Gamma Chemicals Megaduo Plus
A facial treatment with 16 ingredients, including AHA, BHA, and retinoid.
Overview
What it is
Facial treatment with 16 ingredients that contains AHA, BHA, niacinamide and retinoid
Cool Features
It is vegan
Suited For
It has ingredients that are good for fighting acne, anti aging, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates
Fun facts
Gamma Chemicals is from Vietnam. This product is used in 5 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Water
Skin ConditioningHamamelis Virginiana Extract
AntiseborrhoeicCentella Asiatica Extract
CleansingPolysorbate 60
EmulsifyingLactic Acid
BufferingCetyl Alcohol
EmollientGlycolic Acid
BufferingManganese Chloride
Skin ConditioningDimethicone
EmollientPhenoxyethanol
PreservativeZinc Oxide
Cosmetic ColorantPyridoxine Hcl
Skin ConditioningNiacinamide
SmoothingRetinal
Skin ConditioningBisabolol
MaskingSalicylic Acid
MaskingKey Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterHamamelis Virginiana Extract comes from the witch hazel plant.
Unless it is specified to be non-alcohol, many types of witch hazel ingredients are distilled in denatured alcohol.
Witch Hazel has astringent, anti-inflammatory, antioxidant, and antibacterial properties.
The tannin content of witch hazel constrict the appearance of pores by drying out proteins. Witch hazel water gets anti-inflammatory and antibacterial properties from its catechin and gallic acid content.
However, witch hazel may be skin-sensitizing due to the tannin and fragrance compounds.
North American Indigenous groups have used witch hazel to help treat inflammation for centuries.
Learn more about Hamamelis Virginiana ExtractCentella Asiatica Extract (Centella) is derived from an herb native to Southeast Asia. It is famous for its anti-inflammatory and soothing properties.
Centella is rich in antioxidants and amino acids, such as Madecassic Acid and Asiaticoside.
Studies show the compounds in centella help with:
The combination of all these properties makes centella effective at soothing, hydrating, and protecting the skin.
Other great components of centella include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.
Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.
Learn more about Centella Asiatica ExtractPolysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.
Polysorbate 60 is sorbitol-based and created from the ethoxylation of sorbitan. Ethoxylation is a chemical reaction used to add ethylene oxide. Sorbitan is a the dehydrated version of sorbitol, a sugar found in fruits.
In this case, the 60 comes from reacting 60 units of ethylene oxide with sorbitan.
Polysorbates are commonly used in medicine and foods.
Learn more about Polysorbate 60Lactic Acid is another well-loved alpha hydroxy acid (AHA). It is gentler than glycolic acid but still highly effective.
Its main role is to exfoliate the surface of the skin by loosening the âglueâ that holds dead skin cells together. Shedding those old cells leads to smoother, softer, and more even-toned skin.
Because lactic acid molecules are larger than glycolic acid, they donât penetrate as deeply. This means theyâre less likely to sting or irritate, making it a great choice for beginners or those with sensitive skin.
Like glycolic acid, it can:
Lactic acid also acts as a humectant (like hyaluronic acid). It can draw water into the skin to improve hydration and also plays a role in the skin's natural moisturizing factor (NMF) in the form of sodium lactate.
Studies show it can boost ceramide production to strengthen the skin barrier and even help balance the skinâs microbiome.
To get results, choose products with a pH between 3-4.
Lower strengths (5-12%) focus on surface exfoliation; higher strengths (12% and up) can reach deeper in the dermis (deeper, supportive layer) to improve skin texture and firmness over time.
Though it was originally derived from milk, most modern lactic acid used in skincare is vegan. It is made through non-dairy fermentation to create a bio-identical and stable form suitable for all formulations.
Legend has it that Cleopatra used to bathe in sour milk to help reduce wrinkles.
Lactic acid is truly a gentle multitasker: it exfoliates, hydrates, strengthens, and brightens. It's a great ingredient for giving your skin a smooth, glowing, and healthy look without the harshness of stronger acids.
Read more about some other popular AHA's here:
Learn more about Lactic AcidCetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.
Its main roles are:
Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.
The FDA allows products labeled "alcohol-free" to have fatty alcohols.
Learn more about Cetyl AlcoholGlycolic Acid is arguably the most famous alpha hydroxy acid (AHA) with tons of research backing its benefits.
It is found naturally in sugar cane but the form used in skincare is usually synthetic for purity and stability.
Glycolic acid removes the top layer of dead skin cells to allow newer and fresher ones to emerge.
AHAs work by breaking down the structural âglueâ that holds old skin cells in place. When that buildup is gone, your skin can renew itself more efficiently.
Research also shows glycolic acid stimulates collagen production, helping to firm and thicken the skin over time. This is one of its biggest advantages over other AHAs.
Overall, glycolic acid helps with:
Fun fact: Glycolic acid boosts skin hydration by helping it produce molecules that increase hyaluronic acid naturally.
To work best, glycolic acid products should have a pH between 3-4 (thatâs where exfoliation is most effective but still gentle on skin).
The pH and concentration of a product are key to its effectiveness:
It is normal to feel a slight stinging sensation when using glycolic acid. This usually fades as your skin adjusts.
Because glycolic acid has the smallest molecular size in the AHA family, it can penetrate deeper, which enhances its effectiveness but also makes it more likely to irritate sensitive skin.
If your skin is very sensitive or prone to rosacea, glycolic acid may be too strong; in that case, try milder options like lactic acid or a PHA instead.
Recent studies suggest glycolic acid might even help protect against UV damage. But donât skip sunscreen! Freshly exfoliated skin is more sensitive to the sun.
