Dear, Klairs Midnight Blue Youth Activating Drop Versus Coxir Intensive EGF Peptide Serum
Updated on June 10, 2025
Overview
What they are
These products are both reef safe serums. They have a total of 7 ingredients in common
Cool Features
They both contain peptides
Suited For
They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores and scar healing
Free From
They both do not contain any common allergens, parabens, silicones or sulfates
What's Inside
They both contain fragrances
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Dear, Klairs Midnight Blue Youth Activating Drop 15 ingredients
Coxir Intensive EGF Peptide Serum 35 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
Dear, Klairs Midnight Blue Youth Activating Drop 15 ingredients
Coxir Intensive EGF Peptide Serum 35 ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningButylene Glycol
Humectant
Sh-Oligopeptide-1
Skin Conditioning
Sh-Polypeptide-1
Skin Conditioning
Vaccinium Angustifolium Fruit Extract
Skin Protecting
Lecithin
Emollient
Sorbitan Sesquioleate
Emulsifying
1,2-Hexanediol
Skin Conditioning
Caprylyl Glycol
EmollientPEG-60 Hydrogenated Castor Oil
Emulsifying
Glycerin
Humectant
Chlorphenesin
Antimicrobial
Guaiazulene
Antimicrobial
Ethylhexylglycerin
Skin ConditioningAdenosine
Skin Conditioning
Water
Skin ConditioningButylene Glycol
Humectant
Glycerin
Humectant
Alcohol
Antimicrobial
Propylene Glycol
Humectant
Niacinamide
Smoothing
1,2-Hexanediol
Skin Conditioning
Betaine
Humectant
Glyceryl Acrylate/Acrylic Acid Copolymer
HumectantPvm/Ma Copolymer
Emulsion StabilisingPEG/PPG-18/4 Copolymer
SolventAllantoin
Skin Conditioning
Triethanolamine
BufferingAdenosine
Skin Conditioning
Lonicera Japonica Flower Extract
Skin ConditioningSolanum Lycopersicum Fruit Extract
Antioxidant
Lilium Tigrinum Extract
Skin ConditioningNelumbo Nucifera Flower Extract
Skin ConditioningChrysanthemum Indicum Flower Extract
Skin ConditioningHydrogenated Lecithin
Emulsifying
Sh-Oligopeptide-1
Skin Conditioning
Copper Tripeptide-1
Skin Conditioning
Hydrolyzed Collagen
Emollient
Acanthopanax Senticosus Root Extract
Skin ConditioningPunica Granatum Extract
AstringentCarthamus Tinctorius Flower Extract
Skin ConditioningCarbomer
Emulsion StabilisingLeontopodium Alpinum Extract
Skin ConditioningThymus Vulgaris Extract
Perfuming
Malva Sylvestris Flower Extract
Skin ConditioningBambusa Vulgaris Callus Culture Extract
Skin ConditioningSnail Secretion Filtrate
Skin Conditioning
Phenoxyethanol
Preservative
Ethylhexylglycerin
Skin ConditioningParfum
Masking
Water, Butylene Glycol, Glycerin, Alcohol, Propylene Glycol, Niacinamide, 1,2-Hexanediol, Betaine, Glyceryl Acrylate/Acrylic Acid Copolymer, Pvm/Ma Copolymer, PEG/PPG-18/4 Copolymer, Allantoin, Triethanolamine, Adenosine, Lonicera Japonica Flower Extract, Solanum Lycopersicum Fruit Extract, Lilium Tigrinum Extract, Nelumbo Nucifera Flower Extract, Chrysanthemum Indicum Flower Extract, Hydrogenated Lecithin, Sh-Oligopeptide-1, Copper Tripeptide-1, Hydrolyzed Collagen, Acanthopanax Senticosus Root Extract, Punica Granatum Extract, Carthamus Tinctorius Flower Extract, Carbomer, Leontopodium Alpinum Extract, Thymus Vulgaris Extract, Malva Sylvestris Flower Extract, Bambusa Vulgaris Callus Culture Extract, Snail Secretion Filtrate, Phenoxyethanol, Ethylhexylglycerin, Parfum
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.Â
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesÂ
Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.
Studies have found adenosine may also help with wound healing.
In skincare products, Adenosine is usually derived from yeast.
Learn more about AdenosineButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about Glycerinsh-Oligopeptide-1 is a peptide found naturally in our bodies. Peptides are the building blocks for collagen and elastin in our skin.
In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.
Studies find EGF help with:
In South Korea and China, EGF is considered a controversial ingredient. The South Korean Ministry of Food and Drug Safety has cracked down on companies with products including EGF due to false advertisement claims.
According to Dr. Zoe Draelos, growth factors have some drawbacks:
There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.
Learn more about Sh-Oligopeptide-1Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterIngredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Dear, Klairs Midnight Blue Youth Activating Drop 15 ingredients
Coxir Intensive EGF Peptide Serum 35 ingredients
Reviews
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