Bruna Tavares BT Lacebrow

It is considered non-comedogenic and vegan-friendly.

This ingredient has a well-established safety record by the CIR Expert Panel for Cosmetic Ingredient Safety.

Synthetic Waxes are straight/branched-chain hydrocarbons with no ester bond or fatty acids. That means there is nothing for the Malassezia yeast to feed on.

Isododecane's role as a solvent makes it a great texture enhancer. It spreads smoothly on skin and does not leave a sticky feeling behind. Isododecane also helps prevent color transfer in makeup products.

Isododecane is not absorbed into skin.

The chemical name for this ingredient is 2,2,4,6,6-PENTAMETHYLHEPTANE.

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Besides holding formulas together, it also leaves a silky and lightweight feel on skin without the greasiness. A manufacturer also claims it can help with the controlled release of active ingredients.

The CIR Expert Panel found this ingredient to not be sensitizing in concentrations up to 15% in human maximazation testing and dimethicone-based compounds were not comedogenic.

It has a high molecular weight well above 1,000 g/mol which means it limits meaningful skin penetration.

A 2019 study specifically tested this ingredient and found no observable Malassezia growth in its presence.

In skincare, it is an emollient that dries down to a solid film with water-binding properties. This helps keep skin hydrated and helps reduce transepidermal water loss (TEWL).

A 2026 dermatology review pulls together its broader uses:

Human clinical testing found this ingredient to be non-irritating and non-sensitizing.

Because castor oil contains fatty acids in the C11-24 range, this ingredient may not be fungal acne safe.

At this time, the literature does not support castor oil in regrowing hair. A 2022 systematic review found no strong evidence that it supports hair growth and only weak evidence that it improves hair shine.

Castor oil itself carries "perfuming" and "masking" function tags according to the official CosIng database. This is because of its mild odor and odor-dampening properties.

The highest reported concentration is about 24% in eye makeup but most suppliers recommend a level below 10%.

It has a clean track record for safety and found to be non-irritating.

Because it is an ester of a C18 fatty acid, Malassezia can potentially metabolize it (it sits in the C11-24 range that Malassezia likes). Therefore, this ingredient may not be fungal acne safe.

Because of its structure, it also acts as a mild skin conditioning emollient that helps soften skin while preventing moisture loss.

Safety studies show it to be safe and non-irritation in clinical tests. It's typically used in concentrations up to 5%.

Since its an ester of a C18 fatty acid, it falls into the C11-24 range that Malassezia can potentially feed on. This makes it not fungal-acne safe.

It's a well-vetted ingredient for safety and does not penetrate into skin due to its large molecule size.

Because it's a long-chain fatty acid ester, this ingredient may not be fungal acne or Malassezia safe.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

The unique structure of silica enhances the spreadability and adds smoothness, making it a great texture enhancer.

It is also used as an active carrier, emulsifier, and mattifier due to its ability to absorb excess oil.

In some products, tiny microneedles called spicules are made from silica or hydrolyzed sponge. When you rub them in, they lightly polish away dead skin layers and enhance the penetration of active ingredients.

While MAP is gentler on the skin than ascorbic acid, it is thought to be less easily absorbed into the skin.

In a well-known absorption study, pure vitamin C increased skin vitamin C levels when formulated correctly, but derivatives like MAP did not in that experiment. This suggests MAP may not always convert into active vitamin C in the skin.

Due to MAP's stability up to a pH level of 7, it is more stable to air and sunlight exposure than ascorbic acid. The best pH range for MAP is between 5 and 6.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

In skincare, this process helps regulate sebum production. One study found topical L-carnitine can help reduce excess oil and improve skin oil balance. This makes it a great addition for oily or acne-prone skin.

Besides oil control, carnitine supports healthy skin metabolism by boosting lipid breakdown. Research has shown it can improve skin’s resilience against aging and external stressors like UV exposure.

There are no downsides to using this ingredient and it is a great multifunctional ingredient for both sebum regulation and anti-aging care.

According to manufacturers, this ingredient is an emollient and humectant. This means it helps hydrate the skin.

In medicine, this ingredient is used to help relieve heartburn and help heal ulcers.

There is currently no credible scientific evidence linking aluminum hydroxide in cosmetics to increased cancer risk.

Major health organizations allow the use of aluminum hydroxide in personal care products and have not flagged it as a carcinogenic risk at typical usage levels.

Ci 77891 is commonly found in sunscreens due to its ability to block UV rays.

Synthetically created CI 77492 is considered safer than those naturally found. This is because the synthetically created version may contain less impurities. Iron oxides are generally non-toxic and non-allergenic.

Synthetically created Ci 77491 is considered safer than those naturally found. This is because the synthetically created version may contain less impurities. Iron oxides are generally non-toxic and non-allergenic.

In the US, this ingredient can only be used if it meets strict FDA specifications. Certain versions even require batch-by-batch certification after extensive safety evaluation.

In the European Union, this ingredient is permitted as a colorant and classified as a "nanomaterial" based on its particle size (meaning it requires deeper assessment).

The EU Scientific Committee on Consumer Safety (SCCS) has reviewed nano-sized carbon black specifically and concluded that it does not pose a risk to human health when used in cosmetic products applied to healthy, intact skin and formulated to avoid inhalation.

Studies support this regulatory stance. Laboratory studies on nano-carbon black show potential for cytotoxicity and inflammatory effects in immune cells; it is important to highlight these findings are based on in vitro (not done on a living organism) testing or inhalation scenarios rather than normal topical cosmetic use.

Occupational studies involving industrial workers exposed to airborne carbon black have not shown a clear link between cumulative exposure and cancer risk. These findings are not directly applicable to cosmetics; cosmetic formulations bind pigments within creams, gels, and liquids that are not inhaled.

Overall, evidence shows that this ingredient is safe under regulatory guidelines and purity standards, especially when formulated to avoid airborne exposure.

Even with regulatory approval and a long history of use, some consumers might prefer to avoid ingredients that are petroleum-derived or that fall under the “nanomaterial” category.

Choosing whether to use CI 77266 isn’t necessarily about safety alone; it can also be about personal philosophy, comfort level with synthetic versus natural ingredients, and how much weight you place on ongoing research and regulatory oversight.

Makeup is highly individual, and personal preference plays an important role in deciding what feels right for you.