Dermaquest Niacinamide Serum
A serum that contains hyaluronic acid, niacinamide, peptides and vitamin c.
Overview
What it is
Serum with 23 ingredients that contains hyaluronic acid, niacinamide, peptides and Vitamin C
Cool Features
It is reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, parabens, silicones or sulfates
Fun facts
Dermaquest is from United States. This product is used in 2 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside (and what isn't)
Ingredients List
Dive into the full list of ingredients.
Water
Skin ConditioningGlycerin
HumectantNiacinamide
SmoothingPEG-8/Smdi Copolymer
Polysorbate 20
EmulsifyingAcetyl Hexapeptide-8
HumectantPalmitoyl Hexapeptide-52
Skin ConditioningPassiflora Incarnata Extract
AstringentCamellia Sinensis Extract
AntioxidantCyperus Papyrus Leaf Cell Extract
AntioxidantSodium Hyaluronate
HumectantHydrolyzed Sodium Hyaluronate
Skin ConditioningSodium Ascorbyl Phosphate
AntioxidantButylene Glycol
HumectantCarbomer
Emulsion StabilisingPalmitoyl Pentapeptide-4
Skin ConditioningEthylhexylglycerin
Skin ConditioningCitric Acid
BufferingPotassium Sorbate
PreservativePhenoxyethanol
PreservativeSodium Lactate
BufferingLavandula Angustifolia Oil
MaskingLinalool
PerfumingWater, Glycerin, Niacinamide, PEG-8/Smdi Copolymer, Polysorbate 20, Acetyl Hexapeptide-8, Palmitoyl Hexapeptide-52, Passiflora Incarnata Extract, Camellia Sinensis Extract, Cyperus Papyrus Leaf Cell Extract, Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Sodium Ascorbyl Phosphate, Butylene Glycol, Carbomer, Palmitoyl Pentapeptide-4, Ethylhexylglycerin, Citric Acid, Potassium Sorbate, Phenoxyethanol, Sodium Lactate, Lavandula Angustifolia Oil, Linalool
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideWe don't have a description for PEG-8/Smdi Copolymer yet.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.
Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.
The lauric acid used to create Polysorbate 20 is often derived from coconuts.
Polysorbate 20 may not be fungal acne safe.
Learn more about Polysorbate 20Acetyl Hexapeptide-8 is a peptide. A common name for this peptide is Argireline.
Argireline has a similar function to botox; it prevents muscle movement and contractions slightly. By preventing muscles from moving, argireline also prohibits the formation of fine lines and wrinkles. However, research is lacking in proving this ingredient to be as effective as botox.
On the other hand, argireline tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Read more about other common types of peptides here:
Learn more about Acetyl Hexapeptide-8Palmitoyl Hexapeptide-52 isn't fungal acne safe and is a peptide.
We don't have a description for Passiflora Incarnata Extract yet.
Camellia Sinensis Extract is from the oil in tea plant leaves. The leaves give us various types of tea: green, black, oolong, and white.
Camellia Sinensis leaves have many benefits. It contains polyphenols, a strong antioxidant. Antioxidants help fight off free-radical molecules that damage skin cells. The antioxidants in green tea neutralize free-radicals from the sun. This gives the skin some extra UV protection, but should not replace sunscreen.
Many components of tea have anti-inflammatory and antimicrobial properties. Polyphenols and L-theanine help soothe the skin and reduce irritation. L-theanine is an amino acid that makes up most of the amino acids found in tea leaves. The caffeine in Camellia Sinensis Leaf Extract helps calm inflamed blood vessels.
Tea leaves also contain Vitamin Bs, linoleic acid, magnesium, calcium, iron, and zinc.
Research has shown both drinking Camellia Sinensis Leaf Tea and applying it to the skin can help boost skin elasticity and hydration. Studies also show using tea extract may reduce sebum, or oil, production.
