What's inside
What's inside
Key Ingredients
Benefits
Concerns
No concerns
Ingredients Side-by-side
Water
Skin ConditioningButylene Glycol
Humectant
Pentylene Glycol
Skin Conditioning
Propanediol
Solvent
Hyaluronic Acid
Humectant
Sodium Hyaluronate
Humectant
Hydrolyzed Hyaluronic Acid
Humectant
Hydrolyzed Sodium Hyaluronate
Skin Conditioning
Oligopeptide-4
Skin Conditioning
Acetyl Hexapeptide-8
Humectant
Acetyl Octapeptide-3
Humectant
Serine
Masking
Glycine
Buffering
Glutamic Acid
Humectant
Aspartic Acid
Masking
Alanine
Masking
Leucine
Skin ConditioningLysine
Skin ConditioningArginine
Masking
Tyrosine
MaskingPhenylalanine
Masking
Proline
Skin Conditioning
Threonine
Valine
MaskingIsoleucine
Skin ConditioningHistidine
Humectant
Caprylyl Glycol
Emollient
Hydroxyacetophenone
Antioxidant
Water, Butylene Glycol, Pentylene Glycol, Propanediol, Hyaluronic Acid, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Oligopeptide-4, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Serine, Glycine, Glutamic Acid, Aspartic Acid, Alanine, Leucine, Lysine, Arginine, Tyrosine, Phenylalanine, Proline, Threonine, Valine, Isoleucine, Histidine, Caprylyl Glycol, Hydroxyacetophenone
Water
Skin ConditioningPropanediol
Solvent
Butylene Glycol
Humectant
Glycerin
Humectant
Pentylene Glycol
Skin Conditioning
Copper Tripeptide-1
Skin Conditioning
Acetyl Hexapeptide-8
Humectant
Acetyl Octapeptide-3
Humectant
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Skin Conditioning
Oligopeptide-1
Skin Conditioning
Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76
Skin Conditioning
Hydrolyzed Hyaluronic Acid
Humectant
Sodium Hyaluronate
Humectant
Caprylyl Glycol
Emollient
Carrageenan
Hydroxyacetophenone
Antioxidant
Water, Propanediol, Butylene Glycol, Glycerin, Pentylene Glycol, Copper Tripeptide-1, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Oligopeptide-1, Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Caprylyl Glycol, Carrageenan, Hydroxyacetophenone
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".
It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.
The comparison to Botox does have limits because the molecule is water-loving and relatively large.
Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.
So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.
A 12 week human study of a multi-ingredient regimen containing this ingredient saw:
While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).
Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.
Learn more about Acetyl Hexapeptide-8Acetyl Octapeptide-3 is a synthetic peptide also commonly known as SNAP-8. It is a lab-made peptide often marketed as a gentler, topical alternative to Botox.
It works by mimicking part of a protein involved in muscle contractions, which may help relax facial tension and reduce the appearance of fine lines (mostly around the eyes and forehead).
It’s considered a “next-gen” version of Argireline (Acetyl Hexapeptide-8), an older peptide with more research behind it that also supports collagen production.
SNAP-8 showed slightly better results than Argireline in one small manufacturer-funded study, but there’s limited independent research. Plus, most tests use concentrations higher than what’s typically found in skincare products.
This ingredient might offer a subtle smoothing effect but it won't don’t deliver the dramatic results of actual Botox injections.
Think of it more like a supporting actor in your skincare lineup.
Learn more about Acetyl Octapeptide-3Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolHydrolyzed Hyaluronic Acid is hyaluronic acid (HA) that is broken down into lower molecular weight fragments.
It's a humectant that pulls and holds water in the skin to help with hydration, plumpness, and reduce transepidermal water loss.
Because hydrolyzed hyaluronic acid is smaller in size, it can slip past your outermost layer of skin more easily than full-sized HA.
Most formulations will combine all sizes to get the best of both worlds.
Typical usage levels range from 0.01-1%. Any percentage higher than 2% might become goopy and tacky.
Learn more about Hydrolyzed Hyaluronic AcidHydroxyacetophenone is a small phenolic molecule that earns its place in a formulas as an antioxidant and preservative booster.
As a phenol, it is able to neutralize free radicals to protect both the product and the skin from oxidative stress.
Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol.
This ingredient naturally occurs as piceol in Norwegian spruce needles (~0.4-1.1% dry weight and in cloudberries). Though the cosmetic-grade material is synthesized for purity and consistency.
You'll usually see it used at low levels and suppliers recommend up to 1% added to a water phase.
Safety testing was done at concentrations like 0.05% in SPF products and 0.5% in a Human Repeated Insult Patch Test. The safety evidence is assuring; this ingredient is safe for cosmetics in current use and also holds safety status as a food flavoring as well.
An honest caveat: the "soothing" and "anti-inflammatory" claims come mostly from supplier marketing rather than published clinical trials. The Cosmetic Ingredient Review's own literature search found no useful efficacy studies on this ingredient.
So the antioxidant and preservative-boosting roles are the well supported ones while the calming benefit is plausible but thinly evidenced.
Overall, this is a well-tolerated, low-irritation multitasker that quietly helps a formula stay fresh and stable.
Learn more about HydroxyacetophenonePentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Learn more about Pentylene GlycolPropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water
