BioNike Defence Gentle Face Scrub
A exfoliator with 29 ingredients, including vitamin E and urea.
This smoothing exfoliator is formulated around Perlite and Urea to refine skin texture and balance excess oil.
We independently verify ingredients, backed by peer-reviewed research. Suggest an update.
What's inside
Ingredients List
Water
Skin ConditioningMethylpropanediol
Solvent1,5-Pentanediol
SolventPerlite
Absorbent1,2-Hexanediol
Skin ConditioningAmmonium Acryloyldimethyltaurate/Vp Copolymer
Lactose
HumectantCellulose
AbsorbentTocopheryl Acetate
AntioxidantBetaine
HumectantGlycerin
HumectantUrea
BufferingCalcium Pantothenate
Magnesium Lactate
BufferingPapain
Skin ConditioningMaltodextrin
AbsorbentCaprylyl Glycol
EmollientPotassium Lactate
BufferingAlanine
MaskingProline
Skin ConditioningSerine
MaskingHydroxypropyl Methylcellulose
Emulsion StabilisingEthylhexylglycerin
Skin ConditioningXanthan Gum
EmulsifyingMagnesium Chloride
Sodium Citrate
BufferingCI 73360
Cosmetic ColorantCI 77891
Cosmetic ColorantTrisodium Ethylenediamine Disuccinate
Water, Methylpropanediol, 1,5-Pentanediol, Perlite, 1,2-Hexanediol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Lactose, Cellulose, Tocopheryl Acetate, Betaine, Glycerin, Urea, Calcium Pantothenate, Magnesium Lactate, Papain, Maltodextrin, Caprylyl Glycol, Potassium Lactate, Alanine, Proline, Serine, Hydroxypropyl Methylcellulose, Ethylhexylglycerin, Xanthan Gum, Magnesium Chloride, Sodium Citrate, CI 73360, CI 77891, Trisodium Ethylenediamine Disuccinate
Key Ingredients
Benefits
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterMethylpropanediol is a synthetic solvent and humectant.
As a solvent, it helps dissolve other ingredients, helping to evenly distribute ingredients throughout the product. This ingredient has also been shown to have antimicrobial properties which makes it a preservative booster.
Methylpropanediol is able to add a bit of moisture to the skin. It also helps other ingredients be better absorbed into the skin, such as salicylic acid.
Learn more about MethylpropanediolWe don't have a description for 1,5-Pentanediol yet.
Perlite can be good for oily skin. It can help to reduce large pores.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Ammonium Acryloyldimethyltaurate/Vp Copolymer is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.
Think of it as a supportive ingredient that helps your gel-creams feel silky, "cloud cream-like", and spread evenly without being greasy.
The Cosmetic Ingredient Review (CIR) Expert Panel evaluated it (along with 22 other acryloyldimethyltaurate polymers) and concluded it's:
Due to its large molecular size, it sits on the surface of skin rather than penetrating it.
Learn more about Ammonium Acryloyldimethyltaurate/Vp CopolymerLactose is a naturally derived milk sugar with humectant and skin conditioning properties. It helps draw and hold moisture in the outermost layer of skin.
The Cosmetic Ingredient Review (CIR) concludes lactose is generally considered low risk for irritation in topical products.
By the way, lactose is not an exfoliating acid like lactic acid or lactobionic acid. And since it's typically animal-derived, it's not usually vegan.
Learn more about LactoseCellulose is the main component of plant cell walls. It is used as an emulsifier, absorbent, and texture enhancer.
This ingredient has many functions:
Fun fact: Cellulose is the most abundant form of organic polymer on Earth.
Learn more about CelluloseTocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Learn more about Tocopheryl AcetateBetaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. It’s known for being gentle and for helping the skin maintain balanced hydration.
Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.
Some studies suggest betaine may support making skin tone more even.
Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.
Betaine is also known as trimethylglycine.
Learn more about BetaineGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinUrea is also called carbamide and is the diamide of carbonic acid. In cosmetics, urea is used to hydrate the skin. It also provides exfoliation in higher concentrations.
As a humectant, urea helps draw moisture from the air and from deep within the skin. This helps hydrate your skin. Studies show urea is an effective moisturizer for dry skin conditions. 40% urea is typical in medications for treating eczema and other skin conditions.
Urea has the strongest exfoliation effect in concentrations higher than 10%. It is a keratolytic agent, meaning it breaks down the keratin protein in the top layer of skin. This helps remove dead skin cells and flaking skin.
In medicine, urea has been shown to help increase the potency of other ingredients, such as fungal treatments.
Humans and animals use urea to metabolize nitrogen-containing compounds. Urea is highly soluble in water. Once dissolved, it is neither acidic nor alkaline.
Urea is actually one of the more well-studied and well-supported ingredients out there if you have eczema.
Clinical trials have shown that urea creams in the 5 - 10% range can:
Higher concentrations (20 -30%) can also help with thickened, scaly patches but is also more likely to sting on active flares.
Skip urea if you have rosacea. The AAD (American Academy of Dermatology) lists it alongside alcohol, menthol, and fragrance as a potential irritant for rosacea-prone skin. Urea's keratolytic and penetration-enhancing properties can trigger stinging, burning, and redness.
