Bioage Skincare Bio.PDRN E Gaba Intensive
A serum with 16 ingredients, including hyaluronic acid and peptides.
Overview
What it is
Serum with 16 ingredients that contains hyaluronic acid and peptides
Cool Features
It is vegan, cruelty-free, fungal acne (malassezia) safe, and reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, sensitive skin and scar healing
Free From
It doesn't contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates
Fun facts
Bioage Skincare is from Brazil.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPanthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolPropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.Â
Itâs often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about Propanediol1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.Â
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesÂ
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumAminobutyric Acid is an antioxidant. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.
Studies have shown Gamma-Aminobutyric Acid may reduce hyperpigmentation.
Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of âFRAGRANCEâ or âPARFUMâ according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumCitric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidAminomethyl Propanol is used to adjust the pH of products. It is also used as a base to create other organic compounds. Having a balanced pH is important for protecting your skin.
Aminomethyl propanol is safe to use in cosmetics up to 1%. It is soluble in water.
Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTACaprylhydroxamic Acid is a chelating agent that helps cosmetics stay fresh, stable, and consistent over time.
Chelating agents help prevent metal ions from binding to other ingredients. This helps prevent unwanted reactions and effects from using the product. It also helps prevent the growth of unwanted microbes in products that contain water.
Caprylhydroxamic Acid is often used with natural antimicrobial products as an alternative to preservatives.
Learn more about Caprylhydroxamic AcidSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateSodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoateSodium DNA is an emerging anti-aging ingredient.
It is created by taking deoxyribonucleic acid (DNA) and purifying it with sodium hydroxide.
The DNA is extracted from several different animal sources, including: calf thymus, the gonadic tissue of a male sturgeon, or herring / salmon sperm.
You have probably seen this ingredient in anti-aging skincare. But what is it?
DNA is composed of nucleotides, or chemical building blocks. Nucleotides include adenine (A), thymine (T), guanine (G), and cytosine (C). Talk about a flashback to biology! Nucleosides are formed from these nucleotides.
The science behind Sodium DNA is based on an ingredient called Polydeoxyribonucleotide or PDRN.
PDRN are DNA fragments mainly extracted from the sperm cells of trout or salmon. Meaning, PDRN can be derived from Sodium DNA.
PDRN consists of chains of nucleotides and nucleosides mentioned above. They can range anywhere from 80 - 2000 pairs.
Studies show PDRN has the following properties:
Most of the research on PDRN has been done using injectable forms. Thatâs important, because PDRN is a large molecule and doesnât absorb well through the skin. So if youâre applying it topically, the effects are likely to be much milder.
Still, topical Sodium DNA is emerging as a trendy anti-aging ingredient. Itâs generally well-tolerated and offers good biocompatibility with human skin, making it a low-risk addition to most routines.
Further studies are needed to truly confirm this ingredients anti-aging ability (Remember, retinol has decades of research!).
Sodium DNA may be sourced from fish, animal tissue, or plants. Since this isnât always disclosed, we recommend asking the brand directly if the ingredientâs origin is important to you.
Learn more about Sodium DnaAcetyl Hexapeptide-8, commonly known as Argireline or Acetyl Hexapeptide-3, is a popular peptide in skincare. Itâs often referred to as a âBotox-likeâ ingredient because it helps reduce muscle movement.
By relaxing these micro-movements, Argireline may help minimize the appearance of fine lines and wrinkles. That said, itâs not as powerful as Botox, and research on its long-term effectiveness is still limited.
Beyond smoothing, Argireline may also support collagen production. Collagen is the protein that helps keep your skin firm, bouncy, and well-hydrated by strengthening the skin barrier.
So while Argireline isnât a miracle fix, it can be a helpful addition to a routine focused on both prevention and skin health.
Read more about other common types of peptides here:
Learn more about Acetyl Hexapeptide-8Reviews
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Where it's from
Bioage Skincare is a Brazilian brand
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The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated October 26, 2025 • Added by wthtay