Versus

Galderma Differin Cream Versus Obagi Tretinoin 0.05% Gel

Prescription
Prescription
Swiss Brand Switzerland
American Brand United States

Updated on January 20, 2025

Overview

What they are

These products are both prescription. They have a total of 4 ingredients in common

Suited For

They're both likely to be good for anti aging, dry skin and brightening skin

Free From

They both do not contain any oils, silicones or sulfates

What's Inside

They both contain parabens

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

Galderma Differin Cream 10 ingredients

Obagi Tretinoin 0.05% Gel 16 ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Galderma Differin Cream 10 ingredients

Obagi Tretinoin 0.05% Gel 16 ingredients

Key Ingredients

Benefits

Concerns

Benefits

Concerns

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Emulsion Stabilising, Gel Forming

Carbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Preservative

Propylparaben is a preservative and is a paraben with antifungal and antimicrobial properties.

This ingredient can be naturally found in plants and insects, but most of it is synthetically manufactured for human use. In cosmetics, it is usually created by reacting para-aminobenzoic acid and propanol (an alcohol).

You can usually find this ingredient in water-based products.

Parabens have come under controversy due to the claim they are hormone disruptors. Studies show conflicting results. We recommend speaking with a professional if you have any concerns.

Propylparaben is commonly found in food, medicine, and cosmetics.

Learn more about Propylparaben
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

When to use

Galderma Differin Cream 10 ingredients

Obagi Tretinoin 0.05% Gel 16 ingredients

226 Routines
7% use in am
93% use in pm
73% use every day
When to use See routines that use it ->
41 Routines
0% use in am
100% use in pm
85% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Galderma Differin Cream 10 ingredients

4.5 /5
from 4 ratings
Works Well (4) No Scent (3) Absorbs Well (2)
ChienYun_CY's avatar

Chien Yun Ang

9 months ago
Review

This cream is prescribed to me and I LOVE it. It isn't drying for me and I don't suffer any side effects from using it. I only need a fairly thin layer of this cream on my affected areas. It cleared up most possible developing whiteheads for me and leave my skin really bright and even.

#absorbs well
#no scent
#works well
Khang69's avatar

K

3 months ago
Review

I used this as a spot treatment for my stubborn/hidden acne and allergy pimples. It works great and the result might be visible after 1 or 2 days of use. The problem is it burned the area when I applied the cream with redness, it took weeks to get rid of the redness

#great value
#absorbs well
#no scent
#works well

Obagi Tretinoin 0.05% Gel 16 ingredients

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