Overview
What it is
Serum with 18 ingredients
Cool Features
It is fungal acne (malassezia) safe and reef safe
Suited For
It has ingredients that are good for dry skin and scar healing
Free From
It doesn't contain any harsh alcohols, oils, parabens, silicones or sulfates
Fun facts
SkinMedica is from United States. This product is used in 98 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Human Neonatal Fibroblast Conditioned Media
Skin ConditioningIsoceteth-20
EmulsifyingEthoxydiglycol
HumectantAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingAminomethyl Propanol
BufferingDisodium EDTA
Ethylhexylglycerin
Skin ConditioningGlycerin
HumectantCaprylyl Glycol
EmollientCaprylhydroxamic Acid
Phenoxyethanol
PreservativeParfum
MaskingHydroxycitronellal
PerfumingLinalool
PerfumingCoumarin
PerfumingAlpha-Isomethyl Ionone
PerfumingGeraniol
PerfumingIsoeugenol
PerfumingHuman Neonatal Fibroblast Conditioned Media, Isoceteth-20, Ethoxydiglycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Aminomethyl Propanol, Disodium EDTA, Ethylhexylglycerin, Glycerin, Caprylyl Glycol, Caprylhydroxamic Acid, Phenoxyethanol, Parfum, Hydroxycitronellal, Linalool, Coumarin, Alpha-Isomethyl Ionone, Geraniol, Isoeugenol
Benefits
Concerns
Ingredients Explained
This is a growth factor ingredient. Growth factors stimulate cell growth and healing.
Studies find they help with:
The term "conditioned media" refers to a mix of lab grown growth-factors. Just so you know - the US allows human-derived growth factors. However, human-derived growth factors are illegal in the EU and plant sources are used as an alternative.
According to Dr. Zoe Draelos, growth factors have some drawbacks:
However, many people have seen great results from using growth factor serums.
There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer.
Learn more about Human Neonatal Fibroblast Conditioned MediaIsoceteth-20 comes from Isocetyl Alcohol. It is an emulsifier. Emulsifiers help stabilize a product. It does this by preventing certain ingredients from separating.
Ethoxydiglycol is a synthetic solvent.
Solvents are used to keep ingredients together in a product. They can help dissolve ingredients to stable bases or help evenly distribute ingredients throughout the product.
Ethoxydiglycol also helps deliver other key ingredients into the skin.
Learn more about EthoxydiglycolAcrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
Learn more about Acrylates/C10-30 Alkyl Acrylate CrosspolymerAminomethyl Propanol is used to adjust the pH of products. It is also used as a base to create other organic compounds. Having a balanced pH is important for protecting your skin.
Aminomethyl propanol is safe to use in cosmetics up to 1%. It is soluble in water.
Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolCaprylhydroxamic Acid is a chelating agent that helps cosmetics stay fresh, stable, and consistent over time.
Chelating agents help prevent metal ions from binding to other ingredients. This helps prevent unwanted reactions and effects from using the product. It also helps prevent the growth of unwanted microbes in products that contain water.
Caprylhydroxamic Acid is often used with natural antimicrobial products as an alternative to preservatives.
Learn more about Caprylhydroxamic AcidPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumHydroxycitronellal is a fragrance created from citronellal. The smell of hydroxycitronellal is often described as "citrus-like" or "melon-like".
Hydroxycitronellal is a known EU allergen and may cause irritation when applied to the skin.
Linalool is a fragrance and helps add scent to products. It's derived from common plants such as cinnamon, mint, citrus, and lavender.
Like Limonene, this ingredient oxidizes when exposed to air. Oxidized linalool can cause allergies and skin sensitivity.
This ingredient has a scent that is floral, spicy tropical, and citrus-like.
Learn more about LinaloolCoumarins are a group of substances found naturally in plants. There are over 1300 types of coumarins identified. It has a natural vanilla scent.
Coumarin is an identified EU known allergy, meaning it may cause an allergic reaction when applied to the skin.
In many countries, coumarin is banned as a food additive. However, it can be found in soaps, tobacco products, and some alcohol drinks.
Plants use coumarins as a chemical defense. Some plants that have coumarins include lavender, tonka beans, and yellow clovers.
Learn more about CoumarinAlpha-Isomethyl Ionone is a fragrance. It can be synthetically created or naturally occurring.
The scent of Alpha-Isomethyl Ionone is described as "flowery" but can also be "woody".
Naturally occurring Alpha-Isomethyl Ionone may be found in Saccharomyces cerevisiae, or the yeast used to make wine and bread.
The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.
Learn more about Alpha-Isomethyl IononeGeraniol is used to add fragrance/parfum to a product. It is the main component of citronellol. It is a monoterpenoid and an alcohol.
Monoterpenes are naturally found in many parts of different plants.
Geraniol can be found in many essential oils including Rose Oil and Citronella Oil. The scent of Geraniol is often described as "rose-like". Many foods also contain Geraniol for fruit flavoring.
Geraniol can irritate the skin when exposed to air. However, irritation depends on the ability of geraniol to penetrate into the skin. In general, geraniol is not able to penetrate skin easily.
Geraniol is colorless and has low water-solubility. However, it is soluble in common organic solvents.
Like citronellol, it is a natural insect repellent.
2,6-Octadien-1-ol, 3,7-dimethyl-, (2E)-
Learn more about GeraniolIsoeugenol is a fragrance component that is naturally occurring in plants such as ylang-ylang, nutmeg, and cinnamon.
Isoeugenol is a known EU allergen. This means it is known to cause an allergic reaction when applied to the skin.
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Where it's from
SkinMedica is a American brand
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The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Published March 23, 2023 • Added by Am96815