Leaf Extract
Skin ConditioningArtemisia Vulgaris Extract
Skin Conditioning
Aloe Barbadensis Leaf Extract, Propanediol, Glycerin, Niacinamide, 1,2-Hexanediol, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Acetyl Hexapeptide-8, Panthenol, Sodium Hyaluronate, Beta-Glucan, Adenosine, Allantoin, Butylene Glycol, Carbomer, Polysorbate 20, Caprylyl Glycol, Sodium Lactate, Water, Rosa Damascena Extract, Lavandula Angustifolia Flower Extract, Camellia Sinensis Leaf Extract, Melissa Officinalis Leaf Extract, Artemisia Vulgaris Extract
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".
It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.
The comparison to Botox does have limits because the molecule is water-loving and relatively large.
Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.
So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.
A 12 week human study of a multi-ingredient regimen containing this ingredient saw:
While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).
Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.
Learn more about Acetyl Hexapeptide-8Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.
Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.
Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.
It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.
Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.
This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.
Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.
Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.
Learn more about AllantoinAloe Barbadensis Leaf Extract is a botanical extract pulled from the leaves of aloe vera and one of the most studied plant ingredients in cosmetics.
The inner leaf gel it comes from is mostly water (~99-99.5%) and the remaining fraction is made up of pretty good stuff: polysaccharides, vitamins, phenolics, and enzymes.
Its headline job is hydration.
The star polysaccharide in aloe, acemannan, is a humectant that retains moisture and helps reduce trans-epidermal water loss.
Aloe also has real soothing credentials; it contains anti-inflammatory compounds like bradykinase and C-glucosyl chromone that help calm irritation and redness.
On the repair side, lab work shows that acemannan wakes up your skin's repair cells (fibroblasts), prompting them to multiply and speed up healing.
There's some human data for cosmetic benefit too: a cream containing 10% Aloe Barbadensis leaf extract improved skin hydration and elasticity in a real-use study.
Safety-wise, this ingredient is well-regarded with just one rare downside; there have been some case reports of acute eczema, contact urticaria, and dermatitis in people who applied aloe-derived ingredients topically. Those with a known aloe or Liliaceae sensitivity should patch test.
Typical use levels range widely, from under 1% up to 90%+ depending on the format and the effect you are after.
Learn more about Aloe Barbadensis Leaf ExtractSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water
