Skin Functional 2% Acnoclear Complex

Skin Functional 2% Acnoclear Complex

This acne serum is formulated around Mandelic Acid and Sodium Ascorbyl Phosphate to clear breakouts and refine the look of pores.

Worth noting

Contains a retinoid, which is best introduced gradually.

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What's inside

Key Ingredients

Benefits

Concerns

Ingredients Explained

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Learn more about Water
Skin Conditioning

Aloe Barbadensis Leaf Juice is the filtered, stabilized liquid pressed from the inner gel of the aloe vera leaf.

In cosmetics, it shows up as either soothing active or a water-replacement base. It is roughly 98-99% water and the last 1-2% is an interesting mix of polysaccharides, amino acids, vitamins, minerals, and enzymes.

The polysaccharides do most of the work: they bind water at the skin surface for a light, non-greasy hydration boost. And one of the polysaccharides, glycomannan, is linked to fibroblast stimulation + collagen synthesis. This is also why aloe has such a long track record in wound and burn healing.

This ingredient is also calming with anti-inflammatory and mild antimicrobial activity, making it a great pick for sensitive, irritated, or post-sun skin.

Realistic expectations matter though; the solid evidence is mostly limited to hydration, soothing, and wound support. Deeper claims about anti-aging or sun protection are not well backed, and science reviews note it does not prevent radiation-induced skin injury.

Because it plays well with almost everything, it's commonly used as a base alongside other actives like niacinamide or vitamin C.

Typical usage concentrations range from 0.5% (where hydration benefits already show up) all the way to 90%+ (where it replaces water as the main base).

The safety for this ingredient is well-establish as well. Overall, this is a great supporting ingredient for those who want a boost in hydration.

Learn more about Aloe Barbadensis Leaf Juice
Antimicrobial

Mandelic Acid is an alpha hydroxy acid (AHA).

Like other AHAs, it helps exfoliate the surface of the skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

Mandelic acid helps with:

Due to it having a larger molecular size than glycolic acid, mandelic acid is able to penetrate the skin more slowly and evenly. This makes it gentler and less irritating, making it a great option for sensitive or beginner skin.

Despite being milder, mandelic acid is still an effective exfoliant that improves skin texture and tone over time.

What makes mandelic acid stand out from other AHAs? It has antibacterial and antioxidant properties.

These traits make it a great option for acne-prone or problem skin by reducing active breakouts and fading post-acne marks. Studies show that mandelic acid (especially when combined with salicylic acid) can significantly reduce pimples and hyperpigmentation while causing fewer side effects than stronger acids.

Mandelic acid is effective in concentrations of 5% and up with an ideal pH range of 3-4 for at-home use.

Like other AHAs, it’s important to wear sunscreen daily to protect your newly exfoliated skin.

However, unlike glycolic acid, mandelic acid is light-sensitive. Be sure your mandelic acid is packaged in opaque containers to ensure it stays stable and effective.

In short, mandelic acid is a gentle yet powerful AHA that exfoliates, brightens, and helps clarify skin while keeping irritation low. Its antibacterial action makes it especially beneficial for those with acne-prone, sensitive, or uneven skin, offering smoother, clearer, and more even-toned results over time.

Read more about some other popular AHA's here:

Learn more about Mandelic Acid
Skin Conditioning

Retinyl Palmitate is a form of retinoid. Retinoids are the superstar class of anti-aging ingredients that include Tretinoin and Retinol.

This particular ingredient has had a bumpy year with its rise and fall in popularity.

First, Retinyl Palmitate is created from Palmitic Acid and Retinol. It is a Retinol ester and considered one of the weaker forms of retinoid.

This is because all retinoids have to be converted to Tretinoin, AKA Retinoic Acid.

Retinyl Palmitate is pretty far down the line and has to go through multiple conversions before its effects are seen. Once it's on your skin, enzymes called esterases convert it into Retinol, then into Retinal, and finally into Retinoic Acid; that's three steps with a little lost at each one.

The benefits of Retinyl Palmitate are debated due to this long and ineffective conversion line.

So why use it at all?

The answer is stability. Retinol and Retinoic Acid break down fast when they hit light, heat, and air, and Retinoic Acid can be pretty irritating on top of that.

Retinyl Palmitate is much more stable and gentler, making it easier to formulate with and easier on sensitive skin (even if it's weaker gram for gram).

Studies show Retinyl Palmitate to help:

Newer research from 2023-2025 also found that Retinyl Palmitate works especially well when paired with Retinol. The two seem to cover each other's weak spots; retinol brings the potency while Retinyl Palmitate brings the stability and gentleness. Together, they repair UV damage better than either one does alone.

This ingredient used to be found in sunscreens to boost the efficacy of sunscreen filters.

The downfall of Retinyl Palmitate was due to released reports about the ingredient being correlated to sun damage and skin tumors.

