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Ecological Formulas Melazepam Versus Curology Custom Formula (Tretinoin 0.01% Azelaic acid 2% Niacinamide 4%)

Facial Treatment
Prescription
American Brand United States
American Brand United States

Updated on July 26, 2024

Overview

What they are

These products are both reef safe . They have a total of 6 ingredients in common

Suited For

They're both likely to be good for fighting acne, reducing pores, scar healing and dark spots

Free From

They both do not contain any parabens, silicones or sulfates

What's Inside

They both contain fragrances

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Benefits

Concerns

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Melazepam
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Azelaic Acid Buffering, Masking
Helps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne Icon
5 Benefits

Azelaic acid is a naturally occurring acid derived from grains. This ingredient is effective in treating acne, rosacea, and other skin conditions.

Cetearyl Alcohol Emollient, Emulsifying, Emulsion Stabilising
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon
Fatty AlcoholFatty Alcohol Icon 3 Concerns

Cetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.

2 Com. / 1 Irr.
Very Disliked Full details ->
Ceteareth-20 Cleansing, Emulsifying
2 / 3 May worsen Oily Skin Icon
May worsen Oily SkinMay worsen Oily Skin Icon

Ceteareth-20 is an emulsifier and cleansing agent. It is derived from cetearyl alcohol, a fatty alcohol.

2 Com. / 3 Irr.
Very Disliked Full details ->
Paraffinum Liquidum Emollient, Skin Protecting, Solvent
0-2 / 0 Oil IconMay worsen Oily Skin IconNot safe for Fungal Acne Icon
OilOil Icon 2 Concerns

Paraffinum Liquidum is also known as liquid paraffin. It is a type of highly refined mineral oil.

0-2 Com. / 0 Irr.
Very Disliked Full details ->
Propylene Glycol Humectant, Skin Conditioning, Solvent
0 / 0 May worsen Eczema Icon
May worsen EczemaMay worsen Eczema Icon

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

0 Com. / 0 Irr.
Disliked Full details ->
Petrolatum Emollient
Oil IconMay worsen Oily Skin IconNot safe for Fungal Acne Icon
OilOil Icon 2 Concerns

Petrolatum is more commonly known as petroleum jelly. It is created by mixing waxes and mineral oils.

Disliked Full details ->
C12-15 Alkyl Benzoate Antimicrobial, Emollient, Skin Conditioning

C12-15 Alkyl Benzoate is made up of Benzoic Acid and long chain alcohols. It has a low molecular weight.

Disliked Full details ->
Carthamus Tinctorius Seed Oil Masking, Skin Conditioning
0-2 / 0 Oil IconNot safe for Fungal Acne Icon
OilOil Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Carthamus tinctorius seed oil comes from safflower, one of humanity's oldest crops.

0-2 Com. / 0 Irr.
Disliked Full details ->
Polyacrylamide

Polyacrylamide is a synthetic polymer. It is used to stabilize products and bind ingredients. When hydrated, Polyacrylamide forms a soft gel.

Disliked Full details ->
C13-14 Isoparaffin Emollient, Solvent
May worsen Oily Skin IconNot safe for Fungal Acne Icon
2 Concerns

C13-14 Isoparaffin is created from petroleum-based mineral oils. It is an emollient and helps thicken a product.

Very Disliked Full details ->
Laureth-7 Emulsifying

Laureth-7 is created by the ethoxylation of lauryl alcohol using ethylene oxide. Lauryl alcohol is a fatty alcohol with hydrating properties.

Disliked Full details ->
Glyceryl Stearate Emollient, Emulsifying
1 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Glyceryl Stearate is a mix of glycerin and stearic acid.

1 Com. / 0 Irr.
Disliked Full details ->
Peg-100 Stearate
0 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Peg-100 Stearate is an emollient and emulsifier. PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.

0 Com. / 0 Irr.
Very Disliked Full details ->
Isopropyl Alcohol Solvent
0 / 0 Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon
AlcoholAlcohol Icon 5 Concerns

Isopropyl Alcohol is more commonly known as rubbing alcohol. It is most commonly used as a solvent, meaning it helps other ingredients dissolve.

0 Com. / 0 Irr.
Very Disliked Full details ->
Carnitine Cleansing, Skin Conditioning

We don't have a description for Carnitine.

Unknown Full details ->
Benzyl Alcohol Perfuming, Preservative, Solvent
Alcohol IconFragrance IconPreservative IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon
AlcoholAlcohol Icon FragranceFragrance Icon PreservativePreservative Icon 6 Concerns

Benzyl Alcohol is most commonly used as a preservative. It also has a subtle, sweet smell. Small amounts of Benzyl Alcohol is not irritating and safe to use in skincare products. Most Benzyl Alcohol is derived from fruits such as apricots.

Very Disliked Full details ->
Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Potassium Sorbate Preservative
Preservative Icon
PreservativePreservative Icon

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

Disliked Full details ->
Custom Formula (Tretinoin 0.01% Azelaic acid 2% Niacinamide 4%)
Tretinoin
Retinoid IconHelps with Anti-Aging IconHelps fight Acne IconHelps brighten skin IconMay cause irritation IconMay worsen Rosacea Icon
RetinoidRetinoid Icon 3 Benefits 2 Concerns

Tretinoin is the best retinoid due to its proven skin benefits. It only available with a prescription in many countries.

