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Updated on October 22, 2023

Overview

What they are

These products are both prescription. They have a total of 3 ingredients in common

Cool Features

They both contain retinoid

Suited For

They're both likely to be good for fighting acne, anti aging and brightening skin

Free From

They both do not contain any oils, silicones or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Obagi Tretinoin 0.05% Gel
Obagi Tretinoin 0.05% Gel
Prescription
American Brand United States
Obagi Tretinoin Cream 0.1%
Obagi Tretinoin Cream 0.1%
Prescription
American Brand United States

Ingredient Info

Click any item below to learn more and see relevant ingredients

Obagi Tretinoin 0.05% Gel 16 ingredients

Obagi Tretinoin Cream 0.1% 9 ingredients

At a glance

Click on any of the items below to learn more

Obagi Tretinoin 0.05% Gel 16 ingredients

Obagi Tretinoin Cream 0.1% 9 ingredients

Notable Ingredients

Benefits

Concerns

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Tretinoin 0.05% Gel
Tretinoin
Retinoid IconHelps with Anti-Aging IconHelps fight Acne IconHelps brighten skin IconMay cause irritation IconMay worsen Rosacea Icon
RetinoidRetinoid Icon 3 Benefits 2 Concerns

Tretinoin is the best retinoid due to its proven skin benefits. It only available with a prescription in many countries.

Benzyl Alcohol Perfuming, Preservative, Solvent
Alcohol IconFragrance IconPreservative IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon
AlcoholAlcohol Icon FragranceFragrance Icon PreservativePreservative Icon 6 Concerns

Benzyl Alcohol is most commonly used as a preservative. It also has a subtle, sweet smell. Small amounts of Benzyl Alcohol is not irritating and safe to use in skincare products. Most Benzyl Alcohol is derived from fruits such as apricots.

Very Disliked Full details ->
Butylparaben Masking, Preservative
Preservative IconParaben IconCan worsen Dry Skin IconNon-Reef-Safe IconMay worsen Eczema Icon
PreservativePreservative Icon ParabenParaben Icon 3 Concerns

Butylparaben is a preservative, is a paraben, and is not reef safe. It can be bad for dry skin and worsen eczema.

Very Disliked Full details ->
BHT Antioxidant, Masking
Antioxidant Icon
AntioxidantAntioxidant Icon

BHT is a synthetic antioxidant. As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.

Very Disliked Full details ->
Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Ethylparaben Preservative
Preservative IconParaben IconNon-Reef-Safe Icon
PreservativePreservative Icon ParabenParaben Icon Non-Reef-SafeNon-Reef-Safe Icon

Ethylparaben is a preservative, is a paraben, and is not reef safe.

Very Disliked Full details ->
Hydrolyzed Collagen Emollient, Humectant, Skin Conditioning
Helps with Anti-Aging Icon
Helps with Anti-AgingHelps with Anti-Aging Icon

Hydrolyzed collagen has a misleading name because it is actually a mixture of various proteins/peptides. This ingredient has skin hydrating properties.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Isobutylparaben Antimicrobial
Paraben IconCan worsen Dry Skin Icon
ParabenParaben Icon Can worsen Dry SkinCan worsen Dry Skin Icon

Isobutylparaben is a paraben. It can be bad for dry skin.

Very Disliked Full details ->
Methylparaben Preservative
0 / 0 Preservative IconParaben IconNon-Reef-Safe IconMay worsen Eczema Icon
PreservativePreservative Icon ParabenParaben Icon 2 Concerns

Methylparaben is a preservative and is a paraben. It is used to prevent the growth of fungus, mold, and other harmful bacteria. Parabens are chemicals used as preservatives in both cosmetics and food.

0 Com. / 0 Irr.
Very Disliked Full details ->
Octoxynol-9 Emulsifying
0-1 / 0

Octoxynol-9 are part of a group called ethoxylated alkyl phenols. Octoxynols are usually found in hair-coloring products.

0-1 Com. / 0 Irr.
Unknown Full details ->
Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
Propylparaben Preservative
0 / 0 Preservative IconParaben IconCan worsen Dry Skin IconNon-Reef-Safe Icon
PreservativePreservative Icon ParabenParaben Icon 2 Concerns

Propylparaben is a preservative and is a paraben with antifungal and antimicrobial properties.

0 Com. / 0 Irr.
Very Disliked Full details ->
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Triethanolamine Buffering, Emulsifying, Masking
2 / 0

Triethanolamine is an emulsifier and pH adjuster. It is created using ethylene oxide and ammonia. This gives Triethanolamine a nitrogen core and a similar scent to ammonia.