Most of this traces back to a 2012 US National Toxicology Program (NTP) study where hairless mice coated in Retinyl Palmitate cream and exposed to UV light developed skin tumors faster.

Here's the nuance, though.

When the Cosmetic Ingredient Review (CIR) Expert Panel went back through that study, they found methodological flaws and decided the results couldn't be interpreted as proof of extra risk.

The EU's Scientific Committee on Consumer Safety (SCCS) said the mouse findings might point to a concern but they're hard to apply to humans since hairless mouse skin and human skin behave differently.

While there is a study showing this ingredient to cause DNA damage when exposed to UVA, there is no concrete proof of it being linked to skin cancer. It is completely safe to use when used correctly.

Both the CIR and the SCCS consider it safe at the concentrations used in cosmetics; the SCCS specifically cleared retinoids up to 0.05% in body lotions and 0.3% in face creams, hand creams, and rinse-off products.

As of 2025, the EU has written those limits into law, plus a label warning about your total Vitamin A intake from all sources.

All retinoids increase your skin's sensitivity to the sun in the first few months of usage. Be especially careful with reapplying sunscreen when using any form of retinoid.

One more note: if you're pregnant, high doses of Vitamin A can be a concern, so a lot of people skip topical retinoids (including Retinyl Palmitate) during pregnancy just to be safe. Check with your doctor if you're unsure.

Fun fact: This ingredient is often added to low-fat milk to increase the levels of Vitamin A.

Learn more about Retinyl Palmitate

Sodium Ascorbyl Phosphate (SAP) is a water-soluble form of Vitamin C. It is the salt of ascorbic acid.

This ingredient is commonly used in skincare because it's more formulation-stable while still offering the same benefits as pure ascorbic acid. Ascorbic acid is notorious for breaking down when exposed to sunlight and oxygen whereas SAP has been shown to be more stable.

Studies show SAP has anti-acne and antioxidant benefits. One study found 5% of SAP lotion to be an effective ingredient for treating acne vulgaris. This is because research shows that SAP may help control acne by reducing acne-causing bacteria and slowing the oxidation of skin oils caused by UV exposure.

In addition to acne, vitamin C is important for skin structure. Lab studies suggest SAP may support collagen production in skin cells, making it a great ingredient in anti-aging routines.

Vitamin C has many benefits: it helps reduce redness, improve skin texture, fade the appearance of dark spots, and brighten the skin.

Read more about other types of Vitamin C:

Learn more about Sodium Ascorbyl Phosphate
Humectant, Skin Conditioning

Betaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. It’s known for being gentle and for helping the skin maintain balanced hydration.

Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.

Some studies suggest betaine may support making skin tone more even.

Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.

Betaine is also known as trimethylglycine.

Learn more about Betaine
Humectant, Skin Conditioning, Skin Protecting

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin

Benzoyl Peroxide (BPO) is one of the most studied and widely used acne-fighting ingredients on the market for over five decades.

It works by releasing oxygen into your pores to kill Cutibacterium acne, or the bacteria closely linked to acne breakouts. This bacteria has a hard time surviving in an oxygen-rich environment.

On top of that, BPO has keratolytic properties to help shed dead skin cells and keep pores from getting clogged.

One of the coolest things about BPO is that bacteria do not develop resistance to it the way they can with antibiotics. That's why dermatologists recommend pairing it with topical antibiotics to keep resistance at bay.

BPO is usually available in 2.5%, 5%, and 10% concentrations. Research has shown that 2.5% tends to be just as effective as the higher strengths while being more gentle on the skin.

The FDA has classified BPO as a safe and effective acne treatment. You'll be able to find this ingredient in over-the-counter products in many countries.

Just so you know, BPO is a known mild irritant. It's common to see dryness, peeling, and some redness when you first start using it. This usually goes away as your skin adjusts.

A very small number of people might develop allergic contact dermatitis from it as patch test studies show positive reactions in about 1-5% of patients.

Once BPO is absorbed into the skin, our bodies turn it into benzoic acid and quickly exits in urine. It's also worth noting that BPO will bleach fabrics and hair, so watch your towels and pillowcases!

Learn more about Benzoyl Peroxide
Skin Conditioning

Glycyrrhetinic acid is a compound found in licorice. It has skin conditioning, skin soothing, antibacterial, and antioxidant properties.

Not only is this a great ingredient for soothing inflammation, studies show this compound is effective at protecting skin against UV-B induced damage.

Fun fact: This ingredient is also used to mask the bitter taste of medicine.

Learn more about Glycyrrhetinic Acid
Skin Conditioning, Skin Protecting, Soothing

Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics.

Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.

Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation.

It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh.

Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated.

This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%.

Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating.

Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism.

Learn more about Allantoin
Antioxidant, Masking, Skin Conditioning

Bisabolol is a gentle skin conditioner, antioxidant, and soothing ingredient.