Azelaic Acid Buffering, Masking
Helps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne Icon
5 Benefits

Azelaic acid is a naturally occurring acid derived from grains. This ingredient is effective in treating acne, rosacea, and other skin conditions.

Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Aloe Barbadensis Leaf Juice Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation Icon
2 Benefits

Aloe Barbadensis Leaf Juice comes from leaves of the aloe plant. Aloe Barbadensis Leaf Juice is best known for helping to soothe sunburns. It is also anti-inflammatory, moisturizing, antiseptic, and can help heal wounds.

C13-14 Isoparaffin Emollient, Solvent
May worsen Oily Skin IconNot safe for Fungal Acne Icon
2 Concerns

C13-14 Isoparaffin is created from petroleum-based mineral oils. It is an emollient and helps thicken a product.

Very Disliked Full details ->
Caprylic/Capric Triglyceride Masking, Skin Conditioning

Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Laureth-7 Emulsifying

Laureth-7 is created by the ethoxylation of lauryl alcohol using ethylene oxide. Lauryl alcohol is a fatty alcohol with hydrating properties.

Disliked Full details ->
Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
Polyacrylamide

Polyacrylamide is a synthetic polymer. It is used to stabilize products and bind ingredients. When hydrated, Polyacrylamide forms a soft gel.

Disliked Full details ->
Tocopheryl Acetate Antioxidant, Skin Conditioning
0 / 0 Vitamin E IconAntioxidant IconHelps brighten skin Icon
Vitamin EVitamin E Icon AntioxidantAntioxidant Icon Helps brighten skinHelps brighten skin Icon

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

0 Com. / 0 Irr.
Triethylene Glycol Masking, Perfuming
Fragrance Icon
FragranceFragrance Icon

Triethylene Glycol is a fragrance.

Unknown Full details ->
BHT Antioxidant, Masking
Antioxidant Icon
AntioxidantAntioxidant Icon

BHT is a synthetic antioxidant. As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.

Very Disliked Full details ->
Propylene Glycol Humectant, Skin Conditioning, Solvent
0 / 0 May worsen Eczema Icon
May worsen EczemaMay worsen Eczema Icon

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

0 Com. / 0 Irr.
Disliked Full details ->

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Buffering, Masking
Loved

Azelaic acid is a naturally occurring acid derived from grains. This ingredient is effective in treating acne, rosacea, and other skin conditions.

It has been shown to reduce the growth of acne-causing bacteria and helps reduce inflammation. On top of that, it helps reduce the production of sebum and unclog pores.

Azelaic Acid also has antioxidant properties. Antioxidants protect our skin cells from free-radical damage.

One of the main benefits of azelaic acid is that it is gentle and well-tolerated by most people. It is also non-comedogenic, meaning that it will not clog pores.

Fun fact: The lab-created form of azelaic acid is typically used within cosmetic products for its shelf-stability.

Learn more about Azelaic Acid
Humectant, Skin Conditioning, Solvent
Disliked

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

Another role of this ingredient is preventing a product from melting or freezing. Propylene glycol also adds antimicrobrial properties to a product, elongating product lifespan.

This ingredient is considered an organic alcohol and commonly added into both cosmetics and foods.

Those with sensitive skin or conditions may deliver a rash when using this ingredient.

Learn more about Propylene Glycol
Disliked

Polyacrylamide is a synthetic polymer. It is used to stabilize products and bind ingredients. When hydrated, Polyacrylamide forms a soft gel.

Polyacrylamide is low-toxicity. If source properly, it is deemed safe to use in cosmetics.

It should be noted the precursor to Polyacrylamide is acrylamide. Acrylamide is a carcinogen. Most reputable sources of Polyacrylamide will screen for residual acrylamide to make sure the count is in a safe range. Acrylamide is not able to be absorbed through the skin.

We recommend speaking with a professional if you have concerns.

Learn more about Polyacrylamide
Emollient, Solvent
Very Disliked

C13-14 Isoparaffin is created from petroleum-based mineral oils. It is an emollient and helps thicken a product.

As an emollient, it helps keep the skin soft and smooth by creating a barrier on top. This barrier traps moisture in, keeping the skin hydrated.

C13-14 Isoparaffin may not be fungal-acne safe.

Learn more about C13-14 Isoparaffin
Emulsifying
Disliked

Laureth-7 is created by the ethoxylation of lauryl alcohol using ethylene oxide. Lauryl alcohol is a fatty alcohol with hydrating properties.

Laureth-7 is an emulsifier and cleansing ingredient. As an emulsifier, it is used to prevent ingredients from separating. It also helps cleanse the skin by gathering dirt, oil, and pollutants to be rinsed away.

Ingredient Ratings

Here's what our community thinks of the ingredients in these products.

Melazepam
2
16
1
liked
mixed
disliked
not rated
Custom Formula (Tretinoin 0.01% Azelaic acid 2% Niacinamide 4%)
6
1
6
1
liked
mixed
disliked
not rated

When to use

12 Routines
58% use in am
42% use in pm
75% use every day
14 Routines
0% use in am
100% use in pm
79% use every day