Glycolic acid is a skincare superstar. It smooths, brightens, hydrates, and firms the skin. Unless youâre highly sensitive, itâs well worth adding to your routine.
Read more about some other popular AHA's here:
Learn more about Glycolic AcidWe don't have a description for Manganese Chloride yet.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconePhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Zinc Oxide is a mineral broad-spectrum UV filter; it is the broadest UVA and UVB reflector approved by the FDA. It also has skin protectant and skin soothing properties.
Zinc oxide is one of the most effective broad-spectrum UV filters. It protects against UVB, UVAII, and UVAI. In comparison to its counterpart titanium dioxide, zinc oxide provides uniform and extended UVA protection.
Another great benefit? This ingredient is highly photostable so it won't degrade easily under sunlight.
A common myth is that mineral UV filters are widely believed to primarily reflect UV light.
However, modern research shows titanium dioxide absorbs UV radiation like chemical filters (~95% absorption & 5% reflection).
Zinc oxide has great skin soothing properties so you'll likely find this in sunscreens formulated for sensitive skin or babies/children. It is unlikely to cause "eye sting" like other sunscreen ingredients.
Regulatory agencies consider zinc oxide to be non-toxic and safe. It has also been shown to not penetrate the skin.
Unfortunately, this ingredient does leave a visible white cast. This is why mineral sunscreens are often less cosmetically elegant than chemical or hybrid ones.
In cosmetics, zinc oxide can be found in both non-nano and nano-sized forms. The nano version is used to reduce white cast and improve the texture of sunscreen formulas.
There are ongoing concerns surrounding nano-zinc oxide's impact on marine ecosystems and whether it can be absorbed into skin.
Regarding marine ecosystems and coral reefs, there is no conclusive evidence that any form of zinc oxide (or any other sunscreen ingredients) will cause harm. The science is still developing but many consumers are keeping a close eye on this issue.
Please note, many destinations have reef-safety sunscreen rules. For instance, the U.S. Virgin Islands advises all visitors to use non-nano mineral sunscreens.
There has also been some stir about whether micronized or nano zinc oxide has potential photoxicity and absorption through the skin/lungs.
An in-vitro (done in a test tube or petri dish) study demonstrated micronized zinc oxide to have potential phototoxicity. There's no need to fret; the EU Commission's Scientific Committee on Consumer Safety has stated, "The relevance of these findings needs to be clarified by appropriate investigations in vivo." Or in other words, further studies done on living organisms are needed to prove this.
Current research shows zinc oxide nanoparticles do not penetrate intact or sunburned skin. They either remain on the surface or in the outermost layer of dead skin (stratum corneum).
Zinc oxide is one of only two classified mineral UV filters with titanium dioxide being the other one.
Fun fact: Zinc has been used throughout history as an ingredient in paint and medicine. An Indian text from 500BC is believed to list zinc oxide as a salve for open wound. The Ancient Greek physician Dioscorides has also mentioned the use of zinc as an ointment in 1AD.
Learn more about Zinc OxideWe don't have a description for Pyridoxine Hcl yet.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideRetinal is a form of retinoid. Retinoids are the gold-standard class of anti-aging ingredients.
Retinal has many benefits as other retinoids: improve skin texture, reduce large pores, reduce the effects of aging, reduce the visibility of dark spots, heal scars, and fight acne.
Studies show retinal may work at a faster rate than retinol due to its structure.
All retinoids have to be converted into retinoic acid before starting to work. Some retinoids take several steps of conversion before binding. Retinal is only one step away, making it more potent.
Like other retinoids, retinal may be irritating. It is best to ease into using this ingredient frequently.
Using the 'ramp up' method, start by using retinol once a week. This gives your skin time to adjust and decrease irritation. Once you feel ready, you can slowly increase the frequency of retinol use.
Using retinoids will increase sun-sensitivity in the first few weeks of use. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.
Learn more about RetinalBisabolol is famous for its skin soothing properties. It does this by blocking inflammatory signals, helping to reduce your body's reaction to irritation.
This ingredient also interferes with the process of hyperpigmentation. This can help with reducing dark spots and uneven tone.
Bisabolol is an antioxidant. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells. By fighting these free-radicals, Bisabolol may slow down signs of aging.
Studies have shown Bisabolol to have antimicrobial properties and may be a fungicide. These properties help preserve a product's shelf life.
All these properties makes bisabolol a great skin barrier helper ingredient.
Bisabolol also helps the absorption of other ingredients.
Note: Synthetic Bisabolol has been shown to be less effective.
Learn more about BisabololSalicylic Acid (also known as beta hydroxy acid or BHA) is a well-known ingredient for treating skin that struggles with acne and clogged pores. It exfoliates both the skin's surface and deep within the pores to help clear out buildup, control oil, and reduce inflammation.
Unlike AHAs (alpha hydroxy acids), salicylic acid is oil-soluble. This allows it to penetrate into pores which makes it especially effective for treating blackheads and preventing future breakouts.
Salicylic acid is also known for its soothing properties. It has a similar structure to aspirin and can calm inflamed or irritated skin, making it a good option for acne-prone skin that is also sensitive.
Concentrations of 0.5-2% are recognized by the U.S. FDA as an over-the-counter topical acne product.
It can cause irritation and/or dryness if one's skin already has a compromised moisture barrier, so it's best to focus on repairing that before introducing this ingredient into your routine.
While salicylic acid does not increase sun sensitivity, itâs still important to wear sunscreen daily to protect your skin.
If you are looking for the ingredient called BHA or Butylated Hydroxyanisole, click here.
Learn more about Salicylic AcidReviews
Where it's from
Gamma Chemicals is a Vietnamese brand
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The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Published March 17, 2025 • Added by quanminh