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Overview

What they are

These products are both cruelty-free and reef safe serums. They have a total of 5 ingredients in common

Cool Features

They both contain peptides

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin and scar healing

Free From

They both do not contain any harsh alcohols, common allergens, parabens, silicones or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Mary & May 6 Peptide Complex Serum
Depology Matrixyl® 3000 Collagen Boosting Serum

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Benefits

Benefits

Concerns

Ingredients Side-by-side

found in both products
6 Peptide Complex Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Glycereth-26 Humectant
0 / 0

Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.

0 Com. / 0 Irr.
1,2-Hexanediol Skin Conditioning, Solvent

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Arginine Masking, Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.

Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Polyglyceryl-10 Laurate Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polyglyceryl-10 Laurate is an ester of lauric acid and Polyglycerin-10.

Very Disliked Full details ->
Adenosine Skin Conditioning
Helps with Anti-Aging IconGood for Scar Healing Icon
2 Benefits

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Caprylyl Glycol Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

Copper Tripeptide-1 Skin Conditioning
Peptide IconHelps with Anti-Aging Icon
PeptidePeptide Icon Helps with Anti-AgingHelps with Anti-Aging Icon

Copper Tripeptide-1 is a peptide naturally found in body fluids. Peptides are building blocks for protein.

Hexapeptide-11 Skin Conditioning
Peptide Icon
PeptidePeptide Icon

Hexapeptide-11 is a peptide.

Hexapeptide-9 Skin Conditioning
Peptide Icon
PeptidePeptide Icon

Hexapeptide-9 is a peptide.

Palmitoyl Pentapeptide-4 Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
PeptidePeptide Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

You might know this ingredients as Matrixyl. It is a peptide.

Palmitoyl Tripeptide-1 Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
PeptidePeptide Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Palmitoyl Tripeptide-1 is a 3-amino acid peptide. Peptides are building blocks for protein.

Tripeptide-1 Skin Conditioning, Skin Protecting
Peptide Icon
PeptidePeptide Icon

Tripeptide-1 is a peptide.

Matrixyl® 3000 Collagen Boosting Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Palmitoyl Pentapeptide-4 Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon
PeptidePeptide Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

You might know this ingredients as Matrixyl. It is a peptide.

Aloe Barbadensis Leaf Juice Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation Icon
2 Benefits

Aloe Barbadensis Leaf Juice comes from leaves of the aloe plant. Aloe Barbadensis Leaf Juice is best known for helping to soothe sunburns. It is also anti-inflammatory, moisturizing, antiseptic, and can help heal wounds.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Portulaca Oleracea Extract Skin Conditioning

Portulaca Oleracea Extract is an extract of the whole plant of the Purslane, Portulaca oleracea L., Portulacaceae. It has anti-inflammatory, antioxidant, and hydrating properties.

Hyaluronic Acid Humectant, Moisturising, Skin Conditioning
Hyaluronic Acid IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation Icon
Hyaluronic AcidHyaluronic Acid Icon 4 Benefits May cause irritationMay cause irritation Icon

Hyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.

Codium Tomentosum Extract Skin Protecting

We don't have a description for Codium Tomentosum Extract.

Unknown Full details ->
Citrus Paradisi Seed Extract Masking, Perfuming
Fragrance Icon
FragranceFragrance Icon

Citrus Paradisi Seed Extract is a fragrance.

Unknown Full details ->
Cereus Grandiflorus Extract Antioxidant, Astringent, Skin Conditioning
Antioxidant Icon
AntioxidantAntioxidant Icon

Cereus Grandiflorus Extract is an antioxidant.

Unknown Full details ->
Polyglyceryl-6 Caprylate Emulsifying

Polyglyceryl-6 Caprylate comes from caprylic acid and Polyglycerin-6. It is an emulsifier, emollient, and cleansing agent.

Unknown Full details ->
Trehalose Humectant, Moisturising

Trehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.

Hydroxyacetophenone Antioxidant
Antioxidant Icon
AntioxidantAntioxidant Icon

Hydroxyacetophenone is antioxidant and helps with skin conditioning.

