Nacomi Next Level Bakuchiol 2%

On top of that, soybean oil is rich in vitamins like vitamin E, a potent antioxidant.

Research on soybean's active components also point to anti-inflammatory, collagen-stimulating, antioxidant activity, and protection against UV-induced oxidative damage.

Most of this research applies to the broader soybean plant and not just the oil fraction alone.

This ingredient may not be fungal acne safe due to the oleic acid content.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

1) produce more collagen (type I, III, and IV)
2) activate the same genes retinoids do

Unlike retinoids, this ingredient will not increase photosensitivity and is safe to use during pregnancy (but please still check in with your doctor!).

The flagship clinical trial from Dhaliwal et al. 2019 found 0.5% bakuchiol (twice daily) and 0.5% retinol (once daily) reduced wrinkles and hyperpigmentation equally, but bakuchiol had significantly less irritation.

Systematic reviews also back this up:

Bakuchiol is comparable to retinol for photoaging but with better tolerability. It also has mild antibacterial properties against Cutibacterium acnes and antifungal activity in vitro against Candida and dermatophytes.

The reason bakuchiol works well is due to its structure; it is a meroterpene phenol, or a hybrid molecule. The phenol half acts as an antioxidant while the terpene half is fat-loving. This helps the molecule slip through the skin barrier.

This ingredient is usually used between 0.5-2%. Only one case of contact dermatitis has ever been reported for this ingredient.

These fatty acids are very similar to those naturally found in the epidermis, making this oil biomimetic; basically, your skin recognizes it.

Clinical testing found this ingredient to be moisturizing and non-irritating, with noteworthy effects on reducing transepidermal water loss (TEWL).

Besides fatty acids, marula oil is also rich in oxidative stabilizers like vitamin E, vitamin C precursors, and polyphenols. This gives it excellent shelf stability compared to most facial oils.

This is a great ingredient for dry, dull, or barrier-compromised skin.

Just know it may not be fungal acne safe due to the oleic and palmitic acid content. These fatty acids can as as a food source for the Malassezia yeast.

It is generally considered low risk when used at the small amounts typical in cosmetics. However, it may still bother fragrance-sensitive skin because it’s a fragrant botanical.

Unlike some citrus peel oils, bitter orange flower extracts are not usually linked to sun sensitivity.

This ingredient can also help mask unpleasant scents from other ingredients.

Rosmarinic acid has been shown to calm inflammation signaling in skin cells (the same pathways that flare up in conditions like eczema and psoriasis). It also has real antimicrobial and antifungal activity in test-tube studies.

This ingredient is typically used in low concentrations (generally well under 1%) where it acts as a light fragrance + mild skin soother extract.

The main thing to know is that lavender contains two naturally fragrant molecules: Linalool and Linalyl Acetate. Some people's skin does perfectly fine with fragrance while others don't.

Just be sure to patch test if you have reactive skin or known plant allergies.

Linalool and Linalyl Acetate are gentle when fresh but oxidize into compounds that can cause allergic contact dermatitis when exposed to air. Patch-test studies of patients already being investigated for skin allergies found about 5-7% of patients had reactions to oxidized linalool, and 2.8% of patients reacted to oxidized lavender oil.

In lab studies, peony flower extracts show antioxidant activity and can reduce stress response in keratinocytes, the main skin cell found in the epidermis.

Other major parts of Rose Oil include citronellol and geraniol. Both of these are known EU allergens and cause contact-allergies.

The downsides of this ingredient outweight the positives.

The reason this ingredient is so effective is because it forms a thin film on the skin that reduces transepidermal water loss (TEWL) while supplying linoleic acid to the stratum corneum to improve barrier strength.

The high linoleic acid content is particularly noteworthy for acne-prone skin.

Research suggests that acne-prone skin tends to be deficient in linoleic acid in sebum. Topical application may help replenish this to support a healthier follicular environment and less comedone-promoting sebum.

One randomized study found sunflower seed oil preserved skin barrier integrity in adult volunteers with and without atopic dermatitis (outperforming olive oil).

This ingredient is well-studied, gentle, and an effective emollient suitable for most skin types.

On fungal acne: This ingredient may not be Fungal acne (Malassezia folliculitis) safe. This is because it contains fatty acids with carbon chain lengths in the C11-C24 range.