What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Tretinoin 0.05%
Skin Conditioning
Polyethylene
Abrasive
Glycol Stearate
Emollient
Glyceryl Stearate
Emollient
PEG-100 Stearate
Surfactant
Cetyl Alcohol
Emollient
Stearyl Alcohol
Emollient
Squalane
Emollient
BHA
Antioxidant
BHT
Antioxidant
Propylparaben 0.05%
Preservative
Stearic Acid
Cleansing
Carbomer
Emulsion StabilisingGlycerin
Humectant
Methylparaben 0.1%
Preservative
Disodium EDTA
Triethanolamine
BufferingIsopropyl Myristate
Emollient
Sorbic Acid 0.2%
Preservative
Water
Skin ConditioningIngredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
BHT is a synthetic antioxidant and preservative.
As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.
As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.
The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.
However, it was recently restricted for use in the UK as of April 2024.
Learn more about BHTIsopropyl Myristate is an ester made by combining isopropyl alcohol with myristic acid.
It is primarily an emollient and penetration enhancer that gives products a lightweight, silky feel without the heaviness of oils.
This ingredient is generally considered non-toxic, non-irritating, and has low absorption potential.
You might have heard that this ingredient clogs pores. This reputation comes from the older rabbit ear studies which are more sensitive than human skin to clogging.
Dermatologist Dr. Zoe Draelos has also confirmed in a peer-reviewed paper that products containing comedogenic ingredients are not necessarily comedogenic themselves.
A small subset of people (~2%) may experience contact sensitivity so patch testing is a reasonable idea if you have reactive skin.
Since this ingredient is an ester of myristic acid (a C14 fatty acid), it falls within the carbon chain range that is known to feed Malassezia. This ingredient may not be fungal acne safe.
Learn more about Isopropyl MyristateSorbic Acid is a preservative that stops your product from spoiling by stopping microbes from growing.
As a preservative, it's kind of a specialist: it has a broad spectrum of activity against yeast and molds but is weaker against bacteria. That's why it's often paired with another preservative to cover that gap.
This ingredient is also pretty picky about pH; it performs best at pH 6.5 or below.
At the right pH level, sorbic acid is "active" and can slip through the outer wall of a microbe. Once inside, it turns the cell's interior more acidic to shut down the microbe from the inside.
The EU caps this ingredient at 0.6% while the CIR has concluded it's safe at concentrations up to 1%. It's most often used around 0.05-0.2% in cosmetics.
Though this ingredient is considered low-sensitizing and well-tolerated, a very small number of people may have a contact allergy to it. Be sure to patch test if you have a history of allergies towards preservatives.
Learn more about Sorbic AcidStearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.
In cosmetics, it is a multitasker:
Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.
Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.
Learn more about Stearic AcidStearyl Alcohol is a type of fatty alcohol from stearic acid. It is a white, waxy compound used to emulsify ingredients used as an emollient or to thicken a product.
Emollients help soothe and hydrate the skin by trapping moisture.
Fatty alcohols are usually derived from natural fats and oils and therefore do not have the same drying or irritating effect as solvent (ethanol) alcohols.
The FDA allows products labeled "alcohol-free" to have fatty alcohols.
This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.
Learn more about Stearyl AlcoholWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterTretinoin (aka retinoic acid) is the gold standard retinoid in dermatology because it's the form of vitamin A that your skin can use right away. It's a prescription drug and regulated as medication in most countries.
Unlike retinol, it skips the conversion steps and goes straight to work.
Inside your skin cells, it binds to receptors called retinoic acid receptors and switches on the genes that control how skin cells behave.
For acne, it helps your skin shed dead cells properly instead of letting them build up and clog your pores (this is what turns into blackheads and pimples). It also calms redness/swelling, which is why it's a FDA-approved acne treatment.
Tretinoin also tells your skin to make more collagen and slows down the stuff that breaks collagen apart too. Over time, your skin looks smoother, softer, and more even, with fewer lines lines and sun spots.
The evidence for this ingredient is strong:
A systematic review of randomized controlled trials found that topical tretinoin consistently improved wrinkles, pigmentation, sallowness, and dark spots. Results typically showed up as early as one month and lasted out to 24 months.
All studies also found this ingredient to be safe and well-tolerated.
Typical concentrations run from about 0.01-0.1%, with 0.025%-0.1% being the usual range studied for photoaging and a 0.05% cream producing measurable wrinkle/roughness improvements in large six-month trials.
The main trade-off is irritation; dryness, peeling, redness, and sun sensitivity are common in the first few weeks so be sure to pair it well with a good moisturizer and daily sunscreen.
Learn about a form of retinoid you can purchase at the store, retinol.
Learn more about Tretinoin
