Overview
What it is
Ampoule with 20 ingredients
Cool Features
It is fungal acne (malassezia) safe and reef safe
Suited For
It has ingredients that are good for fighting acne, dry skin, oily skin and scar healing
Free From
It doesn't contain any harsh alcohols, common allergens, parabens, silicones or sulfates
Fun facts
Mediheal is from South Korea. This product is used in 78 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Melaleuca Alternifolia Leaf Water
AntimicrobialGlycerin
HumectantPropanediol
SolventMethylpropanediol
SolventMelia Azadirachta Leaf Extract
Skin ConditioningMelia Azadirachta Flower Extract
Skin ConditioningTheobroma Cacao Seed Extract
AntioxidantMelaleuca Alternifolia Leaf Extract
PerfumingMelaleuca Alternifolia Leaf Oil
AntioxidantHydrogenated Lecithin
EmulsifyingAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingDiethoxyethyl Succinate
SolventDisodium EDTA
Tromethamine
BufferingWater
Skin ConditioningDextrin
Absorbent4-Terpineol
MaskingLactobacillus Ferment
Skin Conditioning1,2-Hexanediol
Skin ConditioningEthylhexylglycerin
Skin ConditioningMelaleuca Alternifolia Leaf Water, Glycerin, Propanediol, Methylpropanediol, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Theobroma Cacao Seed Extract, Melaleuca Alternifolia Leaf Extract, Melaleuca Alternifolia Leaf Oil, Hydrogenated Lecithin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Diethoxyethyl Succinate, Disodium EDTA, Tromethamine, Water, Dextrin, 4-Terpineol, Lactobacillus Ferment, 1,2-Hexanediol, Ethylhexylglycerin
Key Ingredients
Benefits
Concerns
Ingredients Explained
This ingredient is created by distilling parts of the tea tree plant. The bark and leaves of the tea tree plant are rich in Terpinen, an antioxidant, antibacterial, and anti-inflammatory ingredient.
Tea tree may cause sensitivity and irritation for some people due to its linalool and limonene content.
Learn more about tea tree benefits here.
Learn more about Melaleuca Alternifolia Leaf WaterGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolMethylpropanediol is a synthetic solvent and humectant.
As a solvent, it helps dissolve other ingredients, helping to evenly distribute ingredients throughout the product. This ingredient has also been shown to have antimicrobial properties which makes it a preservative booster.
Methylpropanediol is able to add a bit of moisture to the skin. It also helps other ingredients be better absorbed into the skin, such as salicylic acid.
Learn more about MethylpropanediolMelia Azadirachta Leaf Extract is extract from the neem plant.
The leaves of this tree contain flavonoids and polyphenols. These two compounds are antioxidants, anti-inflammatory, and antibacterial. Further research is needed as to their effects when applied on skin.
Melia Azadirachta Flower Extract is from the Neem tree. Neem trees originate from India.
Melia Azadirachta Flower Extract contains antioxidants. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.
The flowers of this tree are lilac colored.
Learn more about Melia Azadirachta Flower ExtractTheobroma Cacao Seed Extract comes from the Theobroma cacoa, or Cacao tree. Cacao trees are native to tropical landscapes.
Cacao seed extract contains antioxidants known as polyphenols.
Melaleuca Alternifolia Leaf Extract comes from the Tea Tree, Melaleuca alternifolia, Myrtaceae. This tea tree is native to Australia.
Tea Leaf extract contains antimicrobial and anti-acne properties.
This ingredient has perfuming properties and contains linalool and limonene. These fragrance and terpinen components can cause skin sensitivity.
Learn more about the benefits of Tea Tree Oil here.
Learn more about Melaleuca Alternifolia Leaf ExtractThis tea tree oil comes from the leaves of the Tea Tree plant. Tea tree oil has antioxidant, anti-inflammatory, and antimicrobial properties.
According to the book Journal of Profiles of Drug Substances, tea tree helps in reducing acne-causing bacteria such as Propionibacterium acnes. This is due to the Terpinen components of tea tree oil.
Tea tree may cause sensitivity and irritation for some people. This oil naturally contains fragrance such as linalool and limonene.
