Explore Routine Login
Versus

Neutrogena Rapid Wrinkle Repair Serum Versus Differin Adapalene Gel 0.1% Acne Treatment

Serum
Facial Treatment
American Brand United States
American Brand United States

Updated on May 16, 2024

Overview

Cool Features

They both contain retinoid

Suited For

They're both likely to be good for fighting acne and anti aging

Free From

They both do not contain any harsh alcohols, common allergens, oils or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Concerns

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Rapid Wrinkle Repair Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Dimethicone Emollient, Skin Conditioning, Skin Protecting
1 / 0 Silicon Icon
SiliconSilicon Icon

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

1 Com. / 0 Irr.
Very Disliked Full details ->
Aluminum Starch Octenylsuccinate Absorbent

Aluminum Starch Octenylsuccinate is a synthetic powder used as an absorbent, thickener, and anti-caking agent.

Disliked Full details ->
Dimethicone Crosspolymer Emulsion Stabilising

Dimethicone Crosspolymer is a silicone created by modifying dimethicone with hydrocarbon side chains. Due to its large size, it does not penetrate skin. It is considered non-occlusive.

Very Disliked Full details ->
Ammonium Acryloyldimethyltaurate/Vp Copolymer

Ammonium Acryloyldimethyltaurate/Vp Copolymer (let's call it AAVC for short) is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.

Disliked Full details ->
Trisiloxane Skin Conditioning
Silicon Icon
SiliconSilicon Icon

Trisiloxane is a type of silicone.

Disliked Full details ->
Nylon-12
Non-Reef-Safe Icon
Non-Reef-SafeNon-Reef-Safe Icon

Nylon-12 is a polymer. It is derived from 12-aminododecanoic acid, an omega-amino fatty acid

Very Disliked Full details ->
C12-15 Alkyl Benzoate Antimicrobial, Emollient, Skin Conditioning

C12-15 Alkyl Benzoate is made up of Benzoic Acid and long chain alcohols. It has a low molecular weight.

Disliked Full details ->
Ascorbyl Glucoside Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon
Vitamin CVitamin C Icon AntioxidantAntioxidant Icon 6 Benefits

Ascorbyl Glucoside is a stable form of Vitamin C. It is created by combining glucose from starch.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Polyacrylamide

Polyacrylamide is a synthetic polymer. It is used to stabilize products and bind ingredients. When hydrated, Polyacrylamide forms a soft gel.

Disliked Full details ->
Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Parfum Masking, Perfuming
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon
FragranceFragrance Icon 2 Concerns

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Very Disliked Full details ->
C13-14 Isoparaffin Emollient, Solvent
May worsen Oily Skin IconNot safe for Fungal Acne Icon
2 Concerns

C13-14 Isoparaffin is created from petroleum-based mineral oils. It is an emollient and helps thicken a product.

Very Disliked Full details ->
Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Sodium Lactate Buffering, Humectant

Sodium Lactate is the sodium salt of lactic acid, an AHA. It is a humectant and used to adjust the pH of a product.

Hydrolyzed Myrtus Communis Leaf Extract Skin Protecting

We don't have a description for Hydrolyzed Myrtus Communis Leaf Extract.

Unknown Full details ->
Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

BHT Antioxidant, Masking
Antioxidant Icon
AntioxidantAntioxidant Icon

BHT is a synthetic antioxidant. As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.

Very Disliked Full details ->
Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Polysorbate 20 Emulsifying
0 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

0 Com. / 0 Irr.
Very Disliked Full details ->
Laureth-7 Emulsifying

Laureth-7 is created by the ethoxylation of lauryl alcohol using ethylene oxide. Lauryl alcohol is a fatty alcohol with hydrating properties.

Disliked Full details ->
Retinol Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconCan worsen Dry Skin IconMay cause irritation IconMay worsen Eczema Icon
RetinoidRetinoid Icon 8 Benefits 3 Concerns

Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.

Sodium PCA Humectant, Skin Conditioning
0 / 0

Sodium PCA is the sodium salt of pyroglutamic acid and is naturally occurring on human skin.

