Prescription
Prescription
American United States
Swiss Switzerland

What's inside

What's inside

Key Ingredients

Benefits

Concerns

Reviews

5.00
Overall rating
5
4
3
2
1
What people say
Drying 100% Great Value 100% Irritating 100%
No reviews yet

Be the first to review

Write the first review

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

BHT
Antioxidant, Masking

BHT is a synthetic antioxidant and preservative.

As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.

As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.

The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.

However, it was recently restricted for use in the UK as of April 2024.

Learn more about BHT
Emollient, Emulsifying, Emulsion Stabilising

Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.

Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.

It plays several roles in a formula:

Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.

Multiple assessments have found it to be non-irritating and non-sensitizing to most people.

However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.

Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.

Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.

Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.

This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.

A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.

Learn more about Cetearyl Alcohol
Emulsifying, Surfactant

Polysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.

Polysorbate 60 is sorbitol-based and created from the ethoxylation of sorbitan. Ethoxylation is a chemical reaction used to add ethylene oxide. Sorbitan is a the dehydrated version of sorbitol, a sugar found in fruits.

In this case, the 60 comes from reacting 60 units of ethylene oxide with sorbitan.

Polysorbates are commonly used in medicine and foods.

Learn more about Polysorbate 60
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Learn more about Water
Skin Conditioning

Tretinoin (aka retinoic acid) is the gold standard retinoid in dermatology because it's the form of vitamin A that your skin can use right away. It's a prescription drug and regulated as medication in most countries.

Unlike retinol, it skips the conversion steps and goes straight to work.

Inside your skin cells, it binds to receptors called retinoic acid receptors and switches on the genes that control how skin cells behave.

For acne, it helps your skin shed dead cells properly instead of letting them build up and clog your pores (this is what turns into blackheads and pimples). It also calms redness/swelling, which is why it's a FDA-approved acne treatment.

Tretinoin also tells your skin to make more collagen and slows down the stuff that breaks collagen apart too. Over time, your skin looks smoother, softer, and more even, with fewer lines lines and sun spots.

The evidence for this ingredient is strong:

A systematic review of randomized controlled trials found that topical tretinoin consistently improved wrinkles, pigmentation, sallowness, and dark spots. Results typically showed up as early as one month and lasted out to 24 months.

All studies also found this ingredient to be safe and well-tolerated.

Typical concentrations run from about 0.01-0.1%, with 0.025%-0.1% being the usual range studied for photoaging and a 0.05% cream producing measurable wrinkle/roughness improvements in large six-month trials.

The main trade-off is irritation; dryness, peeling, redness, and sun sensitivity are common in the first few weeks so be sure to pair it well with a good moisturizer and daily sunscreen.

Learn about a form of retinoid you can purchase at the store, retinol.

Learn more about Tretinoin

Similar Comparisons