However, research shows irritation usually occurs when using pure tea tree oil and not in cosmetic products.
Tea tree oil was found to help relieve the symptoms of psoriasis in one study.
Tea tree oil is toxic when ingested. Another study showed it to caused damage to the nervous system of dogs and cats when applied to their skin or given orally.
Learn more about Melaleuca Alternifolia Leaf OilHydrogenated Lecithin is a more stable version of lecithin.
It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.
This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.
Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.
A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).
Learn more about Hydrogenated LecithinAcrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
Learn more about Acrylates/C10-30 Alkyl Acrylate CrosspolymerWe don't have a description for Diethoxyethyl Succinate yet.
Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTATromethamine helps balance the pH and improve the texture of a product. It is synthetically created.
As an emulsifier, Tromethamine prevents oil and water ingredients from separating. This helps stabilize the product and elongate a product's shelf life. Tromethamine also makes a product thicker.
Tromethamine helps balance the pH level of a product. Normal pH level of skin is slightly acidic (~4.75-5.5). The acidity of our skin is maintained by our glands and skin biome. Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.
Oral Tromethanmine is an anti-inflammatory drug but plays the role of masking, adding fragrance, and/or balancing pH in skincare.
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-
Learn more about TromethamineWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterDextrin is used to thicken a product and helps bind ingredients together. It is created from starch and glycogen.
As an emulsifier, dextrin prevents ingredients from separating. This helps elongate a product's shelf life.
Studies show coating UV filters with dextrin prevents these ingredients from being absorbed. This helps UV ingredients last longer on the skin.
Learn more about Dextrin4-Terpineol is the main component of tea tree oil. It has antibacterial, antioxidant, and anti-inflammatory properties.
This ingredient is potent at killing bacteria, making it an effective acne treatment. According to the book Journal of Profiles of Drug Substances, it helps in reducing acne-causing bacteria such as Propionibacterium acnes.
While tea tree has been found to help soothe inflammation and redness, it can also cause sensitivity and irritation in some people.
Research shows irritation usually occurs when using pure oil and not from cosmetic products.
This ingredient can be derived from several parts of the tea tree plant: leaves, branches, and bark.
Learn more about 4-TerpineolThis ingredient is made when the Lactobacillus bacteria (the same kind that makes yogurt and kimchi) are allowed to ferment a nutrient medium.
As it ferments, it collects lactic acid, peptides, enzymes, and other bioactive metabolites to provide:
A 2023 review noted that probiotic fermentation ingredients like this one can enhance antioxidant capacity, reduce UV-induced oxidative damage, and support barrier function.
One clinical study from the same year showed a Lactobacillus ferment lysate significantly reduced transepidermal water loss and improved skin hydration.
Another review highlighted that topical Lactobacillus-based preparations can improve ceramide levels in the stratum corneum, support barrier integrity, and even help reduce S. aureus colonization in atopic dermatitis.
Why is this so cool?
Basically, your skin's outer layer works as a brick wall; skin cells are bricks and ceramides are the mortar holding it together. Moisture escapes, irritants get in, and your skin gets dry and reactive when ceramide levels drop. On top of that, "bad" skin bacteria S. aureus loves to move in when your barrier is weak to make inflammation and irritation worse.
So Lactobacillus ferment is basically patching the wall and evicting the troublemaker when it boosts ceramide production and help keep S. aureus in check.
On top of all this, it also acts as a mild antimicrobial preservative booster.
Just so you know, most studies focus on specific strains or the lysate form rather than this generic "Lactobacillus Ferment", so results can vary.
Though it's a promising ingredient, it doesn't have decades of robust clinical data behind it just yet.
Lactobacillus Ferment is generally considered safe for fungal-acne prone skin. The key thing to understand is that it comes from bacteria, not yeast or fungus.
Yeast-derived ferments (like galactomyces) have been shown to activate a protein that's linked to Malassezia-related skin issues whereas lactobacillus doesn't have that problem.
Its byproducts also don't contain the types of fatty acids (C11-24 chain lengths) that Malassezia feeds on.
Learn more about Lactobacillus Ferment1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinReviews
Where it's from
Mediheal is a Korean brand
Often compared with
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated November 8, 2023 • Added by weird_skin