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Apostrophe Hydroquinone 6% Prescription Versus Perrigo Hydroquinone 4% Cream

Prescription
Facial Treatment
American Brand United States
American Brand United States

Overview

Suited For

They're both likely to be good for dark spots

Free From

They both do not contain any harsh alcohols, common allergens, silicones or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

Free from

Safety & Ethics

American Brand

Brand country of origin

Free from

Safety & Ethics

American Brand

Brand country of origin

At a glance

Click on any of the items below to learn more

Ingredients, at a glance

What's in this product, and how it might affect your skin.

Notable Ingredients

Benefits

Concerns

Ingredients, at a glance

What's in this product, and how it might affect your skin.

Benefits

Concerns

Ingredients Side-by-side

found in both products
Hydroquinone 6% Prescription
Hydroquinone 6% Stabilising
Good for Dark Spots IconMay worsen Rosacea Icon

Hydroquinone is used to treat hyperpigmentation, acne scars, and age spots.

Mixed reviews
Good for Dark SpotsGood for Dark Spots IconMay worsen RosaceaMay worsen Rosacea Icon
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Aloe Barbadensis Leaf Juice Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation Icon

Aloe Barbadensis Leaf Juice comes from leaves of the aloe plant. Aloe Barbadensis Leaf Juice is best known for helping to soothe sunburns. It is also anti-inflammatory, moisturizing, antiseptic, and can help heal wounds.

Liked by users
2 Benefits
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C13-14 Isoparaffin Emollient, Solvent
May worsen Oily Skin IconNot safe for Fungal Acne Icon

C13-14 Isoparaffin is created from petroleum-based mineral oils. It is an emollient and helps thicken a product.

Very disliked
2 Concerns
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Caprylic/Capric Triglyceride Masking, Skin Conditioning

Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

Mixed reviews
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Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Loved by users
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Laureth-7 Emulsifying

Laureth-7 is created by the ethoxylation of lauryl alcohol using ethylene oxide. Lauryl alcohol is a fatty alcohol with hydrating properties.

Very disliked
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Phenoxyethanol Preservative
Preservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very disliked
PreservativePreservative Icon
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Polyacrylamide

Polyacrylamide is a synthetic polymer. It is used to stabilize products and bind ingredients. When hydrated, Polyacrylamide forms a soft gel.

Disliked by users
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Tocopheryl Acetate Antioxidant, Skin Conditioning
0 / 0 Vitamin E IconAntioxidant Icon

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

0 Com. / 0 Irr.
Liked by users
Vitamin EVitamin E IconAntioxidantAntioxidant Icon
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Triethylene Glycol Masking, Perfuming
Fragrance Icon

Triethylene Glycol is a fragrance.

Not enough ratings
FragranceFragrance Icon
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Hydroquinone 4% Cream
Hydroquinone 4% Stabilising
Good for Dark Spots IconMay worsen Rosacea Icon

Hydroquinone is used to treat hyperpigmentation, acne scars, and age spots.

Mixed reviews
Good for Dark SpotsGood for Dark Spots IconMay worsen RosaceaMay worsen Rosacea Icon
Learn more
Glyceryl Stearate Emollient, Emulsifying
1 / 0 Not safe for Fungal Acne Icon

Glyceryl Stearate is a mix of glycerin and stearic acid.

1 Com. / 0 Irr.
Disliked by users
Not safe for Fungal AcneNot safe for Fungal Acne Icon
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Paraffinum Liquidum Emollient, Skin Protecting, Solvent
0-2 / 0 Oil IconMay worsen Oily Skin IconNot safe for Fungal Acne Icon

Paraffinum Liquidum is also known as liquid paraffin. It is a type of highly refined mineral oil.

0-2 Com. / 0 Irr.
Disliked by users
OilOil Icon2 Concerns
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PEG-40 Stearate Emulsifying
Not safe for Fungal Acne Icon

Peg-40 Stearate is a waxy solid made up of polyethylene glycol and stearic acid. It is an emulsifier and cleanser. Emulsifiers help oils and water mix.

Very disliked
Not safe for Fungal AcneNot safe for Fungal Acne Icon
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Propylene Glycol Humectant, Skin Conditioning, Solvent
0 / 0 Helps hydrate Dry Skin IconMay worsen Eczema IconMay worsen Rosacea Icon

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

0 Com. / 0 Irr.
Very disliked
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon2 Concerns
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Propylparaben Preservative
0 / 0 Preservative IconParaben IconCan worsen Dry Skin IconNon-Reef-Safe Icon

Propylparaben is a preservative and is a paraben with antifungal and antimicrobial properties.

0 Com. / 0 Irr.
Very disliked
PreservativePreservative IconParabenParaben Icon2 Concerns
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Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Loved by users
Learn more
Sodium Metabisulfite Antioxidant, Preservative
Antioxidant IconPreservative Icon

Sodium Metabisulfite is an antioxidant and is a preservative.

Mixed reviews
AntioxidantAntioxidant IconPreservativePreservative Icon
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Squalane Emollient, Skin Conditioning
1 / 0 Helps hydrate Dry Skin Icon

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

1 Com. / 0 Irr.
Loved by users
Helps hydrate Dry SkinHelps hydrate Dry Skin Icon
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Stearic Acid Cleansing, Emulsifying, Emulsion Stabilising
2-3 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Stearic Acid is a fatty acid. It is an emollient, emulsifier, and texture enhancer.

2-3 Com. / 0 Irr.
Very disliked
2 Concerns
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PEG-25 Propylene Glycol Stearate Emulsifying

We don't have a description for PEG-25 Propylene Glycol Stearate yet.

Not enough ratings
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Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Stabilising
Mixed

Hydroquinone is used to treat hyperpigmentation, acne scars, and age spots.

It works by decreasing the melanocytes in your skin. Melanocytes are cells that create melanin (the color pigment in skin).

Be sure to use this ingredient as prescribed by your doctor. Wearing sunscreen is also a must (you should be wearing sunscreen anyway!).

Most hydroquinone prescriptions are not to be used for longer than 3 months. Long term usage can cause ochronosis, or a condition in which the skin darkens more than before.

This ingredient is banned in the EU for being skin sensitizer. In the US, this ingredient is not allowed for over-the-counter sale.

However, it is still possible to get hydroquinone in the EU, US, Canada, Australia, and Japan from a doctor's prescription.

There is no known research backing this ingredient to be carcinogenic in humans.

Check out the European alternative to hydroquinone here.

Gentle reminder that all skin tones are beautiful!

Learn more about Hydroquinone
Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

32 Routines
28% use in am
72% use in pm
88% use every day
When to use See routines that use it ->
59 Routines
29% use in am
71% use in pm
86% use every day
When to use See routines that use it ->