Versus

Galderma Epiduo Versus Galderma Differin Cream

Prescription
Prescription
Swiss Brand Switzerland
Swiss Brand Switzerland

Updated on January 20, 2025

Overview

What they are

These products are both prescription. They have a total of 3 ingredients in common

Cool Features

They both contain retinoid

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing and better texture

Free From

They both do not contain any harsh alcohols, common allergens, fragrances, oils, silicones or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

Galderma Epiduo 12 ingredients

Galderma Differin Cream 10 ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Galderma Epiduo 12 ingredients

Galderma Differin Cream 10 ingredients

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Adapalene is a type of retinoid and common acne treatment.

It has been found to be as effective as other retinoids while causing less irritation.

Retinoids are the gold-standard for anti-aging due to the decades of research backing up their benefits:

You can buy adapalene over the counter, or in-store, in concentrations of 0.1% in gel form. 0.1% lotion or cream and 0.3% gel are only available with a prescription.

Learn more about Adapalene

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin

Ingredient Ratings

Here's what our community thinks of the ingredients in these products.

When to use

Galderma Epiduo 12 ingredients

Galderma Differin Cream 10 ingredients

102 Routines
5% use in am
95% use in pm
75% use every day
When to use See routines that use it ->
226 Routines
7% use in am
94% use in pm
73% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Galderma Epiduo 12 ingredients

4.0 /5
from 2 ratings
M31_12121181's avatar

M31_12121181

2 years ago
Review

Bye Acne
Very aggressive but very effective (Not as aggressive as the Clindoxyl). Benzoyl peroxide is no joke! I have used on my back acne and on the hormonal acne on my face, both worked perfectly. But never forget the moisturizer! Always follow the instructions written on the box and you will have no problems.

Galderma Differin Cream 10 ingredients

4.5 /5
from 4 ratings
Works Well (4) No Scent (3) Absorbs Well (2)
ChienYun_CY's avatar

Chien Yun Ang

9 months ago
Review

This cream is prescribed to me and I LOVE it. It isn't drying for me and I don't suffer any side effects from using it. I only need a fairly thin layer of this cream on my affected areas. It cleared up most possible developing whiteheads for me and leave my skin really bright and even.

#absorbs well
#no scent
#works well
Khang69's avatar

K

3 months ago
Review

I used this as a spot treatment for my stubborn/hidden acne and allergy pimples. It works great and the result might be visible after 1 or 2 days of use. The problem is it burned the area when I applied the cream with redness, it took weeks to get rid of the redness

#great value
#absorbs well
#no scent
#works well