As always, your skin is unique, so definitely check in with your dermatologist.
Learn more about UreaCalcium Pantothenate is calcium salt from Vitamin B5. It can be naturally found in plants and animals.
Calcium Pantothenate is a potent antioxidant. Antioxidants help fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material. Antioxidants help stabilize free-radicals by donating extra electrons. This may help reduce the signs of aging.
Our bodies use Calcium Pantothenate for various metabolic functinos. These functions include metabolizing carbohydrates, proteins, and fatty acids.
Learn more about Calcium PantothenateWe don't have a description for Magnesium Lactate yet.
Papain is a proteolytic enzyme extracted from unripe papaya fruit. It is a gentle exfoliator that helps remove the dead skin cells from your outermost layer of skin.
Basically, papain works by dissolving the "glue" holding dead skin cells to your skin's surface. This also promotes cell turnover and smooths texture.
Unlike other exfoliants, papain can work without causing significant irritation.
Beyond exfoliation, its proteolytic action also helps soothe irritated skin and supports the healing of minor wounds.
A 2024 in vivo/in vitro study confirmed its potential to suppress skin inflammation and improve transepidermal water loss (TEWL) in atopic dermatitis models.
Just one thing worth noting: there are reports of allergic responses in individuals with a papaya or latex sensitivity. Be sure to patch test if you're in this camp.
Learn more about PapainMaltodextrin is a plant-derived carbohydrate made by breaking down starch (usually from corn, potato, or rice). In cosmetic formulas, it's a multitasking absorbent, emulsion stabilizer, and skin conditioner.
This ingredient is mostly used to stabilize emulsions and improve the powdery, non-greasy feel of products (like dry shampoos).
Safety-wise, this ingredient is pretty solid; it's even recognized as a food additive. Both animal and clinical studies found no adverse effects at the levels used in cosmetics.
Industry data shows this ingredient is used up to 45.7% in spray products and up to 33% in powder products.
Learn more about MaltodextrinCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolPotassium lactate is the potassium salt of lactic acid. It has humectant, skin conditioning, and buffering properties.
This ingredient is an effective humectant because of its ability to hold onto water (like hyaluronic acid). This helps the skin maintain hydration.
Besides hydration, this ingredient is also a buffer and helps stabilize the pH of formulations.
Learn more about Potassium LactateAlanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.
Proline is a non-essential amino acid, meaning your body can make it on its own. In skincare, it is a skin conditioning ingredient that keeps skin soft and hydrated.
It makes up about 23% of the collagen molecule (collagen is the protein responsible for keeping your skin firm) and is involved in your skin's natural hyaluronic acid production. When applied topically, proline can penetrate the skin fairly well due to its small molecular size.
Reviews of this ingredient have found it to be neither a dermal irritant nor a sensitizer.
Fun fact: Proline can be found in protein-rich foods like meat, fish, eggs, and dairy.
Learn more about ProlineSerine is a non-essential amino acid (your body makes it on its own!). It is a major player in your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Serine is one of your NMF's most abundant components that works as a skin-identical humectant. Its hydroxyl group grabs onto water molecules to boost hydration without any heaviness or occlusion.
Research on a hydrogel with serine confirmed this serine got delivered to your stratum corneum and demonstrated enhanced skin moisturization.
Interestingly serine also helps your skin produce filaggrin, a protein that keeps your skin barrier strong and used to create collagen.
Learn more about SerineThis ingredient is a semi-synthetic polymer created from cellulose. In case you need a refresher, cellulose is the main component of plant cell walls.
Hydroxypropyl Methylcellulose has many uses:
- emulsifier
- create a gel-like texture
- boost foam
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumMagnesium chloride is a mineral salt made from magnesium and chloride. It is mainly used to control product stability and texture in cosmetics.
This ingredient can also play a role in soothing the skin and supporting normal skin function.
Magnesium chloride is water-soluble, generally well tolerated, and does not act as a strong “active” ingredient on its own.
Learn more about Magnesium ChlorideSodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.
Its main functions are to maintain the pH of a product and neutralize metal ions.
The acidity of our skin is maintained by our glands and skin biome; normal pH level of skin is slightly acidic (~4.75-5.5).
Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.
Learn more about Sodium CitrateCi 73360 is a synthetic red-pink dye.
It is soluble in water and remains chemically stable across a range of pH levels typically used in cosmetics. This helps manufacturers maintain uniform color throughout a product’s shelf life.
Because this ingredient is a regulated cosmetic colorant, its purity, manufacturing standards, and allowed uses are defined by cosmetic regulations in major markets.
Learn more about CI 73360Ci 77891 is a white pigment from Titanium dioxide. It is naturally found in minerals such as rutile and ilmenite.
It's main function is to add a white color to cosmetics. It can also be mixed with other colors to create different shades.
Ci 77891 is commonly found in sunscreens due to its ability to block UV rays.
Learn more about CI 77891Trisodium Ethylenediamine Disuccinate is used to help stabilize a product.
It is a chelating agent, meaning it helps prevent metal ions from binding to other ingredients. This prevents unwanted reactions in products. Metal ions can come into a product via the water ingredient. They are found in trace amounts and are not known to be harmful.
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Where it's from
BioNike is a Italian brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Published April 7, 2026 • Added by Rieza