Overview
What it is
Serum with 22 ingredients that contains AHA, niacinamide and retinoid
Cool Features
It is reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any common allergens, parabens, silicones or sulfates
Fun facts
SANA is from Japan.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside (and what isn't)
Ingredients List
Dive into the full list of ingredients.
Niacinamide
SmoothingWater
Skin ConditioningGlycerin
HumectantButylene Glycol
HumectantAlcohol Denat.
AntimicrobialEthyl Ethylhexanoate
PerfumingMilk Ferment
Skin ConditioningRetinol
Skin ConditioningLactic Acid
BufferingN-Stearoyl-Dihydrosphingosine
Skin ConditioningCyclodextrin
AbsorbentArginine
MaskingPolyvinylalcohol Crosspolymer
Cellulose Gum
Emulsion StabilisingLinum Usitatissimum Seed Polysaccharide
Glycine Soja Extract
Skin ConditioningIsostearyl Isostearate
EmollientPhytosterols
Skin ConditioningHydrogenated Castor Oil
EmollientPotassium Hydroxide
BufferingHydrogenated Phosphatidylcholine
EmulsifyingPhenoxyethanol
PreservativeNiacinamide, Water, Glycerin, Butylene Glycol, Alcohol Denat., Ethyl Ethylhexanoate, Milk Ferment, Retinol, Lactic Acid, N-Stearoyl-Dihydrosphingosine, Cyclodextrin, Arginine, Polyvinylalcohol Crosspolymer, Cellulose Gum, Linum Usitatissimum Seed Polysaccharide, Glycine Soja Extract, Isostearyl Isostearate, Phytosterols, Hydrogenated Castor Oil, Potassium Hydroxide, Hydrogenated Phosphatidylcholine, Phenoxyethanol
Key Ingredients
Benefits
Concerns
Ingredients Explained
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolAlcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.
This ingredient gets a bad rep because it is irritating and drying - mostly due to its astringent property. Astringents draw out natural oils in tissue, constricting pores and leaving your skin dried out.
However, alcohol denat. is not all that bad.
Due to its low molecular weight, alcohol denat. tends to evaporate quickly. One study on pig skin found half of applied alcohol evaporated in 10 seconds and less than 3% stayed on skin.
This also helps other ingredients become better absorbed upon application.
Studies are conflicted about whether this ingredient causes skin dehydration. One study from 2005 found adding emollients to propanol-based sanitizer decreased skin dryness and irritation. Another study found irritation only occurs if your skin is already damaged.
Small amounts of alcohol are generally tolerated by oily skin or people who live in humid environments.
The rule of thumb is if this alcohol is near the end of an ingredients list, it will probably not affect your skin much.
Also...
This ingredient has antimicrobial and solvent properties.
The antimicrobial property helps preserve products and increase their shelf life. As a solvent, it helps dissolve other ingredients.
Other types of astringent alcohols include:
Learn more about Alcohol Denat.Ethyl Ethylhexanoate is a fragrance.
We don't have a description for Milk Ferment yet.
Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
Why is retinol famous?
It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.
Retinol is proven to:
This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.
Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).
Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.
We recommend speaking with a medical professional about using this ingredient during pregnancy.
Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.
Read about Tretinoin
Learn more about RetinolLactic Acid is an AHA that is derived from fermenting lactose, a carbohydrate from milk. It removes the top layer of old and dead skin cells and helps increase cell turnover.
Benefits of Lactic Acid are that it can help to reduce large pores and reduce the effects of aging. Some potential downsides are that it can be bad for dry skin, cause irritation, worsen eczema, and worsen rosacea.
Not only does it help exfoliate the skin, it helps strengthen the skin's barrier. When applied, lactic acid helps the skin create ceramides.
Lactic acid is an over-the-counter chemical exfoliant that comes from the fermentation of lactose — a carbohydrate found in milk.
Legend has it that Cleopatra used to bathe in sour milk to help reduce wrinkles.
Read more about some other popular AHA's here:
Learn more about Lactic AcidWe don't have a description for N-Stearoyl-Dihydrosphingosine yet.
We don't have a description for Cyclodextrin yet.
Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.
As a cosmetic ingredient, Arginine has antioxidant properties and can also help repair damaged skin. This ingredient is derived either synthetically or from animals.
Arginine isn't fungal acne safe when used in the presence of other lipids (fats, fatty acids, oils, esters, etc). Oils and fats occur naturally within the skin, so take caution when using Arginine if you're prone to fungal acne.
Learn more about ArginineWe don't have a description for Polyvinylalcohol Crosspolymer yet.
Cellulose Gum is a water-soluble polymer that comes from cellulose. It is used to change the texture of a product and to help stabilize emulsions.
As an emulsifier, cellulose gum specifically thicken the texture of water-based products.
This ingredient is considered hypoallergenic and non-toxic. Cellulose Gum can be found in cosmetics, food, and other household goods such as paper products.
Learn more about Cellulose GumWe don't have a description for Linum Usitatissimum Seed Polysaccharide yet.
Glycine Soja Extract comes from the soybean. Glycine Soja is native to eastern Asia.
Soybeans are rich in antioxidants. Antioxidants may improve the signs of aging.
Studies show soy may help fade hyperpigmentation from UVB. It does so by disrupting the melanin process from UVB induced skin inflammation.
Soybeans are rich in proteins and are part of the legume family. Foods made with soybeans include tofu, soymilk, edamame, miso, and soy sauce.
Learn more about Glycine Soja ExtractIsostearyl Isostearate comes from Isostearyl Alcohol and Isostearic Acid. It is usually derived from vegetables, such as canola oil.
Isostearyl Isostearate is an emollient and helps soften skin. It can also help thicken a product.
This ingredient isn't fungal acne safe. It can be bad for oily skin.
Learn more about Isostearyl IsostearatePhytosterols come from plants, nuts, and whole grains. These compounds have skin soothing and moisturizing properties.
Fun fact: They are similar to cholesterol and can help lower cholesterol levels.
Hydrogenated Castor Oil is created by adding hydrogen to castor oil. This helps stabilize the castor oil and raises the melting point. At room temperature, hydrogenated castor oil is solid.
Castor Oil helps moisturize the skin. It is rich in a fatty acid called ricinoleic acid. This fatty acid helps prevent moisture loss on the skin. This helps keep your skin soft and hydrated. Ricinoleic acid also has anti-inflammatory and pain reducing properties.
As a wax-like substance, Hydrogenated Castor Oil acts as an emollient. Emollients help keep your skin stay soft and smooth by creating a barrier. This barrier helps trap moisture.
Hydrogenated Castor Oil may not be fungal-acne safe. We recommend speaking with a professional.
Learn more about Hydrogenated Castor OilPotassium hydroxide is commonly known as caustic potash. It is used to fix the pH of a product or as a cleaning agent in soap. In cleansers, it is used for the saponification of oils.
Sapnification is the process of creating fatty acid metal salts from triglycerides and a strong base. During this process, Potassium Hydroxide is used up and is not present in the final product.
Using high concentrations of Potassium Hydroxide have shown to irritate the skin.
Learn more about Potassium HydroxideWe don't have a description for Hydrogenated Phosphatidylcholine yet.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
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Where it's from
SANA is a Japanese brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Published May 9, 2025 • Added by MonicaDoan