ChapStick Medicated Chapstick

Pro tip: Use occlusives, such as this ingredient, on damp skin for the best results.

The quality or origin of petrolatum is only known when disclosed by the brand. Most cosmetic petrolatum has gone through several purification stages.

Another benefit of occlusives is it protects your skin against infection or allergies.

Petrolatum is fungal acne safe. It is a hydrocarbon with no fatty acid structure, so Malassezia cannot metabolize it. In-vitro studies support negligible growth stimulation as well.

It's also worth noting that petrolatum has a comedogenic rating of 0. In updated rabbit ear testing (and in human testing), petrolatum was found to be not comedogenic. This means it didn’t promote comedone formation in standard models.

It works by denaturing proteins, which is what gives it both its antimicrobial activity and its potential to cause chemical burns, redness, peeling, or stinging. Phenol also has a mild local anesthetic effect, so irritation may not be felt right away even when damage is occurring. The lips and other thin-skinned areas are especially susceptible.

The use of phenol in cosmetics is prohibited in the European Union and Canada. In the United States, it remains permitted primarily in OTC drug products such as oral analgesics and medicated lip balms.

Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.

The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.

It has a very saturated profile (stearic acid ~34 to 36%, oleic acid ~30 to 40%, and palmitic acid ~24 to 29%) that makes it a strong occlusive: it sits on top and slows water escaping from skin.

Concentration data shows that it can show up anywhere from a few percent in lotions up to 100% in balms, and the FDA lists cocoa butter as an OTC skin protectant active at 50-100%.

The CIR has reviewed it and concluded it to be safe as used in cosmetics.

This is one of the ingredients with a comedogenic score of 4/5 from the rabbit ear test. Just know that a later human study did find that finished products containing high-comedogenic ingredients like cocoa butter did not increase microcomedone formation.

The fair call here is that this ingredient is most likely fine on body or low-percentage formulas, but can potentially be riskier as a heavy leave-on facial product if you break out easily.

Cocoa butter may not be fungal acne safe; it is a triglyceride of C16-18 fatty acids that the Malassezia yeast can metabolize.

Allergies to cocoa butter are rare and uncommon, but a few cases have been documented (mostly in cases where the person ate chocolate). So if you have a tree nut allergy, be sure to patch test or avoid.

For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.

The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

A 2019 review found a maximum reported use level of 14.5% in a lipstick. Concentrations range from 2.7-14.5% in lipsticks, ~6% in eyeliners, ~1.5% in body/hand products, and 0.05% in moisturizers.

This ingredient does have a comedogenic rating of 3, but this doesn't mean a formula with this ingredient will clog pores. Human testing has proved that any finished product with this ingredient won't automatically make you break out; it really comes down to concentration, formula, and your skin.

The Malassezia yeast can metabolize fatty acids in the C11-24 range, and Isopropyl Lanolate is an ester of lanolin fatty acids spanning C12-34. This puts it right inside the range, making it potentially unsafe for fungal acne.

Allergy data shows that patch tests on formulations containing 6% and 14% produced no contact allergy but pure 100% Isopropyl Lanolate produced sensitization reactions in 2 of 52 subjects. The broader concern is that lanolin as a family is a genuine contact allergen with reported prevalence across studies ranging from 1.2-6.9% of patients reacting to it. Most of these reports came from people who developed allergies after repeated or prolonged use on damage skin.

This ingredient is generally considered non-toxic, non-irritating, and has low absorption potential.

This ingredient does have a comedogenic rating of 3-5, but this doesn't mean a formula with this ingredient will clog pores.

Dermatologist Dr. Zoe Draelos has also confirmed in a peer-reviewed paper that products containing comedogenic ingredients are not necessarily comedogenic themselves.

A small subset of people (~2%) may experience contact sensitivity so patch testing is a reasonable idea if you have reactive skin.

Since this ingredient is an ester of myristic acid (a C14 fatty acid), it falls within the carbon chain range that is known to feed Malassezia. This ingredient may not be fungal acne safe.

On the other hand, lanolin is able to reduce transepidermal water loss (TEWL) by about 20-30%. It can also incorporate into the lipid matrix to surround skin cells and reinforce the skin barrier.

This is why you'll see lanolin as an ingredient for heavy-duty moisturizers.

You might have seen an "allergy concern" that gives lanolin a bad reputation. The rate of lanolin contact allergy in the general population is estimated to be under 0.5%, and most of these are seen in people with compromised-skin dealing with eczema, atopic dermatitis, or leg ulcers.

Healthy, intact skin tolerates lanolin well. Even people who have previously reacted to it test negative on patch tests when the test is done on normal skin.

Because lanolin comes from an animal, it is not considered vegan. Sheep secrete lanolin through sebaceous glands to help protect their skin from the environment.

Lanolin has a reputation as pore clogging but that comes almost entirely from rabbit ear testing done decades ago (and that model has aged badly).

