Avène Cicalfate+ Restorative Protective Cream Versus Desitin Daily Defense Diaper Rash Cream
Updated on March 13, 2025
Overview
Suited For
They're both likely to be good for fighting acne, dry skin, brightening skin and scar healing
Free From
They both do not contain any harsh alcohols, common allergens, fragrances or parabens
What's Inside
They both contain oils and sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Avène Cicalfate+ Restorative Protective Cream 18 ingredients
Desitin Daily Defense Diaper Rash Cream 18 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
Avène Cicalfate+ Restorative Protective Cream 18 ingredients
Desitin Daily Defense Diaper Rash Cream 18 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningCaprylic/Capric Triglyceride
Masking
Paraffinum Liquidum
Emollient
Glycerin
Humectant
Hydrogenated Vegetable Oil
Emollient
Zinc Oxide
Cosmetic Colorant
Propylene Glycol
Humectant
Polyglyceryl-2 Sesquiisostearate
Emulsifying
PEG-22/Dodecyl Glycol Copolymer
EmulsifyingAluminum Stearate
Cosmetic ColorantAquaphilus Dolomiae Ferment Filtrate
Skin ConditioningArginine
Masking
Beeswax
Emulsion Stabilising
Copper Sulfate
Skin Conditioning
Magnesium Stearate
Cosmetic ColorantMicrocrystalline Wax
Emulsion Stabilising
Tromethamine
BufferingZinc Sulfate
Antimicrobial
Water, Caprylic/Capric Triglyceride, Paraffinum Liquidum, Glycerin, Hydrogenated Vegetable Oil, Zinc Oxide, Propylene Glycol, Polyglyceryl-2 Sesquiisostearate, PEG-22/Dodecyl Glycol Copolymer, Aluminum Stearate, Aquaphilus Dolomiae Ferment Filtrate, Arginine, Beeswax, Copper Sulfate, Magnesium Stearate, Microcrystalline Wax, Tromethamine, Zinc Sulfate
Zinc Oxide 13%
Cosmetic Colorant
Water
Skin ConditioningParaffinum Liquidum
Emollient
Petrolatum
Emollient
Beeswax
Emulsion Stabilising
Dimethicone
Emollient
Sorbitan Sesquioleate
Emulsifying
Microcrystalline Wax
Emulsion Stabilising
PEG-30 Dipolyhydroxystearate
Emulsifying
Aloe Barbadensis Leaf Extract
Emollient
Glycerin
Humectant
Tropolone
Skin ConditioningTocopheryl Acetate
Antioxidant
1,2-Hexanediol
Skin Conditioning
Caprylyl Glycol
EmollientMagnesium Sulfate
Potassium Hydroxide
BufferingPhenoxyethanol
Preservative
Zinc Oxide 13%, Water, Paraffinum Liquidum, Petrolatum, Beeswax, Dimethicone, Sorbitan Sesquioleate, Microcrystalline Wax, PEG-30 Dipolyhydroxystearate, Aloe Barbadensis Leaf Extract, Glycerin, Tropolone, Tocopheryl Acetate, 1,2-Hexanediol, Caprylyl Glycol, Magnesium Sulfate, Potassium Hydroxide, Phenoxyethanol
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Beeswax is natural wax produced by honey bees and can be synthetically created. It consists mainly of fatty acid esters and long-chain alcohols.
In cosmetics, beeswax is a emollient. Due to its waxy structure, it creates a protective barrier. This barrier prevents water from evaporating off the skin.
This may not be a good ingredient for oily skin. We recommend speaking with a professional if you have concerns.
Beeswax cannot be removed with water, but can be taken off with an oil cleanser.
Beeswax is also antiseptic and contains vitamin A.
Learn more about BeeswaxGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinMicrocrystalline Wax is created by de-oiling petroleum. It is highly refined and purified before being added to cosmetics.
Microcrystalline Wax is used to enhance the texture and create even consistency. It helps stabilize a product by preventing ingredients from separating.
Paraffinum Liquidum is also known as liquid paraffin. It is a type of highly refined mineral oil.
Like other oils, Paraffinum Liquidum has emollient properties. Emollients help soothe and soften the skin. By creating a barrier to trap moisture within, emollients help keep your skin hydrated.
Paraffinum Liquidum does not irritate the skin and is non-comedogenic.
Learn more about Paraffinum LiquidumWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterZinc Oxide is a mineral broad-spectrum UV filter; it is the broadest UVA and UVB reflector approved by the FDA. While it is most commonly man-made for cosmetics, it can naturally occur in zincite, a rare mineral.
Today, traditional and nano-sized zinc oxide can be found in beauty products. Nano-sized zinc oxide can enhance a product's UV protection. While it is not believed to have a negative effect on skin, nano-zinc oxide may be harmful to coral reefs - though the verdict is not entirely out on this one.
Zinc Oxide also has antibacterial and calming properties. It is not water soluble.
Zinc has been used throughout history as an ingredient in paint and medicine. An Indian text from 500BC is believed to list zinc oxide as a salve for open wound. The Ancient Greek physician Dioscorides has also mentioned the use of zinc as an ointment in 1AD.
Learn more about Zinc OxideIngredient Ratings
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When to use
Avène Cicalfate+ Restorative Protective Cream 18 ingredients
Desitin Daily Defense Diaper Rash Cream 18 ingredients
Reviews
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