Safi Acne Solutions 3 in 1 Cica Acne Rescue Serum Versus Neutrogena Stubborn Blackheads Daily Acne Serum
Overview
What they are
These products are both fungal acne (malassezia) safe and reef safe serums. They have a total of 6 ingredients in common
Cool Features
They both contain AHA, BHA and PHA
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Safi Acne Solutions 3 in 1 Cica Acne Rescue Serum 17 ingredients
Neutrogena Stubborn Blackheads Daily Acne Serum 13 ingredients
What's inside
What's inside
At a glance
Click on any of the items below to learn more
Safi Acne Solutions 3 in 1 Cica Acne Rescue Serum 17 ingredients
Neutrogena Stubborn Blackheads Daily Acne Serum 13 ingredients
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningMandelic Acid
Antimicrobial
Methylpropanediol
SolventAminomethyl Propanol
BufferingSodium Hyaluronate
Humectant
Xanthan Gum
EmulsifyingDisodium EDTA
Gluconolactone
Skin Conditioning
Melia Azadirachta Leaf Extract
Skin ConditioningCitric Acid
Buffering
Propylene Glycol
Humectant
Lactic Acid
Buffering
Butylene Glycol
Humectant
Salicylic Acid
Masking
Centella Asiatica Leaf Extract
Skin Conditioning
Phenoxyethanol
Preservative
Sodium Metabisulfite
Antioxidant
Water, Mandelic Acid, Methylpropanediol, Aminomethyl Propanol, Sodium Hyaluronate, Xanthan Gum, Disodium EDTA, Gluconolactone, Melia Azadirachta Leaf Extract, Citric Acid, Propylene Glycol, Lactic Acid, Butylene Glycol, Salicylic Acid, Centella Asiatica Leaf Extract, Phenoxyethanol, Sodium Metabisulfite
Salicylic Acid 0.5%
Masking
Water
Skin ConditioningPropylene Glycol
Humectant
Glycolic Acid
Buffering
Dimethicone
Emollient
Mandelic Acid
Antimicrobial
Gluconolactone
Skin Conditioning
Sodium Hydroxide
BufferingNeopentyl Glycol Diheptanoate
EmollientHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingPolyacrylate Crosspolymer-6
Emulsion StabilisingDimethicone Crosspolymer
Emulsion Stabilising
Disodium EDTA
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.
Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.
Learn more about Disodium EDTAGluconolactone is a PHA. PHAs are a great gentle alternative to traditional AHAs.
When applied, Gluconolactone has the same affect on skin as AHAs such as lactic acid. It helps dissolve the dead skin cells in the top layer of your skin. This improves texture and brightens the skin.
PHAs are more gentle than AHAs due to their larger structure. They do not penetrate as deeply as AHAs and take a longer time to dissolve dead cells. Studies show PHAs do not cause as much irritation.
Gluconolactone has some interesting properties:
In a 2004 study, Gluconolactone was found to prevent UV damage in mouse skin cells and has not been found to increase sun sensitivity. However, we still recommend wearing SPF daily.
This ingredient is is an created by reacting gluconic acid with an alcohol.
Learn more about GluconolactoneMandelic Acid is an alpha hydroxy acid (AHA).
Like other AHAs, it helps exfoliate the surface of the skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
Mandelic acid helps with:
Due to it having a larger molecular size than glycolic acid, mandelic acid is able to penetrate the skin more slowly and evenly. This makes it gentler and less irritating, making it a great option for sensitive or beginner skin.
Despite being milder, mandelic acid is still an effective exfoliant that improves skin texture and tone over time.
What makes mandelic acid stand out from other AHAs? It has antibacterial and antioxidant properties.
These traits make it a great option for acne-prone or problem skin by reducing active breakouts and fading post-acne marks. Studies show that mandelic acid (especially when combined with salicylic acid) can significantly reduce pimples and hyperpigmentation while causing fewer side effects than stronger acids.
Mandelic acid is effective in concentrations of 5% and up with an ideal pH range of 3-4 for at-home use.
Like other AHAs, it’s important to wear sunscreen daily to protect your newly exfoliated skin.
However, unlike glycolic acid, mandelic acid is light-sensitive. Be sure your mandelic acid is packaged in opaque containers to ensure it stays stable and effective.
In short, mandelic acid is a gentle yet powerful AHA that exfoliates, brightens, and helps clarify skin while keeping irritation low. Its antibacterial action makes it especially beneficial for those with acne-prone, sensitive, or uneven skin, offering smoother, clearer, and more even-toned results over time.
Read more about some other popular AHA's here:
Learn more about Mandelic AcidPropylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.
Another role of this ingredient is preventing a product from melting or freezing. Propylene glycol also adds antimicrobrial properties to a product, elongating product lifespan.
This ingredient is considered an organic alcohol and commonly added into both cosmetics and foods.
Those with sensitive skin or conditions may develop a rash when using this ingredient.
Learn more about Propylene GlycolSalicylic Acid (also known as beta hydroxy acid or BHA) is a well-known ingredient for treating skin that struggles with acne and clogged pores. It exfoliates both the skin's surface and deep within the pores to help clear out buildup, control oil, and reduce inflammation.
Unlike AHAs (alpha hydroxy acids), salicylic acid is oil-soluble. This allows it to penetrate into pores which makes it especially effective for treating blackheads and preventing future breakouts.
Salicylic acid is also known for its soothing properties. It has a similar structure to aspirin and can calm inflamed or irritated skin, making it a good option for acne-prone skin that is also sensitive.
Concentrations of 0.5-2% are recognized by the U.S. FDA as an over-the-counter topical acne product.
It can cause irritation and/or dryness if one's skin already has a compromised moisture barrier, so it's best to focus on repairing that before introducing this ingredient into your routine.
While salicylic acid does not increase sun sensitivity, it’s still important to wear sunscreen daily to protect your skin.
If you are looking for the ingredient called BHA or Butylated Hydroxyanisole, click here.
Learn more about Salicylic AcidWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterIngredient Ratings
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When to use
Safi Acne Solutions 3 in 1 Cica Acne Rescue Serum 17 ingredients
Neutrogena Stubborn Blackheads Daily Acne Serum 13 ingredients
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Safi Acne Solutions 3 in 1 Cica Acne Rescue Serum 17 ingredients
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