It's primary claim to fame is soothing and research shows topically applied bisabolol can quiet the chemical messengers that cause your skin to become inflamed, helping to sooth any irritation.

A clinical study found that applying 0.5% bisabolol daily for 8 weeks produced an average 9% decrease in skin pigmentation. Researchers found it can also suppress the process that leads to excess melanin production in skin.

In vitro studies found that bisabolol combined with propylene glycol significantly increased skin permeability by increasing lipid fluidity in the stratum corneum.

You'll likely see use concentrations quite low, usually 0.1-0.2%.

Overall, this is a well-tolerated ingredient that works well in formulas designed for sensitive, reactive, or post-procedure skin.

Learn more about Bisabolol
Emollient, Skin Conditioning

We don't have a description for Hydrogenated Ethylhexyl Olivate yet.

Emulsion Stabilising

Polyacrylate Crosspolymer-6 is a texture enhancer and pH adjuster.

It is be used to thicken water-based products and create a gel-texture with a velvet feel.

One manufacturer claims this ingredient to have a pH range of 2-8 and to be biodegradable.

This ingredient is also known as Sepimax Zen.

Learn more about Polyacrylate Crosspolymer-6

Passiflora Edulis Seed Oil is a lightweight plant oil from the seeds of passion fruit.

This oil supports skin hydration because it is packed with linoleic acid (56-73%), oleic acid (14-20%), palmitic acid, and stearic acids. It also contains vitamin E and other antioxidants, like carotenoids.

In vitro research has shown that passion fruit seed extracts can inhibit the enzymes that break down collagen and elastin in the skin.

While this ingredient is considered well-tolerated, some cases of contact dermatitis have been reported with the Passiflora plant's vines and leaves itself. As with any ingredient, a patch test is a great idea if you are unsure.

This may not be suitable for fungal acne-prone skin due to the fatty acid content.

Learn more about Passiflora Edulis Seed Oil

Ribes Nigrum Seed Oil is oil from the seeds of Black Currant. A more common name for this ingredient is Black Currant Seed Oil.

Black Currant Seed Oil contains a high amount of omega-6 and omega-3 fatty acids. It also contains linoleic acid.

Black currant berries contain anthocyanins, an antioxidant. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.

Black currant berries also contain Vitamin E and fatty acids. It can help soften the skin.

Learn more about Ribes Nigrum Seed Oil
Skin Conditioning

Phospholipids are a family of skin-identical lipids that makeup the structural backbone of every cell membrane in your body.

In cosmetics, they function as skin conditioning agents with emulsifier and surfactant properties. They're typically sourced from soybean or sunflower lecithin (or sometimes egg yolk or marine sources).

Because they mirror the lipids naturally found in the deeper layers of your skin, topical phospholipids help reinforce the lipid matrix, reduce transepidermal water loss, and leave skin feeling conditioned.

They're also used to form liposomes, or tiny self-assembling vesible used to stabilize actives like vitamin c or retinol. This helps these ingredients integrate into the upper layers of skin more easily.

Phospholipids are compatible with everything and the CIR Expert Panel has concluded them to be safe at current use levels.

Some types of phospholipids include:

Learn more about Phospholipids
Antioxidant, Humectant, Skin Conditioning

Tremella Fuciformis is also known as snow mushroom. This ingredient comes from the sporocarp, which is also the fruit body of the fungi.

Snow mushroom has hydrating and antioxidant properties.

According to a manufacturer, the glucuronic acid of this ingredient promotes the presence of hyaluronic acid in the middle layer of skin to keep that layer sufficiently hydrated.

Learn more about Tremella Fuciformis Sporocarp Extract
Skin Conditioning

Docosahexaenoic Acid isn't fungal acne safe.

Emollient, Skin Conditioning

Eicosapentaenoic Acid isn't fungal acne safe.

Skin Conditioning

Phytosterols are plant-derived sterols (you can think of them as the plant world's version of cholesterol). In cosmetics, this ingredient is usually sourced from soybean, rice bran, shea, sunflower, and other seed oils.

The main actors in this group are β-sitosterol, campesterol, and stigmasterol (the CIR covers 27 phytosterols).

They work by fitting perfectly into your stratum corneum's lipid matrix since they're structurally similar to cholesterol. Here, they reinforce your skin's barrier.

One small in vivo human study showed topical soybean phytosterols sped up barrier recovery within three days on tape-stripped skin.

Broader research credits them with:

Formulation use typically sit under 5%.

Testing in soy-allergic subjects found no sensitization signals, but be sure to patch test if you are unsure or have existing allergies.

Learn more about Phytosterols
Preservative

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Learn more about Phenoxyethanol
Skin Conditioning

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Learn more about Ethylhexylglycerin

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Where it's from

Skin Functional is a South African brand

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· Updated December 9, 2025