Versus

Galderma Retacnyl Tretinoin Cream 0.05% Versus Menarini Tretinoin Gel 0.05%

Prescription
Prescription
Swiss Brand Switzerland
Italian Brand Italy

Updated on April 16, 2025

Overview

What they are

These products are both prescription. They have a total of 5 ingredients in common

Cool Features

They both contain exfoliants and retinoid

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any harsh alcohols, common allergens, fragrances, silicones or sulfates

What's Inside

They both contain parabens

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning

Tretinoin is the best retinoid due to its proven skin benefits. It only available with a prescription in many countries.

All retinoids goes through a conversion line until it can become effective. The final step of conversion is retinoic acid; retinoic acid IS Tretinoin.

This is why tretinoin is so effective; it gets to work immediately on the skin.

Research on tretinoin has found it to be incredibly effective for reducing the signs of aging. It helps improve damage from the sun, even the skin tone, and smooth out wrinkles. It is also an effective acne treatment by reducing and balancing out sebum production in pores.

Tretinoin, like other forms of Vitamin A, increases the turnover cycle of skin cells. This helps the skin create newer and healthier skin cells faster.

It can cause irritation, redness, and dry skin because it is considered a "strong" ingredient. Those with sensitive skin should consult a professional about using tretinoin.

Using retinoids will increase sun-sensitivity in the first few weeks of use. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

Read about a form of retinoid you can purchase at the store, retinol.

Learn more about Tretinoin
Preservative

Propylparaben is a preservative and is a paraben with antifungal and antimicrobial properties.

This ingredient can be naturally found in plants and insects, but most of it is synthetically manufactured for human use. In cosmetics, it is usually created by reacting para-aminobenzoic acid and propanol (an alcohol).

You can usually find this ingredient in water-based products.

Parabens have come under controversy due to the claim they are hormone disruptors. Studies show conflicting results. We recommend speaking with a professional if you have any concerns.

Propylparaben is commonly found in food, medicine, and cosmetics.

Learn more about Propylparaben
Emulsion Stabilising, Gel Forming

Carbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

Buffering, Emulsifying, Masking

Triethanolamine is an emulsifier and pH adjuster. It is created using ethylene oxide and ammonia. This gives Triethanolamine a nitrogen core and a similar scent to ammonia.

As an emulsifier, it prevents ingredients from separating and enhances texture by adding volume to a product.

PH adjusters are common in cosmetic products. The pH of a product can affect the effectiveness of other ingredients. A product with a high pH may also irritate the skin.

Learn more about Triethanolamine
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

8 Routines
0% use in am
100% use in pm
88% use every day
241 Routines
1% use in am
99% use in pm
69% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Galderma Retacnyl Tretinoin Cream 0.05% 20 ingredients

Retacnyl Tretinoin Cream 0.05% hasn't been rated yet.
Rate it now

Menarini Tretinoin Gel 0.05% 11 ingredients

5.0 /5
from 3 ratings
Drying (1) Great Value (1) Works Well (1)
SailorMoon_954's avatar

SailorMoon_954

1 year ago
Review

help with my acne but drying

melisytee's avatar

melisa

1 month ago
Review

It is amazing for acne. I had forehead acne where it was cysts, comedies, fungal acne. It went all away using this. I had deep rooted scarring and hyperpigmentation marks and scars and this helped heal it all. Problem is you can burn yourself if you don’t use it sparingly, in a consistent routine. It also is very very drying so you need to moisture a lot. It also causes ur skin to flake as this Show more

#great value
#drying
#works well