Le Mieux EGF-DNA Serum
A serum with 31 ingredients, including hyaluronic acid and peptides.
Overview
What it is
Serum with 31 ingredients that contains hyaluronic acid and peptides
Cool Features
It is vegan, cruelty-free, and reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, brightening skin, sensitive skin, scar healing and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates
Fun facts
Le Mieux is from .
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside (and what isn't)
Ingredients List
Dive into the full list of ingredients.
Galactomyces Ferment Filtrate
HumectantSodium Hyaluronate
HumectantOryza Sativa Bran Water
MaskingHyaluronic Acid
HumectantZinc Hydrolyzed Hyaluronate
HumectantHydroxypropyltrimonium Hyaluronate
Sodium Hyaluronate Dimethylsilanol
HumectantSodium Hyaluronate Crosspolymer
HumectantC12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate
Hydrolyzed Hyaluronic Acid
HumectantSodium Acetylated Hyaluronate
HumectantAscorbyl Propyl Hyaluronate
Skin ConditioningOligopeptide-22
Skin ConditioningOligopeptide-25
Skin ConditioningSh-Oligopeptide-1
Skin ConditioningSh-Oligopeptide-2
Skin ConditioningSaccharomyces Ferment Filtrate
HumectantPhospholipids
Skin ConditioningSaccharomyces Lysate Extract
HumectantLecithin
EmollientAcetyl Glutamine
Skin ConditioningPropanediol
SolventBacillus/Folic Acid Ferment Filtrate Extract
AntioxidantSh-Polypeptide-1
Skin ConditioningSh-Polypeptide-9
Skin ConditioningSh-Polypeptide-11
Hydroxyethylcellulose
Emulsion StabilisingXanthan Gum
EmulsifyingPentylene Glycol
Skin ConditioningCaprylyl Glycol
EmollientEthylhexylglycerin
Skin ConditioningGalactomyces Ferment Filtrate, Sodium Hyaluronate, Oryza Sativa Bran Water, Hyaluronic Acid, Zinc Hydrolyzed Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Dimethylsilanol, Sodium Hyaluronate Crosspolymer, C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Ascorbyl Propyl Hyaluronate, Oligopeptide-22, Oligopeptide-25, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Saccharomyces Ferment Filtrate, Phospholipids, Saccharomyces Lysate Extract, Lecithin, Acetyl Glutamine, Propanediol, Bacillus/Folic Acid Ferment Filtrate Extract, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Hydroxyethylcellulose, Xanthan Gum, Pentylene Glycol, Caprylyl Glycol, Ethylhexylglycerin
Key Ingredients
Benefits
Ingredients Explained
Galactomyces Ferment Filtrate (GFF) is a yeast traditionally used to make the Japanese alcoholic beverage, sake.
GFF has moisturizing and antioxidant properties.
Studies show GFF improves our skin's natural moisturizing factors (NMF). Our NMF consists of many components that naturally moisturize our skin. Having healthy NMF keeps our skin plump, protected, and hydrated.
This ingredient tells our skin to create more filaggrin, an important component for NMF.
Filaggrin gathers all the structural proteins in our outer layer of skin and creates a tight barrier, helping to protect our skin against allergens and bacteria. This also helps prevent moisture loss.
Thanks to its antioxidant properties, GFF also protects our skin against oxidative stress and UV induced inflammation.
One study found GFF helped regulate sebum (oil) production and keratin in participants.
GFF may not be fungal-acne safe. We recommend speaking with a professional if you have concerns.
Many components of sake, such as GFF, are studied for their anti-aging benefits today. This is because sake brewers are known to have youthful hands.
Learn more about Galactomyces Ferment FiltrateSodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateOryza Sativa Bran Water comes from the outer layer of a rice kernel. It is a byproduct of milling rice, or the operation to produce a whole grain rice product.
According to INCI, this ingredient is used for masking and perfuming.
Masking ingredients are used to obscure or block properties of other ingredients. They are commonly used to block the scent of a product.
Peruming ingredients help give products a scent and can be natural or synthetically created.
Learn more about Oryza Sativa Bran WaterHyaluronic acid is naturally found in healthy skin. It is a humectant, meaning it draws moisture to your skin.
This ingredient helps hydrate, soothe, and protect the skin.
What makes hyaluronic acid so hydrating? It has the capacity to bind or hold large amounts of water.
Fun fact: It is already naturally found in our bodies, such as the fluids of our eyes and our joints.
Studies find this ingredient to have anti-inflammatory and anti-microbial properties. This can help speed up wound-healing.
Hyaluronic acid can be irritating if the molecule has a low-molecular weight, or if the molecules are small.
One study found low-molecular weight hyaluronic acid to be pro-inflammatory, meaning some people may experience irritation. This is because our bodies use hyaluronic acid in the wound-healing process to signal to our bodies, via irritation, that something needs healing.
The same study found high-molecular weight hyaluronic acid to be anti-inflammatory.
These are some other common types of Hyaluronic Acid:
Learn more about Hyaluronic AcidWe don't have a description for Zinc Hydrolyzed Hyaluronate yet.
This form of hyaluronic acid is produced through fermentation.
According to a manufacturer, it has a positive charge by ionic binding to help moisturize and give hair a smooth feel. This is why you'll find this ingredient in shampoos and body washes.
