Explore Routine Login
Versus

Differin Adapalene Gel 0.1% Acne Treatment Versus Neutrogena Rapid Wrinkle Retinol Regenerating Cream - Fragrance

Facial Treatment
General Moisturizer
American Brand United States
American Brand United States

Updated on July 10, 2024

Overview

Cool Features

They both contain retinoid

Suited For

They're both likely to be good for fighting acne and anti aging

Free From

They both do not contain any harsh alcohols, common allergens, oils or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Concerns

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Adapalene Gel 0.1% Acne Treatment
Adapalene
Retinoid IconHelps with Anti-Aging IconHelps fight Acne IconMay cause irritation IconMay worsen Rosacea Icon
RetinoidRetinoid Icon 2 Benefits 2 Concerns

Adapalene is a type of retinoid and common acne treatment.

Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Methylparaben Preservative
0 / 0 Preservative IconParaben IconNon-Reef-Safe IconMay worsen Eczema Icon
PreservativePreservative Icon ParabenParaben Icon 2 Concerns

Methylparaben is a preservative and is a paraben. It is used to prevent the growth of fungus, mold, and other harmful bacteria. Parabens are chemicals used as preservatives in both cosmetics and food.

0 Com. / 0 Irr.
Very Disliked Full details ->
Poloxamer 182 Emulsifying

We don't have a description for Poloxamer 182.

Unknown Full details ->
Propylene Glycol Humectant, Skin Conditioning, Solvent
0 / 0 May worsen Eczema Icon
May worsen EczemaMay worsen Eczema Icon

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

0 Com. / 0 Irr.
Disliked Full details ->
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

Rapid Wrinkle Retinol Regenerating Cream
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Pentaerythrityl Tetraethylhexanoate Emollient

Pentaerythrityl Tetraethylhexanoate is an emollient. Emollients help your skin stay soft and smooth by creating a thin film on top. This film helps trap moisture. It also helps improve the texture of products by adding thickness or helping to create a silky feel.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Dimethicone Emollient, Skin Conditioning, Skin Protecting
1 / 0 Silicon Icon
SiliconSilicon Icon

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

1 Com. / 0 Irr.
Very Disliked Full details ->
Ppg-15 Stearyl Ether Emollient

We don't have a description for Ppg-15 Stearyl Ether.

Very Disliked Full details ->
Stearyl Alcohol Emollient, Emulsifying, Emulsion Stabilising
2 / 2 Fatty Alcohol Icon
Fatty AlcoholFatty Alcohol Icon

Stearyl Alcohol is a type of fatty alcohol from stearic acid. It is a white, waxy compound used to emulsify ingredients.

2 Com. / 2 Irr.
Very Disliked Full details ->
Cetearyl Alcohol Emollient, Emulsifying, Emulsion Stabilising
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon
Fatty AlcoholFatty Alcohol Icon 3 Concerns

Cetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.

2 Com. / 1 Irr.
Very Disliked Full details ->
Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Glyceryl Behenate Emollient, Emulsifying
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Glyceryl Behenate is a fatty acid created from glycerin and behenic acid. It is an emollient and emulsifier.

Disliked Full details ->
Ceteareth-20 Cleansing, Emulsifying
2 / 3 May worsen Oily Skin Icon
May worsen Oily SkinMay worsen Oily Skin Icon

Ceteareth-20 is an emulsifier and cleansing agent. It is derived from cetearyl alcohol, a fatty alcohol.

2 Com. / 3 Irr.
Very Disliked Full details ->
Isohexadecane Emollient, Skin Conditioning, Solvent

Isohexadecane is added to enhance texture, emulsify, and to help cleanse. It is an isoparrafin. It is a component of petrolatum.

Dimethicone Crosspolymer Emulsion Stabilising

Dimethicone Crosspolymer is a silicone created by modifying dimethicone with hydrocarbon side chains. Due to its large size, it does not penetrate skin. It is considered non-occlusive.

Very Disliked Full details ->
Cyclopentasiloxane Emollient, Skin Conditioning, Solvent
Silicon Icon
SiliconSilicon Icon

Cyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.

Disliked Full details ->
Cellulose Absorbent

Cellulose is the main component of plant cell walls. It is used as an emulsifier, absorbent, and texture enhancer.