1,2-Hexanediol Skin Conditioning, Solvent

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

Cocos Nucifera Oil Masking, Perfuming, Skin Conditioning
4 / 0 Fragrance IconOil IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon
FragranceFragrance Icon OilOil Icon 2 Concerns

Cocos Nucifera Oil is obtained from the kernels of the coconut fruit. In other words, this is coconut oil.

4 Com. / 0 Irr.
Very Disliked Full details ->
Rosa Canina Fruit Oil Emollient, Skin Conditioning
Oil IconGood for Scar Healing IconNot safe for Fungal Acne Icon
OilOil Icon Good for Scar HealingGood for Scar Healing Icon Not safe for Fungal AcneNot safe for Fungal Acne Icon

Rosehip Oil is a nonfragrant plant oil. Rosehips are a fruit from a rose bush and are edible. This oil helps even out skin tone, has anti-aging properties, and is good for reducing inflammation.

Helianthus Annuus Seed Oil Emollient, Masking, Skin Conditioning
0 / 0 Oil IconHelps hydrate Dry Skin IconMay worsen Oily Skin IconNot safe for Fungal Acne Icon
OilOil Icon Helps hydrate Dry SkinHelps hydrate Dry Skin Icon 2 Concerns

Helianthus Annuus Seed Oil is the oil derived from the seeds of a Sunflower. Sunflower seed oil is non-fragrant. It is an emollient, meaning it helps to soften the skin.

0 Com. / 0 Irr.
Disliked Full details ->
Allantoin Skin Conditioning, Skin Protecting, Soothing
0 / 0 Helps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon
3 Benefits

Allantoin plays a role in soothing and moisturizing the skin. Because of this, it is often added to products with strong active ingredients.

0 Com. / 0 Irr.
Stearic Acid Cleansing, Emulsifying, Emulsion Stabilising
2-3 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon
2 Concerns

Stearic Acid is a fatty acid. It is an emollient, emulsifier, and texture enhancer.

2-3 Com. / 0 Irr.
Very Disliked Full details ->
Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Skin Conditioning, Solvent
Mixed

1,2-Hexanediol is a multi-tasker ingredient. It acts as a preservative to increase shelf-life and can aid other preservatives in preventing microbe growth. 1,2-Hexanediol also helps the skin retain moisture as a humectant.

In products that are water-based, this ingredient can help stabilize perfumes and fragrances. It can also help make the texture of products softer and more smooth.

Humectant, Masking, Skin Conditioning
Mixed

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.

Overall, Butylene Glycol is a safe and well-rounded ingredient. It is unlikely to irritate skin, and works well with pretty much all other ingredients.

Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Skin Conditioning
Loved

You might know this ingredients as Matrixyl. It is a peptide.

Peptides are building blocks for protein. Palmitoyl Pentapeptide-4 consists of five amino acids. These amino acids include: 2 lysines, 2 threonines, and serine

This ingredients tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.

Thus, Matrixyl may help improve the look of wrinkles.

Read more about other common types of peptides here:

Learn more about Palmitoyl Pentapeptide-4

Ingredient Ratings

Here's what our community thinks of the ingredients in these two products.

6 Peptide Complex Serum
11
4
2
liked
mixed
disliked
not rated
Matrixyl® 3000 Collagen Boosting Serum
9
3
4
4
liked
mixed
disliked
not rated

When to use

78 Routines
33% use in am
67% use in pm
85% use every day
When to use See routines that use it ->
19 Routines
32% use in am
68% use in pm
100% use every day

Reviews

Here's what our community thinks

Mary & May 6 Peptide Complex Serum 17 ingredients

4.0 /5
from 2 ratings

Depology Matrixyl® 3000 Collagen Boosting Serum 20 ingredients

5.0 /5
from 1 rating
Nanciel's avatar

Nanciel

8 months ago · Sensitive Skin
Review

Absorbs nicely removed my wrinkles in between brows