Versus

Galderma TWYNEO cream Versus Differin 0.1% w/w Cream

Facial Treatment
Facial Treatment
Swiss Brand Switzerland
American Brand United States

Updated on September 04, 2024

Overview

What they are

These products are both facial treatments. They have a total of 7 ingredients in common

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing and better texture

Free From

They both do not contain any harsh alcohols, common allergens, fragrances, oils or sulfates

What's Inside

They both contain silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

Galderma TWYNEO cream 20 ingredients

Differin 0.1% w/w Cream 12 ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Galderma TWYNEO cream 20 ingredients

Differin 0.1% w/w Cream 12 ingredients

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Emulsion Stabilising, Gel Forming

Carbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

Emollient, Skin Conditioning, Solvent

Cyclomethicone is a class of silicones used to improve the texture of products.

Their cyclic or circular structure decreases stability. This causes quick evaporation when applied to skin. Cyclomethicones are often used as a carrier for other ingredients. Once it evaporates, it leaves a silky barrier on the skin.

The most popular types of cyclomethicones include D5 and D6.

Learn more about Cyclomethicone

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Learn more about Sodium Hydroxide
Emollient, Skin Conditioning

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan?

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Learn more about Squalane

When to use

Galderma TWYNEO cream 20 ingredients

Differin 0.1% w/w Cream 12 ingredients

2 Routines
0% use in am
100% use in pm
100% use every day
213 Routines
9% use in am
91% use in pm
81% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Galderma TWYNEO cream 20 ingredients

3.0 /5
from 1 rating
Drying (1) Irritating (1) No Scent (1)
Lelo's avatar

Lelo .

3 months ago
Review

I am currently battling some of the worse acne vulgaris of my life. I was prescribed this topical from my dermatologist and it has SIGNIFICANTLY helped my breakout. I saw a HUGE difference just within 24 hours after application. WARNING: it is extremely drying, I would recommend following your dermatologist instructions when using this. A little goes a long way! I used a pea sized amount for my Show more

#drying
#irritating
#no scent
#works well

Differin 0.1% w/w Cream 12 ingredients

3.7 /5
from 3 ratings
Absorbs Well (1) Great Value (1) Light (1)
oumoukadamzachrisson's avatar
Review

With consistency and patience differin is definitely a reliable and effective treatment for acne. I use this every evening and since I started (about 1,5 years ago I believe now) it has shown great results. I debated putting a 5 star rating but because it do take quite some time and has yet to completely get rid of my acne I put a 4.

𝘌𝘹𝘵𝘳𝘢:
I was previously prescribed with epiduo which ended Show more

#great value
#light
#absorbs well
#no scent