Angiopharm Antioxidant Defense Serum
A serum with 20 ingredients, including vitamin C, hyaluronic acid, and peptides.
Overview
What it is
Serum with 20 ingredients that contains hyaluronic acid, peptides and Vitamin C
Cool Features
It is reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores, scar healing and better texture
Free From
It doesn't contain any harsh alcohols, oils, parabens, silicones or sulfates
Fun facts
Angiopharm is from Russian Federation.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Water
Skin ConditioningGlycerin
HumectantPentylene Glycol
Skin ConditioningEthoxydiglycol
HumectantSodium Ascorbyl Phosphate
AntioxidantButylene Glycol
HumectantPhenoxyethanol
PreservativePolysorbate 20
EmulsifyingCellulose Gum
Emulsion StabilisingFerulic Acid
AntimicrobialCarnosine
Skin ConditioningLactic Acid
BufferingSh-Polypeptide-82
Skin ConditioningSodium Hyaluronate
HumectantResveratrol
AntioxidantAroma
Benzyl Salicylate
PerfumingLimonene
PerfumingDipropylene Glycol
HumectantEthylhexylglycerin
Skin ConditioningWater, Glycerin, Pentylene Glycol, Ethoxydiglycol, Sodium Ascorbyl Phosphate, Butylene Glycol, Phenoxyethanol, Polysorbate 20, Cellulose Gum, Ferulic Acid, Carnosine, Lactic Acid, Sh-Polypeptide-82, Sodium Hyaluronate, Resveratrol, Aroma, Benzyl Salicylate, Limonene, Dipropylene Glycol, Ethylhexylglycerin
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolEthoxydiglycol is a synthetic solvent.
Solvents are used to keep ingredients together in a product. They can help dissolve ingredients to stable bases or help evenly distribute ingredients throughout the product.
Ethoxydiglycol also helps deliver other key ingredients into the skin.
Learn more about EthoxydiglycolSodium Ascorbyl Phosphate (SAP) is a water-soluble form of Vitamin C. It is the salt of ascorbic acid.
This ingredient is commonly used in skincare because it's more formulation-stable while still offering the same benefits as pure ascorbic acid. Ascorbic acid is notorious for breaking down when exposed to sunlight and oxygen whereas SAP has been shown to be more stable.
Studies show SAP has anti-acne and antioxidant benefits. One study found 5% of SAP lotion to be an effective ingredient for treating acne vulgaris. This is because research shows that SAP may help control acne by reducing acne-causing bacteria and slowing the oxidation of skin oils caused by UV exposure.
In addition to acne, vitamin C is important for skin structure. Lab studies suggest SAP may support collagen production in skin cells, making it a great ingredient in anti-aging routines.
Vitamin C has many benefits: it helps reduce redness, improve skin texture, fade the appearance of dark spots, and brighten the skin.
Read more about other types of Vitamin C:
Learn more about Sodium Ascorbyl PhosphateButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Polysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.
It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.
The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.
Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).
True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.
Because it is derived from lauric acid, it may not be fungal acne safe.
Learn more about Polysorbate 20Cellulose Gum is a water-soluble polymer that comes from cellulose. It is used to change the texture of a product and to help stabilize emulsions.
As an emulsifier, cellulose gum specifically thicken the texture of water-based products.
This ingredient is considered hypoallergenic and non-toxic. Cellulose Gum can be found in cosmetics, food, and other household goods such as paper products.
Learn more about Cellulose GumFerulic Acid is a plant based antioxidant that can be naturally found in the cell walls of grains like rice, oats, and corn. It has antioxidant and antimicrobial properties, and has the ability to boost the performance of other antioxidants as well.
A well-known study found that adding Ferulic Acid to a solution of Vitamins C and E doubled the photoprotection of skin. This is why you'll often see it paired with Vitamin C or Vitamin E serums rather than sold on its own.
A 2025 review of 18 human studies found that using Ferulic Acid (0.5-1%) daily for one to three months showed improvements in:
As far as allergies go, Ferulic acid is generally well-tolerated but can cause an allergic reaction in very rare cases. It's also worth noting that Ferulic acid is often extracted from plant sources like rice bran or wheat bran, so be sure to path test if you have known grain allergies.
Outside of skincare, researchers are also looking into Ferulic Acid for its potential benefits in areas like diabetes, Alzheimer's, and heart health.
Learn more about Ferulic AcidCarnosine is a dipeptide made from two amino acids.
This ingredient helps:
Glycation is the process of sugars binding to and damaging proteins. Too much sugar in our skin can lead to damaged collagen, contributing to factors of aging.
Carnosine is water-soluble and is not able to travel deeper layers of skin. This leads to some doubt about whether it can boost collagen in skin, since collagen is located in the deeper layers of skin.
Fun fact: Carnosine can be naturally found in our muscles and brain.
Learn more about CarnosineLactic Acid is another well-loved alpha hydroxy acid (AHA). It is gentler than glycolic acid but still highly effective.
