Updated on September 11, 2023
Overview
What they are
These products are both cruelty-free and reef safe serums. They have a total of 6 ingredients in common
Cool Features
They both contain ceramides, hyaluronic acid, niacinamide and peptides
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots
Free From
They both do not contain any harsh alcohols, common allergens, oils, parabens or silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
DRMTLGY Needle-Less Serum 29 ingredients
Le Mieux TGF-B Booster 32 ingredients
About this product
About this product
At a glance
Click on any of the items below to learn more
DRMTLGY Needle-Less Serum 29 ingredients
Le Mieux TGF-B Booster 32 ingredients
Key Ingredients
Benefits
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
Humectant
Sodium Chondroitin Sulfate
Skin Conditioning
Sodium Hyaluronate
Humectant
Pisum Sativum Extract
Skin ConditioningBambusa Vulgaris Leaf/Stem Extract
HumectantPalmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Ceramide EOP
Skin Conditioning
Glucosamine Hcl
Glycosaminoglycans
EmollientCeramide NP
Skin Conditioning
Palmitoyl Tripeptide-5
Skin Conditioning
Ceramide AP
Skin Conditioning
Phytosphingosine
Skin Conditioning
Cholesterol
Emollient
Niacinamide
Smoothing
Sodium Lauroyl Lactylate
EmulsifyingMethylglucoside Phosphate
Skin ConditioningCopper Lysinate/Prolinate
Skin ConditioningPanthenol
Skin Conditioning
Tocopheryl Acetate
Antioxidant
Phenoxyethanol
Preservative
Polysorbate 20
Emulsifying
Ethylhexylglycerin
Skin ConditioningDisodium EDTA
Butylene Glycol
Humectant
Carbomer
Emulsion StabilisingXanthan Gum
EmulsifyingWater, Glycerin, Sodium Chondroitin Sulfate, Sodium Hyaluronate, Pisum Sativum Extract, Bambusa Vulgaris Leaf/Stem Extract, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP, Glucosamine Hcl, Glycosaminoglycans, Ceramide NP, Palmitoyl Tripeptide-5, Ceramide AP, Phytosphingosine, Cholesterol, Niacinamide, Sodium Lauroyl Lactylate, Methylglucoside Phosphate, Copper Lysinate/Prolinate, Panthenol, Tocopheryl Acetate, Phenoxyethanol, Polysorbate 20, Ethylhexylglycerin, Disodium EDTA, Butylene Glycol, Carbomer, Xanthan Gum
Hyaluronic Acid
Humectant
Hydrolyzed Sodium Hyaluronate
Skin ConditioningSodium Hyaluronate
Humectant
Sodium Hyaluronate Crosspolymer
Humectant
Hydroxypropyltrimonium Hyaluronate
C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate
Superoxide Dismutase
Antioxidant
Saccharomyces Polypeptides
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Palmitoyl Tripeptide-5
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Acetyl Octapeptide-3
Humectant
Ceramide Ns
Skin Conditioning
Saccharomyces/Copper Ferment
Skin ConditioningSaccharomyces/Zinc Ferment
Skin ConditioningSaccharomyces/Manganese Ferment
Skin ConditioningRiboflavin
Cosmetic ColorantPhospholipids
Skin ConditioningFolic Acid
Skin ConditioningEnteromorpha Compressa Extract
Skin ProtectingGlycoproteins
Skin Conditioning
Ginkgo Biloba Leaf Extract
Skin ConditioningSerine
MaskingProline
Skin ConditioningAlanine
MaskingGlutamic Acid
HumectantNiacinamide
Smoothing
Parfum
Masking
Caprylyl Glycol
EmollientEthylhexylglycerin
Skin ConditioningUndecylenoyl Glycine
CleansingCapryloyl Glycine
CleansingHyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Hydroxypropyltrimonium Hyaluronate, C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate, Superoxide Dismutase, Saccharomyces Polypeptides, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-5, Palmitoyl Tripeptide-1, Acetyl Octapeptide-3, Ceramide Ns, Saccharomyces/Copper Ferment, Saccharomyces/Zinc Ferment, Saccharomyces/Manganese Ferment, Riboflavin, Phospholipids, Folic Acid, Enteromorpha Compressa Extract, Glycoproteins, Ginkgo Biloba Leaf Extract, Serine, Proline, Alanine, Glutamic Acid, Niacinamide, Parfum, Caprylyl Glycol, Ethylhexylglycerin, Undecylenoyl Glycine, Capryloyl Glycine
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronatePalmitoyl Tripeptide-1 is a 3-amino acid peptide. Peptides are building blocks for protein.
This ingredient is a signal peptide, meaning it tells our skin to create collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Palmitoyl Tripeptide-1 can help reduce wrinkles and make the skin look more youthful.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tripeptide-1Palmitoyl Tetrapeptide-7 is a peptide. Peptides are building blocks for protein.
This ingredient consists of four amino acids and palmitic acid. These amino acids are arginine, proline, glutamine, and glycine.
This ingredient has many benefits. These benefits include boosting collagen production, fighting inflammation, and reversing UV damage.
By preventing our bodies from producing interleukins, Palmitoyl Tetrapeptide-7 helps fight inflammation. An interleukin is a chemical that signals to the body to produce an inflammatory response. Interleukin production is accelerated by UV radiation.
Palmitoyl Tetrapeptide-7 tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tetrapeptide-7This synthetic peptide is created from lysine, valine, and palmitic acid.
According to the manufacturer, in-vitro studies show tissue growth and collagen synthesis. Another in-vivo study found 60 volunteers saw a significant reduction in wrinkles after 84 days.
Due to its palmitic acid base, this peptide may not be fungal-acne safe.
Learn more about Palmitoyl Tripeptide-5Niacinamide has emerged as an all-star ingredient due to its many benefits.
It is known to treat acne by reducing inflammation. It also helps fade dark-spots and strengthen the skin by promoting the growth of the ceramide barrier.
Other benefits include smoothing wrinkles and minimizing redness.
The cherry on top? Niacinamide can also help build keratin, a protein that keeps skin firm.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
Niacinamide can be mixed with other ingredients to boost benefits. For instance, it has shown to be effective when used with copper, folic acid, and zinc to treat acne.
Learn more about NiacinamideEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Ingredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
DRMTLGY Needle-Less Serum 29 ingredients
Le Mieux TGF-B Booster 32 ingredients
Reviews
Here's what our community thinks
DRMTLGY Needle-Less Serum 29 ingredients
The scent feels a bit artificial, and I’m not sure about its wrinkle-improving effects. However, it absorbs quickly and feels fresh without any stickiness. It helps smooth out skin texture well, but the hydration level is on the lower side.
Le Mieux TGF-B Booster 32 ingredients
On my wish list. According to my research, it seems to have quality growth factor ingredients, hydrating ingredients, and few of any ingredients I’m looking to avoid.
Edit: Finally splurged, and it is worth every penny. I can’t believe how great my skin looks and feels after just a few days. I’m trying using it every other day to make it more affordable. Will let you know how that goes. Show more
I do feel like I’m glowing and more hydrated.
I feel more refreshed under my eyes
And I like to think it’s keeping wrinkles at bay and doing its anti aging thing.
Super acne prone skin, and no issues.
It’s acne safe non comeogenic and no fatty alc and no tocopheryl. 💁🏼♀️
UPDATE; it isn’t fungal acne safe I’m currently using two products that aren’t safe and I think it may be this Show more