Sodium Polyacrylate Absorbent, Emollient, Emulsion Stabilising

Sodium Polyacrylate is the sodium salt of polyacrylic acid.

Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Sodium Acryloyldimethyltaurate/Vp Crosspolymer Emulsion Stabilising

We don't have a description for Sodium Acryloyldimethyltaurate/Vp Crosspolymer.

Unknown Full details ->
Polyacrylamide

Polyacrylamide is a synthetic polymer. It is used to stabilize products and bind ingredients. When hydrated, Polyacrylamide forms a soft gel.

Disliked Full details ->
Parfum Masking, Perfuming
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon
FragranceFragrance Icon 2 Concerns

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Very Disliked Full details ->
C13-14 Isoparaffin Emollient, Solvent
May worsen Oily Skin IconNot safe for Fungal Acne Icon
2 Concerns

C13-14 Isoparaffin is created from petroleum-based mineral oils. It is an emollient and helps thicken a product.

Very Disliked Full details ->
Chlorphenesin Antimicrobial, Preservative
Preservative Icon
PreservativePreservative Icon

Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol.

Disliked Full details ->
Polysorbate 20 Emulsifying
0 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

0 Com. / 0 Irr.
Very Disliked Full details ->
Hydrolyzed Myrtus Communis Leaf Extract Skin Protecting

We don't have a description for Hydrolyzed Myrtus Communis Leaf Extract.

Unknown Full details ->
Retinol Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconCan worsen Dry Skin IconMay cause irritation IconMay worsen Eczema Icon
RetinoidRetinoid Icon 8 Benefits 3 Concerns

Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.

BHT Antioxidant, Masking
Antioxidant Icon
AntioxidantAntioxidant Icon

BHT is a synthetic antioxidant. As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.

Very Disliked Full details ->
Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

Laureth-7 Emulsifying

Laureth-7 is created by the ethoxylation of lauryl alcohol using ethylene oxide. Lauryl alcohol is a fatty alcohol with hydrating properties.

Disliked Full details ->
Ascorbic Acid Antioxidant, Buffering, Masking
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon
Vitamin CVitamin C Icon AntioxidantAntioxidant Icon 6 Benefits

Ascorbic Acid is is pure Vitamin C. This form makes up the largest amount of vitamin C found naturally in our skin.

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Disliked

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Buffering
Mixed

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Learn more about Sodium Hydroxide

Ingredient Ratings

Here's what our community thinks of the ingredients in these products.

Adapalene Gel 0.1% Acne Treatment
2
1
4
1
liked
mixed
disliked
not rated
Rapid Wrinkle Retinol Regenerating Cream
8
4
17
2
liked
mixed
disliked
not rated

When to use

1,874 Routines
8% use in am
92% use in pm
75% use every day
When to use See routines that use it ->
6 Routines
17% use in am
83% use in pm
100% use every day

Reviews

Here's what our community thinks

Differin Adapalene Gel 0.1% Acne Treatment 8 ingredients

4.8 /5
from 17 ratings
Absorbs Well (4) Works Well (3) Light (3)
BrittBrine's avatar

BrittBrine

8 months ago · Sensitive Skin
Review

This has probably been the product that has made the most difference in my skin. It's clearing up breakouts and acne that I've had for the longest...

This has probably been the product that has made the most difference in my skin. It's clearing up breakouts and acne that I've had for the longest time. My skin looks and feels so much better and I've only been using it for about 2-3 months now.

jojoswrld_'s avatar

johari 🪽

6 months ago · Unsure Skin
Review

Works! Doesn’t irritate my skin when used on a dry surface. I hate how my skin looks when it sends all the clogged sebum to the surface of my skin,...

Works! Doesn’t irritate my skin when used on a dry surface. I hate how my skin looks when it sends all the clogged sebum to the surface of my skin, but it clears over time and leaves the skin incredibly firm and smooth. It’s the only not cruelty-free product I use just because it’s benefitted me so greatly and, in my opinion, is indisputably the best prescription-grade retinoid especially for sensitive skin.

Neutrogena Rapid Wrinkle Retinol Regenerating Cream 31 ingredients

Rapid Wrinkle Retinol Regenerating Cream hasn't been rated yet.
Rate it now