What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Benzoyl Peroxide (BPO) is one of the most studied and widely used acne-fighting ingredients on the market for over five decades.
It works by releasing oxygen into your pores to kill Cutibacterium acne, or the bacteria closely linked to acne breakouts. This bacteria has a hard time surviving in an oxygen-rich environment.
On top of that, BPO has keratolytic properties to help shed dead skin cells and keep pores from getting clogged.
One of the coolest things about BPO is that bacteria do not develop resistance to it the way they can with antibiotics. That's why dermatologists recommend pairing it with topical antibiotics to keep resistance at bay.
BPO is usually available in 2.5%, 5%, and 10% concentrations. Research has shown that 2.5% tends to be just as effective as the higher strengths while being more gentle on the skin.
The FDA has classified BPO as a safe and effective acne treatment. You'll be able to find this ingredient in over-the-counter products in many countries.
Just so you know, BPO is a known mild irritant. It's common to see dryness, peeling, and some redness when you first start using it. This usually goes away as your skin adjusts.
A very small number of people might develop allergic contact dermatitis from it as patch test studies show positive reactions in about 1-5% of patients.
Once BPO is absorbed into the skin, our bodies turn it into benzoic acid and quickly exits in urine. It's also worth noting that BPO will bleach fabrics and hair, so watch your towels and pillowcases!
Learn more about Benzoyl PeroxideDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinIsohexadecane is added to enhance texture, emulsify, and to help cleanse. It is an isoparrafin. It is a component of petrolatum.
Due to its large size, Isohexadecane is not absorbed by the skin. Instead, it sits on top and acts as an emollient. Emollients help keep your skin soft and smooth by trapping moisture within.
Isohexadecane is often used in products designed to help oily skin. It is lightweight and non-greasy while helping to moisturize. When mixed with silicones, it gives a product a silky feel.
Learn more about IsohexadecaneWe don't have a description for Poloxamer 124 yet.
Polysorbate 80 is a surfactant and emulsifier. It is used to keep ingredients together, and prevent oils and waters from separating.
It is made from polyethoxylated sorbitan and oleic acid. This ingredient can be found in cosmetics, foods, and medicine. It is water-soluble.
Polysorbate 80 may not be fungal acne safe.
Learn more about Polysorbate 80Sodium Anisate comes from fennel. It is used as a preservative and to add flavoring.
Sodium Anisate has antimicrobial properties.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterAdapalene is a third-generation topical retinoid and is best known for treating mild to moderate acne. Itβs also commonly as for its brand name, Differin.
Adapalene has some great benefits:
You can buy over-the-counter adapalene at 0.1% gel strength. Higher concentrations require a prescription.
Oleyl adapalenate is a cosmetic-grade derivative of adapalene that does not require a prescription since it is considered a cosmetic ingredient.
Learn more about Adapalene