0 Com. / 0 Irr.
Sorbitol Humectant, Masking, Skin Conditioning
0 / 0 Helps hydrate Dry Skin Icon
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon

Sorbitol is a sugar alcohol. It is a hydrating and moisturizing agent created from the reduction process of glucose.

0 Com. / 0 Irr.
Proline Skin Conditioning

Proline is an amino-acid. It helps moisturize the skin and plays an important role in creating proteins.

Hinokitiol

We don't have a description for Hinokitiol.

Unknown Full details ->
Mica Cosmetic Colorant
May worsen Eczema Icon
May worsen EczemaMay worsen Eczema Icon

Mica refers to a group of silicate minerals. Mica crystals are easily split to give products a shimmer. These crystals are able to reflect light to temporarily give your skin a glowy look.

Very Disliked Full details ->
Titanium Dioxide Cosmetic Colorant, UV Absorber, UV Filter
0 / 0 Mineral UV Filter IconNon-Reef-Safe Icon
Mineral UV FilterMineral UV Filter Icon Non-Reef-SafeNon-Reef-Safe Icon

Titanium dioxide is known for its UVA and UVB protection properties. It is non-comedogenic and non-irritating. Titanium Dioxide is a physical sunscreen. Physical sunscreens reflect light and prevent it from reaching your skin.

0 Com. / 0 Irr.
Adapalene Gel 0.1% Acne Treatment
Adapalene
Retinoid IconHelps with Anti-Aging IconHelps fight Acne IconMay cause irritation IconMay worsen Rosacea Icon
RetinoidRetinoid Icon 2 Benefits 2 Concerns

Adapalene is a type of retinoid and common acne treatment.

Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Methylparaben Preservative
0 / 0 Preservative IconParaben IconNon-Reef-Safe IconMay worsen Eczema Icon
PreservativePreservative Icon ParabenParaben Icon 2 Concerns

Methylparaben is a preservative and is a paraben. It is used to prevent the growth of fungus, mold, and other harmful bacteria. Parabens are chemicals used as preservatives in both cosmetics and food.

0 Com. / 0 Irr.
Very Disliked Full details ->
Poloxamer 182 Emulsifying

We don't have a description for Poloxamer 182.

Unknown Full details ->
Propylene Glycol Humectant, Skin Conditioning, Solvent
0 / 0 May worsen Eczema Icon
May worsen EczemaMay worsen Eczema Icon

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

0 Com. / 0 Irr.
Disliked Full details ->
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Buffering
Mixed

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Learn more about Sodium Hydroxide
Disliked

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA

Ingredient Ratings

Here's what our community thinks of the ingredients in these products.

Rapid Wrinkle Repair Serum
10
2
16
2
liked
mixed
disliked
not rated
Adapalene Gel 0.1% Acne Treatment
2
1
4
1
liked
mixed
disliked
not rated

When to use

11 Routines
27% use in am
73% use in pm
100% use every day
1,869 Routines
8% use in am
92% use in pm
75% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Neutrogena Rapid Wrinkle Repair Serum 30 ingredients

Rapid Wrinkle Repair Serum hasn't been rated yet.
Rate it now

Differin Adapalene Gel 0.1% Acne Treatment 8 ingredients

4.8 /5
from 17 ratings
Absorbs Well (4) Works Well (3) Light (3)
BrittBrine's avatar

BrittBrine

8 months ago · Sensitive Skin
Review

This has probably been the product that has made the most difference in my skin. It's clearing up breakouts and acne that I've had for the longest...

This has probably been the product that has made the most difference in my skin. It's clearing up breakouts and acne that I've had for the longest time. My skin looks and feels so much better and I've only been using it for about 2-3 months now.

jojoswrld_'s avatar

johari 🪽

6 months ago · Unsure Skin
Review

Works! Doesn’t irritate my skin when used on a dry surface. I hate how my skin looks when it sends all the clogged sebum to the surface of my skin,...

Works! Doesn’t irritate my skin when used on a dry surface. I hate how my skin looks when it sends all the clogged sebum to the surface of my skin, but it clears over time and leaves the skin incredibly firm and smooth. It’s the only not cruelty-free product I use just because it’s benefitted me so greatly and, in my opinion, is indisputably the best prescription-grade retinoid especially for sensitive skin.