Avène RetrinAL 0.1 Intensive Cream Versus Differin Adapalene Gel 0.1% Acne Treatment
Updated on May 19, 2025
Overview
What they are
These products are both facial treatments. They have a total of 2 ingredients in common
Cool Features
They both contain retinoid
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, oily skin, reducing pores, scar healing and better texture
Free From
They both do not contain any harsh alcohols, common allergens, fragrances or sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Avène RetrinAL 0.1 Intensive Cream 25 ingredients
Differin Adapalene Gel 0.1% Acne Treatment 8 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
Avène RetrinAL 0.1 Intensive Cream 25 ingredients
Differin Adapalene Gel 0.1% Acne Treatment 8 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Triethylhexanoin
MaskingCyclopentasiloxane
Emollient
Cetearyl Alcohol
Emollient
Cyclohexasiloxane
Emollient
Ceteareth-20
Cleansing
Polymethyl Methacrylate
Ceteareth-33
CleansingCaprylic/Capric Triglyceride
Masking
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Oenothera Biennis Oil
Emollient
Phenoxyethanol
Preservative
Benzoic Acid
Masking
Disodium EDTA
Retinal
Skin Conditioning
Tocopheryl Glucoside
EmollientOleoyl Dipeptide-15
Skin Conditioning
Mica
Cosmetic Colorant
Sodium Hydroxide
BufferingSilica
Abrasive
BHT
Antioxidant
Oleoyl Tetrapeptide-31
Antioxidant
Tocopherol
Antioxidant
Titanium Dioxide
Cosmetic Colorant
Caramel
Cosmetic ColorantCI 17200
Cosmetic ColorantTriethylhexanoin, Cyclopentasiloxane, Cetearyl Alcohol, Cyclohexasiloxane, Ceteareth-20, Polymethyl Methacrylate, Ceteareth-33, Caprylic/Capric Triglyceride, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Oenothera Biennis Oil, Phenoxyethanol, Benzoic Acid, Disodium EDTA, Retinal, Tocopheryl Glucoside, Oleoyl Dipeptide-15, Mica, Sodium Hydroxide, Silica, BHT, Oleoyl Tetrapeptide-31, Tocopherol, Titanium Dioxide, Caramel, CI 17200
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.
Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.
Learn more about Disodium EDTASodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideIngredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Avène RetrinAL 0.1 Intensive Cream 25 ingredients
Differin Adapalene Gel 0.1% Acne Treatment 8 ingredients
Reviews
Here's what our community thinks
Avène RetrinAL 0.1 Intensive Cream 25 ingredients
Differin Adapalene Gel 0.1% Acne Treatment 8 ingredients
Honestly I was skeptical because it took my skin the FULL 12+ weeks to adjust to this. It was my first time using a retinoid and the purging was rough, but genuinely I’ve never seen my skin look so good after the purging ended. It absorbs well and a little goes a long way. I had to stop using it because I got too crazy with actives and I messed up my skin barrier super bad, but I’m hoping I can go Show more
Don’t give up on this product. After suffering a sudden and severe breakout three months ago, I started on Differin in combination with a few other treatments. The first 8 weeks were hard, but in combination with a few other acne treatments, my skin has improved SO MUCH. I am on week 11 and am so glad I stuck it out with Differin. Looking forward to seeing continued improvement.