Its main role is to exfoliate the surface of the skin by loosening the âglueâ that holds dead skin cells together. Shedding those old cells leads to smoother, softer, and more even-toned skin.
Because lactic acid molecules are larger than glycolic acid, they donât penetrate as deeply. This means theyâre less likely to sting or irritate, making it a great choice for beginners or those with sensitive skin.
Like glycolic acid, it can:
Lactic acid also acts as a humectant (like hyaluronic acid). It can draw water into the skin to improve hydration and also plays a role in the skin's natural moisturizing factor (NMF) in the form of sodium lactate.
Studies show it can boost ceramide production to strengthen the skin barrier and even help balance the skinâs microbiome.
To get results, choose products with a pH between 3-4.
Lower strengths (5-12%) focus on surface exfoliation; higher strengths (12% and up) can reach deeper in the dermis (deeper, supportive layer) to improve skin texture and firmness over time.
Though it was originally derived from milk, most modern lactic acid used in skincare is vegan. It is made through non-dairy fermentation to create a bio-identical and stable form suitable for all formulations.
When lactic acid shows up near the end of an ingredient list, it usually means the brand added just a tiny amount to adjust the productâs pH.
Legend has it that Cleopatra used to bathe in sour milk to help reduce wrinkles.
Lactic acid is truly a gentle multitasker: it exfoliates, hydrates, strengthens, and brightens. It's a great ingredient for giving your skin a smooth, glowing, and healthy look without the harshness of stronger acids.
Read more about some other popular AHA's here:
Learn more about Lactic AcidSh-Polypeptide-82 is a peptide.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateResveratrol is a well-studied polyphenol antioxidant that has gained attention in skincare for its protective and calming effects on the skin. Itâs often considered a gentler option for people who canât tolerate retinoids.
This antioxidant is best known for its anti-aging benefits. Research suggests resveratrol helps combat visible signs of aging by:
Beyond anti-aging, resveratrol is also valued for its skin-brightening and soothing properties.
Some forms of resveratrol appear to be more effective than others. Resveratrol isobutyrate and resveratrol butyrate are often cited as more stable derivatives.
Research also suggests these two forms have stronger effects on Type I collagen stimulation and inflammation reduction compared to basic resveratrol.
Resveratrol is naturally unstable and can degrade when exposed to light and oxygen. Well-designed products often use stabilized derivatives, airless or opaque packaging, and supporting antioxidants to help maintain effectiveness on skin.
A note on resveratrol as a retinoid alternative:
While resveratrol offers antioxidant protection, inflammation control, and some collagen-supporting benefits, it does not replace retinoids in terms of cell turnover or acne treatment.
However, it can be a useful option for people with retinoid sensitivity or intolerance, or for those looking to support skin health without irritation.
Fun fact: Resveratrol is naturally found in grapes, peanuts, and berries, which is why itâs frequently associated with wine and grape-derived skincare ingredients.
Learn more about ResveratrolAroma refers to an ingredient, or mixture of ingredients, that impart or mask a flavor.
The name is slightly confusing. This is because INCI associates aroma with flavor instead of smell.
Here is the official definition from the The International Cosmetic Ingredient Dictionary and Handbook:
âAroma is a term for ingredient labeling used to identify that a product contains a material or combination of materials normally added to a cosmetic to produce or to mask a particular flavor.â
INCI shows the only purpose of aroma to be "flavouring".
However, due to regulation differences, some companies may use aroma in place of parfum.
In Canada, this ingredient only has to be listed in concentrations above 1%.
Learn more about AromaBenzyl Salicylate is a solvent and fragrance additive. It is an ester of benzyl alcohol and salicylic acid. This ingredient can be naturally found in some plants and plant extracts.
In fragrances, Benzyl Salicylate may be a solvent or a fragrance component. In synthetic musk scents, it is used as a solvent. For floral fragrances such as lilac and jasmine, it is used as a fragrance component. The natural scent of Benzyl Salicylate is described as "lightly-sweet, slightly balsamic".
While Benzyl Salicylate has been associated with contact dermatitis and allergies, emerging studies show it may not be caused by this ingredient alone.
However, this ingredient is often used with fragrances and other components that may cause allergies. It is still listed as a known allergen in the EU. We recommend speaking with a professional if you have concerns.
Another study from 2021 shows Benzyl Salicylate may have anti-inflammatory properties.
Learn more about Benzyl SalicylateLimonene is a fragrance that adds scent and taste to a formulation.
It's found in the peel oil of citrus fruits and other plants such as lavender and eucalyptus. The scent of limonene is generally described as "sweet citrus".
Limonene acts as an antioxidant, meaning it helps neutralize free radicals.
When exposed to air, oxidized limonene may sensitize the skin. Because of this, limonene is often avoided by people with sensitive skin.
The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.
Learn more about LimoneneDipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.
This ingredient helps:
Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the âgoodâ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.
As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.
Studies show Dipropylene Glycol is considered safe to use in skincare.
Learn more about Dipropylene GlycolEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinReviews
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Where it's from
Angiopharm is a Russian brand
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