This ingredient does have a comedogenic rating of 0-1; the tests state this score means the ingredient has low or non-existent chance of clogging your pores.

Keep in mind that the authors of the rabbit ear test proposed that a material needs to score consistently above 3 in the rabbit assay before it means anything for real skin.

A separate review found the model has serious performance problems and no correlation with human experience. Concentration matters a lot too: in one study, Acetylated Lanolin Alcohol scored 4 to 5 at full strength but dropped to a 1 when diluted to 2.5%, and finished products containing "comedogenic" ingredients didn't raise microcomedone counts in people.

Lanolin contains esters exactly in the range that the Malassezia yeast can synthesize, making this ingredient not fungal acne safe.

As an occlusive, it forms a protective layer on the skin that locks in moisture and prevents transepidermal water loss (TEWL). This makes it especially great for compromised skin barriers.

The "it clogs your pores" myth has been around for decades; a study found that industrial-grade mineral oil may be comedogenic but cosmetic-grade mineral oil is not (these two are very, very different).

A 2017 review concluded that cosmetic use of mineral oils and waxes does not present a risk to consumers due to absorption.

Mineral oil got a bad rap from the old rabbit ear studies. When tested on actual human skin, cosmetic-grade mineral oil showed no comedogenic activity. The rating of 0 is a correction of outdated science.

Mineral oil is an inert substance with no fatty acids so there's nothing to feed Malassezia. This ingredient is fungal acne safe.

This is also one of the most heavily studied preservatives out there and major regulatory bodies have repeatedly given it the green light.

In 2023, the EU's Scientific Committee on Consumer Safety (SCCS) confirmed that this ingredient is safe up to 0.4% on its own, of up to 0.8% when mixed with other paraben esters.

Here's the science behind the noise behind parabens/hormones as well:

Methylparaben shows very weak estrogen-like activity in vitro tests (more than 1,000x weaker than your body's own estradiol). In vivo (live-organism) studies don't support a meaningful endocrine-disrupting effect either.

You get a stronger estrogenic effect from eating tofu, actually.

It's also a low sensitizer and allergic reactions are uncommon; they usually happen on damage or broken skin.

There is a caveat: France has proposed to formally re-examine its endocrine classification in 2025 so the regulatory conversation isn't fully closed as of yet.

But as it stands today, this ingredient is considered safe at permitted levels.

You'll likely see this in many BHA products because this is the go-to solvent for salicylic acid.

This ingredient is typically used at levels between 2-20%.

Regarding fungal acne:
In 2019, this ingredient was tested against multiple Malassezia species (the yeast that causes fungal acne) and showed no growth.

Its job in a formula is boring, but useful:

Typical concentrations range from 0.1-50% and it's usually low single digits in leave-on skincare.

One thing that sets it apart from other fatty alcohols is that it's used deliberately as a penetration enhancer in topical drug delivery. This is because it "loosens" the packing of your skin's surface lipids a bit so other ingredients can get through more easily.

A study on human skin found both Oleic Acid and Oleyl Alcohol at 0.75% increased how much topical anti-inflammatory drug got through with the effect leveling off after about 12 hours.

Allergic reactions are uncommon but documented; there's a published case of a patient with atopic dermatitis who developed severe allergic contact dermatitis from a prescription cream. A patch testing traced it specifically to the Oleyl Alcohol in the formula rather than the active drug.

The Cosmetic Ingredient Review Expert Panel concluded Oleyl Alcohol is safe as used in cosmetics. Acute toxicity testing showed very low toxicity, animal tests showed minimal to mild skin irritation, human patch testing found low irritation and sensitization potential, and no phototoxicity or photosensitization has been reported.

It's reasonable to patch test if you have eczema, a known fatty alcohol allergy, or you've reacted to Stearyl or Cetyl Alcohol before.

Oleyl Alcohol scored a 4 out of 5 for comedogenicity in the 1989 rabbit ear study. Just know the rabbit ear test has real limits:

It's worth watching if you're acne-prone and how you will react to it really comes down to concentration, formula, and your skin.

The culprit behind fungal acne, the Malassezia yeast, feeds on fatty acids with carbon chain lengths between C11-C24. Oleic Acid, at C18, falls right into that sweet spot.

In vitro studies have shown that Oleic Acid is one of the fatty acids that induce rapid Malassezia growth in lab settings. Since this ingredient is created from Oleic Acid, it may not be fungal acne safe.

You'll likely see it paired with methylparaben to cover the full range (including gram-negative bacteria).

This ingredient is effective at low concentrations (~0.2-0.5%) and stable across a wide pH range (4.5-7.5 pH). It's effectiveness drops off above pH 8 and it can lose potency when combined with non-ionic surfactants like polysorbate 80 due to micellization.

The regulatory bodies have concluded this ingredient to be safe as used in cosmetics. The EU has capped it at 0.14% and combined parabens are not to exceed 0.8%.

While parabens do cross the stratum corneum, only about 1% remains for absorption into the body. This is because most of it is metabolized within living skin.