Learn more about Camellia Sinensis ExtractCyperus Papyrus Leaf Cell Extract is an antioxidant.
Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateThis ingredient is created by putting sodium hyaluronate through hydrolysis.
You might know this as 'mini' or 'ultra low-molecular weight' hyaluronic acid. The small molecule size means it is able to travel deeper in the skin.
According to studies, low molecular-weight hyaluronic acid can:
One study from 2011 found ultra-low weight HA to show pro-inflammatory properties. Another study from 2022 found it to downregulate UV-B induced inflammation.
Hydrolysis is a process of changing a molecule using water or enzymes.
This ingredient is water-soluble.
Learn more about Hydrolyzed Sodium HyaluronateSodium Ascorbyl Phosphate is a form of Vitamin C. It is the salt of ascorbic acid.
This ingredient is more gentle than ascorbic acid. It is also more stable when exposed to light and oxygen.
Vitamin C helps reduce redness, improve skin texture, reduce the effects of aging, reduce the visibility of dark spots, and brighten skin.
Your skin uses Vitamin C to produce collagen and collagen production plays a role in having a strong skin barrier and plump skin. As an antioxidant, this ingredient also helps reduce the signs of aging such as fine-lines and wrinkles.
VItamin C helps brighten skin by blocking the process of skin darkening.
In a 2011 study, Sodium Ascorbyl Phosphate was found to have antibacterial properties. This may help treat acne.
Read more about other types of Vitamin C:
Learn more about Sodium Ascorbyl PhosphateButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCarbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.
A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.
You might know this ingredients as Matrixyl, a famous peptide.
Peptides are building blocks for protein. Palmitoyl Pentapeptide-4 consists of five amino acids. These amino acids include: 2 lysines, 2 threonines, and serine
This ingredients tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Thus, Matrixyl may help improve the look of wrinkles.
Read more about other common types of peptides here:
Learn more about Palmitoyl Pentapeptide-4Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).
As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and even out skin tone.
If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.
Read more about some other popular AHA's here:
Learn more about Citric AcidPotassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Learn more about Potassium SorbatePhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Sodium Lactate is the sodium salt of lactic acid, an AHA. It is a humectant and sometimes used to adjust the pH of a product.
This ingredient is part of our skin's NMF, or natural moisturizing factor. Our NMF is essential for the hydration of our top skin layers and plasticity of skin. NMF also influences our skin's natural acid mantle and pH, which protects our skin from harmful bacteria.
High percentages of Sodium Lactate can have an exfoliating effect.
Fun fact: Sodium Lactate is produced from fermented sugar.
Learn more about Sodium LactateLavandula Angustifolia Oil is more commonly known as lavender essential oil. It is considered a fragrancing ingredient.
Lavender imparts a famous scent. While the smell is lovely, this ingredient and may sensitize skin in topical products. This is because about 85% of the oil is made up of linalool and linalyl acetate.
When exposed to air, these two compounds become strong allergens. This ingredient exhibits cytotoxicity at low concentrations; amounts of 0.25% have been shown to damage skin cells.
A study from Japan found this ingredient caused lavender sensitivity after widespread exposure.
Lavender essential oil has some antimicrobial, antibacterial, and anti-inflammatory properties. However, the cons of this ingredient may outweight the pros.
More research is needed to confirm lavender essential oil's effects when used in aromatherapy.
Lavandula Angustifolia is known as the English Lavender and famous for creating purple fields in Provence, France.
Learn more about Lavandula Angustifolia OilLinalool is a fragrance and helps add scent to products. It's derived from common plants such as cinnamon, mint, citrus, and lavender.
Like Limonene, this ingredient oxidizes when exposed to air. Oxidized linalool can cause allergies and skin sensitivity.
This ingredient has a scent that is floral, spicy tropical, and citrus-like.
Learn more about LinaloolReviews
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Where it's from
Dermaquest is a American brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated March 10, 2025 • Added by aimeekeene