2 Com. / 0 Irr.
Very Disliked Full details ->
Tretinoin Cream 0.1%
Tretinoin
Retinoid IconHelps with Anti-Aging IconHelps fight Acne IconHelps brighten skin IconMay cause irritation IconMay worsen Rosacea Icon
RetinoidRetinoid Icon 3 Benefits 2 Concerns

Tretinoin is the best retinoid due to its proven skin benefits. It only available with a prescription in many countries.

Stearic Acid Cleansing, Emulsifying, Emulsion Stabilising
2-3 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon
2 Concerns

Stearic Acid is a fatty acid. It is an emollient, emulsifier, and texture enhancer.

2-3 Com. / 0 Irr.
Very Disliked Full details ->
Isopropyl Myristate Emollient, Masking
3-5 / 3 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon
3 Concerns

Isopropyl Myristate is an emollient, thickening agent, and texture enhancer. It is created from isopropyl alcohol and myristic acid.

3-5 Com. / 3 Irr.
Very Disliked Full details ->
Peg-8 Stearate Emulsifying, Humectant
3 / 1 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Peg-8 Stearate is an emulsifier and humectant.

3 Com. / 1 Irr.
Unknown Full details ->
Stearyl Alcohol Emollient, Emulsifying, Emulsion Stabilising
2 / 2 Fatty Alcohol Icon
Fatty AlcoholFatty Alcohol Icon

Stearyl Alcohol is a type of fatty alcohol from stearic acid. It is a white, waxy compound used to emulsify ingredients.

2 Com. / 2 Irr.
Very Disliked Full details ->
Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Sorbic Acid Preservative
Preservative IconMay worsen Eczema Icon
PreservativePreservative Icon May worsen EczemaMay worsen Eczema Icon

Sorbic Acid is a preservative. It is the most commonly used food preservative in the world.

Very Disliked Full details ->
BHT Antioxidant, Masking
Antioxidant Icon
AntioxidantAntioxidant Icon

BHT is a synthetic antioxidant. As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.

Very Disliked Full details ->
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Loved

Tretinoin is the best retinoid due to its proven skin benefits. It only available with a prescription in many countries.

All forms of OTC retinoids goes through a conversion line until it can become effective. The final step of conversion is retinoic acid; retinoic acid IS Tretinoin.

This is why tretinoin is so effective; it gets to work immediately on the skin.

Research on tretinoin has found it to be incredibly effective for reducing the signs of aging. It helps improve damage from the sun, even the skin tone, and smooth out wrinkles. It is also an effective acne treatment by reducing and balancing out sebum production in pores.

Tretinoin, like other forms of Vitamin A, increases the turnover cycle of skin cells. This helps the skin create newer and healthier skin cells faster.

It can cause irritation, redness, and dry skin because it is considered a "strong" ingredient. Those with sensitive skin should consult a professional about using tretinoin.

Using retinoids will increase sun-sensitivity in the first few weeks of use. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

Read about a form of retinoid you can purchase at the store, retinol.

Learn more about Tretinoin
BHT
Antioxidant, Masking
Very Disliked

BHT is a synthetic antioxidant. As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.

BHT also helps stabilize products and prevent them from degrading. Many products are sensitive to air and light. BHT prevents them from breaking down when exposed.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

Ingredient Ratings

Here's what our community thinks of the ingredients in these two products.

Tretinoin 0.05% Gel
5
10
1
liked
mixed
disliked
not rated
Tretinoin Cream 0.1%
2
6
1
liked
mixed
disliked
not rated

When to use

Obagi Tretinoin 0.05% Gel 16 ingredients

Obagi Tretinoin Cream 0.1% 9 ingredients

35 Routines
0% use in am
100% use in pm
86% use every day
When to use See routines that use it ->
41 Routines
7% use in am
93% use in pm
85% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Obagi Tretinoin 0.05% Gel 16 ingredients

Tretinoin 0.05% Gel hasn't been rated yet.
Rate it now

Obagi Tretinoin Cream 0.1% 9 ingredients

5.0 /5
from 1 rating
Tavus's avatar

Tavus

10 months ago · Combination Skin
Review

Tretinoin cream ACNELYSE 0.1% by Abdi Ibrahim. This Turkish pharmaceutical company produces a good quality tretinoin cream. Retinoic acid (vitamin...

Tretinoin cream ACNELYSE 0.1% by Abdi Ibrahim. This Turkish pharmaceutical company produces a good quality tretinoin cream. Retinoic acid (vitamin A in its most optimal form) is the single best ingredient to fight wrinkles.