Galderma Aklief Trifarotene Cream

Galderma Aklief Trifarotene Cream

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Overview

What it is

Prescription with 10 ingredients

Cool Features

It is fungal acne (malassezia) safe and reef safe

Suited For

It has ingredients that are good for dry skin, sensitive skin and scar healing

Free From

It doesn't contain any common allergens, fragrances, oils, parabens or sulfates

Fun facts

Galderma is from Switzerland. This product is used in 305 routines created by our community.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

What's inside

Benefits

Concerns

Ingredients Explained

This is not an INCI ingredient. It is a medicine used to treat acne vulgaris and is classified as a fourth generation retinoid.

This medicine is only available via doctor's prescription in the US, EU, Canada, and Australia.

We recommend speaking with your doctor about using this ingredient.

Learn more about Trifarotene
Skin Conditioning, Skin Protecting, Soothing

Allantoin is a soothing ingredient known for its protective and moisturizingg properties. Because of this, it is often added to products with strong active ingredients.

Studies show higher concentrations of this ingredient can promote wound healing.

Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity.

Learn more about Allantoin

We don't have a description for Acrylamide/Sodium Acryloyldimethyltaurate Copolymer yet.

Emollient, Skin Conditioning, Solvent

Isohexadecane is added to enhance texture, emulsify, and to help cleanse. It is an isoparrafin. It is a component of petrolatum.

Due to its large size, Isohexadecane is not absorbed by the skin. Instead, it sits on top and acts as an emollient. Emollients help keep your skin soft and smooth by trapping moisture within.

Isohexadecane is often used in products designed to help oily skin. It is lightweight and non-greasy while helping to moisturize. When mixed with silicones, it gives a product a silky feel.

Learn more about Isohexadecane
Emollient, Skin Conditioning, Solvent

Cyclomethicone is a class of silicones used to improve the texture of products.

Their cyclic or circular structure decreases stability. This causes quick evaporation when applied to skin. Cyclomethicones are often used as a carrier for other ingredients. Once it evaporates, it leaves a silky barrier on the skin.

The most popular types of cyclomethicones include D5 and D6.

Learn more about Cyclomethicone
Antimicrobial, Astringent, Masking

Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.

This ingredient gets a bad rep because it is irritating and drying - mostly due to its astringent property. Astringents draw out natural oils in tissue, constricting pores and leaving your skin dried out.

However, alcohol denat. is not all that bad.

Due to its low molecular weight, alcohol denat. tends to evaporate quickly. One study on pig skin found half of applied alcohol evaporated in 10 seconds and less than 3% stayed on skin.

This also helps other ingredients become better absorbed upon application.

Studies are conflicted about whether this ingredient causes skin dehydration. One study from 2005 found adding emollients to propanol-based sanitizer decreased skin dryness and irritation. Another study found irritation only occurs if your skin is already damaged.

Small amounts of alcohol are generally tolerated by oily skin or people who live in humid environments.

The rule of thumb is if this alcohol is near the end of an ingredients list, it will probably not affect your skin much.

Also...

This ingredient has antimicrobial and solvent properties.

The antimicrobial property helps preserve products and increase their shelf life. As a solvent, it helps dissolve other ingredients.

Other types of astringent alcohols include:

Learn more about Alcohol Denat.
Masking, Skin Conditioning

This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Humectant, Skin Conditioning, Solvent

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

Another role of this ingredient is preventing a product from melting or freezing. Propylene glycol also adds antimicrobrial properties to a product, elongating product lifespan.

This ingredient is considered an organic alcohol and commonly added into both cosmetics and foods.

Those with sensitive skin or conditions may develop a rash when using this ingredient.

Learn more about Propylene Glycol
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

Reviews

3.14
Overall rating
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2
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What people say
Drying 57% Expensive 43% Works Well 43%
7 reviews

Where it's from

Galderma is a Swiss brand

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Verified by SkinSort

We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.

The data we've presented on this page has been verified by a member of the SkinSort Team.

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ยท Updated July 5, 2025 Added by tabby_274