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Product Comparison

Here's our complete breakdown comparing the ingredients, attributes, and more of Neutrogena Ageless Intensives Anti-Wrinkle Deep Wrinkle Serum versus Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum .

Last updated on September 14, 2023. Published on July 10, 2021

Overview

What they are

These products are both reef safe serums. They have a total of 8 ingredients in common

Cool Features

They both contain exfoliants, retinoid and Vitamin E

Suited For

They're both likely to be good for fighting acne, dry skin, brightening skin, sensitive skin and dark spots

Free From

They both do not contain any harsh alcohols, common allergens, fragrances, parabens or sulfates

What's Inside

They both contain silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that need an update? Let us know.

Serum American Brand United States
Serum American Brand United States

Serum

Serums are highly concentrated with ingredients to provide skin with benefits. They should be used after cleansing and before moisturizing.

Serum

Serums are highly concentrated with ingredients to provide skin with benefits. They should be used after cleansing and before moisturizing.

Price

Shop

Buy Ageless Intensives Anti-Wrinkle Deep Wrinkle Serum

Starts at $27.82
Shop

Buy Resist Intensive Wrinkle-Repair Retinol Serum

Starts at $45.00

Ingredient Info

Click any item below to learn more and view relevant ingredients.
alcohol-free
silicon-free
fragrance-free
sulfate-free
paraben-free
oil-free
fungal-acne safe
reef-safe
eu-allergen-free
vegan
cruelty-free
alcohol-free
silicon-free
fragrance-free
sulfate-free
paraben-free
oil-free
fungal-acne safe
reef-safe
eu-allergen-free
vegan
cruelty-free

At a glance

Click on any of the items below to learn more

Notable Ingredients

Retinoid
Vitamin E
Exfoliators

Benefits

Hydrating (2)
Redness Reducing
Reduces Irritation (2)
Dark Spots
Acne Fighting
Brightening (3)

Concerns

Drying
Acne Trigger
Rosacea
Eczema

Notable Ingredients

Retinoid
Vitamin C
Vitamin E
Exfoliators

Benefits

Hydrating (3)
Good For Oily Skin
Redness Reducing
Reduces Irritation (2)
Skin Texture (2)
Reduces Large Pores
Anti-Aging (3)
Dark Spots (2)
Scar Healing (2)
Acne Fighting
Brightening (3)

Concerns

Drying
Irritating (2)
Eczema
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Ingredients Side-by-side

Ingredients that are highlighted in purple are present in both products.

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Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1
What it does: Emollient, Skin Conditioning, Solvent
Community Rating: Disliked

Cyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.

D5 is considered lightweight and volatile. Volatile means it evaporates quickly after application. Once evaporated, D5 leaves a thin barrier that helps keep skin hydrated.

D5 is an emollient. Emollients help soften the skin and prevent water loss. Silicones create a silky texture in products. D5 helps other ingredients become more spreadable.

Studies show D5 is safe to use in skincare products. We recommend speaking with a skincare professional if you have concerns.

Learn more about Cyclopentasiloxane

Neutrogena Ageless Intensives Anti-Wrinkle Deep Wrinkle Serum contains this as ingredient number 2.

Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum contains this as ingredient number 1.

2
What it does: Emollient, Skin Conditioning
Community Rating: Loved

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan? This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Learn more about Squalane

Neutrogena Ageless Intensives Anti-Wrinkle Deep Wrinkle Serum contains this as ingredient number 9.

Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum contains this as ingredient number 7.

3
What it does: Masking, Skin Conditioning, Soothing
Community Rating: Loved

Bisabolol is pimarily used to add fragrance to a product. However, it is also famous for helping soothe skin.

Bisabolol comes from German chamomile essential oil. Synthetic Bisabolol has been shown to be less effective.

Bisabolol helps soothe skin. It does this by blocking the inflammatory signals, helping to reduce your body's reaction to irritation.

Bisabolol also interferes with the process of hyperpigmentation. This can help with reducing dark spots and uneven tone.

Bisabolol is an antioxidant. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells. By fighting these free-radicals, Bisabolol may slow down signs of aging.

Studies have shown Bisabolol to have antimicrobial properties and may be a fungicide. These properties help preserve a product's shelf life.

Bisabolol also helps the absorption of other ingredients.

Learn more about Bisabolol

Neutrogena Ageless Intensives Anti-Wrinkle Deep Wrinkle Serum contains this as ingredient number 11.

Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum contains this as ingredient number 8.

4
What it does: Skin Conditioning
Community Rating: Mixed

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Neutrogena Ageless Intensives Anti-Wrinkle Deep Wrinkle Serum contains this as ingredient number 12.

Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum contains this as ingredient number 20.

5
What it does: Masking, Skin Conditioning
Community Rating: Mixed

Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

Within a product, Caprylic Triglyceride can thicken the product and make spreadability easier by dissolving clumping compounds. An added benefit of Caprylic Triglyceride is its antioxidant properties.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid. Caprylic Triglyceride has not been found to be toxic for human use in concentrations under 50%.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride

Neutrogena Ageless Intensives Anti-Wrinkle Deep Wrinkle Serum contains this as ingredient number 14.

Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum contains this as ingredient number 5.

6
What it does: Skin Conditioning
Community Rating: Loved

Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.

Why is retinol famous?

It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.

Retinol is proven to:

This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.

Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).

Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

We recommend speaking with a medical professional about using this ingredient during pregnancy.

Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.

Read about Tretinoin

Learn more about Retinol

Neutrogena Ageless Intensives Anti-Wrinkle Deep Wrinkle Serum contains this as ingredient number 19.

Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum contains this as ingredient number 10.

7
What it does: Antioxidant, Masking, Skin Conditioning
Community Rating: Liked

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol

Neutrogena Ageless Intensives Anti-Wrinkle Deep Wrinkle Serum contains this as ingredient number 20.

Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum contains this as ingredient number 12.

8
What it does: Abrasive, Antioxidant, Emollient, Skin Conditioning
Community Rating: Loved

Avena Sativa Kernel Extract is is derived from colloidal oatmeal. It is formed from grounded oatmeal and a liquid base.

Besides being a healthy breakfast, oats have many benefits in skincare too.

This ingredient helps sooth, hydrate, and protect the skin. The starches in colloidal oatmeal are able to bind water, keeping the skin hydrated.

The cellulose and fiber in colloidal oatmeal help reduce inflammation. This can also help the skin feel softer.

Colloidal Oatmeal is also an antioxidant. Antioxidants help stabilize free-radical molecules. These molecules may damage skin cells.

Avenacins found in colloidal oatmeal have anti-fungal properties. The saponins have a cleaning affect.

Overall, colloidal oatmeal is great at providing the skin with moisture and help sooth irritation. It also protects the skin in various ways.

Learn more about Avena Sativa Kernel Extract

Neutrogena Ageless Intensives Anti-Wrinkle Deep Wrinkle Serum contains this as ingredient number 21.

Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum contains this as ingredient number 15.

Here's what our community thinks of the ingredients in these two products.

48% are loved or liked
14% have mixed ratings
29% are disliked or very disliked
10% have no rating yet
38% are loved or liked
14% have mixed ratings
33% are disliked or very disliked
14% have no rating yet

Usage

Here's some more info on how this product is used by our community.

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Alternatives

Our Dupe Finder has found 10 potential alternatives that have similar ingredients to Neutrogena Ageless Intensives Anti-Wrinkle Deep Wrinkle Serum.

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Our Dupe Finder has found 9 potential alternatives that have similar ingredients to Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum.

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