We don't have a description for Sodium Hyaluronate Dimethylsilanol yet.
Sodium Hyaluronate Crosspolymer is a type of hyaluronic acid. In fact, it is modified version of hyaluronic acid.
The structure of Sodium Hyaluronate Crosspolymer allows it to stay in the skin's top layer for a longer period of time. This allows for even more hydration and humectant action than hyaluronic acid.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium Hyaluronate CrosspolymerWe don't have a description for C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate yet.
Hydrolyzed Hyaluronic Acid is a form of hyaluronic acid. It is created by the hydrolysis of hyaluronic acid with a high molecular weight. Once created, Hydrolyzed Hyaluronic Acid has a low molecular weight.
Low molecular weight HA has been shown to hydrate and increase elasticity of the skin. Increasing elasticity is also associated with reduction of wrinkle depth.
One study found topical low molecular weight hyaluronic acid may be considered for the treatment of rosacea in the adult population. However, we always recommend speaking with a professional about your skin concerns.
Hyaluronic acids are a humectant. This means they draw moisture from the air. Hyaluronic acids help moisturize, soothe, and protect the skin.
Read more about other common forms of hyaluronic acid:
Learn more about Hydrolyzed Hyaluronic AcidSodium Acetylated Hyaluronate is a type of Hyaluronic Acid.
Hyaluronic Acids help moisturize, soothe, and protect the skin.
Read about common types of Hyaluronic Acid here:
Sodium Hyaluronate
Hydrolyzed Hyaluronic Acid
Hyaluronic Acid
Ascorbyl Propyl Hyaluronate can help to reduce redness, improve skin texture, reduce the effects of aging, and brighten skin.
Oligopeptide-22 is a peptide.
Oligopeptide-25 is a peptide.
sh-Oligopeptide-1 is a peptide found naturally in our bodies. Peptides are the building blocks for collagen and elastin in our skin.
In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.
Studies find EGF help with:
In South Korea and China, EGF is considered a controversial ingredient. The South Korean Ministry of Food and Drug Safety has cracked down on companies with products including EGF due to false advertisement claims.
According to Dr. Zoe Draelos, growth factors have some drawbacks:
There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.
Learn more about Sh-Oligopeptide-1This peptide has similar properties to Sh-Oligopeptide-1.
In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.
There is also controversy surrounding EGF. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.
Learn more about Sh-Oligopeptide-2Saccharomyces Ferment Filtrate is created from fermenting Saccharomyces, a yeast also known as baker's yeast or brewer's yeast.
As a humectant, Saccharomyces Ferment Filtrate helps draw moisture from the air to your skin to keep your skin hydrated. The humectant properties comes from its beta-glucan content.
Phospholipids are naturally found in our skin as they are the main component of cell membranes. Phospholipids have humectant, emollient, antioxidant properties.
Phospholipids are complex lipids that contain glycerin, two fatty acids, and a phosphate group. Some foods that contain phospholipids include soybeans and milk. The phospholipids found in soy come from Lecithin. This ingredient can also be synthetically created.
Due to their hygroscopic nature, they act as both humectants and emollients. Humectants draw moisture from the air to your skin, while emollients help trap moisture in.
The phospholipids in our skin can be naturally depleted. Replenishing the phospholipids in our skin can help hydrate your skin.
Studies show phospholipids display antioxidant activity and may help with reducing the signs of aging.
This ingredient is non-occlusive.
Some types of phospholipids:
Learn more about PhospholipidsSaccharomyces Lysate Extract is from the yeast Saccharomyces. This ingredient is created from the cell walls of Saccharomyces.
As a humectant, Saccharomyces Lysate Extract helps draw moisture to your skin. This helps keep your skin hydrated.
Saccharomyces is also known as brewer's yeast and was traditionally used to make beer.
Learn more about Saccharomyces Lysate ExtractLecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.
This ingredient has emollient and emulsifying properties.
As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.
As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.
This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.
Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.
We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.
Learn more about LecithinWe don't have a description for Acetyl Glutamine yet.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolBacillus/Folic Acid Ferment Filtrate Extract is an antioxidant.
Sh-Polypeptide-1 is a signal peptide that tells our cells to create more fibroblast cells. Fibroblasts maintain skin structure and plays a role in wound healing.
It is important to note this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.
Sh-Polypeptide-9 is a signal peptide that tells our body to create more blood vessels.
It is important to note, this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.
Sh-Polypeptide-11 is a signal protein that tells our skin to create more fibroblast cells. Fibroblasts maintain skin structure and plays a role in wound healing.
It is important to note this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.
Hydroxyethylcellulose is used to improve the texture of products. It is created from a chemical reaction involving ethylene oxide and alkali-cellulose. Cellulose is a sugar found in plant cell walls and help give plants structure.
This ingredient helps stabilize products by preventing ingredients from separating. It can also help thicken the texture of a product.
This ingredient can also be found in pill medicines to help our bodies digest other ingredients.
Learn more about HydroxyethylcelluloseXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumPentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolCaprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.
Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.
This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.
Learn more about Caprylyl GlycolEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
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Where it's from
Le Mieux is a American brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Published June 24, 2025 • Added by Tartora