Garden of Wisdom Synergistic Anti-Inflammatory Niacinamide And B-5 Serum
A serum with 9 ingredients, including niacinamide.
This calming serum is formulated around Niacinamide to calm redness and strengthen the skin barrier.
We independently verify ingredients, backed by peer-reviewed research. Suggest an update.
What's inside
Key Ingredients
Benefits
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterPersea Gratissima Fruit Extract comes from the avocado.
Avocados are rich in fatty acids. About 67% of these fatty acids is made up of oleic acid. Palmitic acid and linoleic acid are also present.
Besides fatty acids, avocados also have B vitamins, vitamin K, vitamin C, vitamin E, and potassium.
Learn more about Persea Gratissima Fruit ExtractPantothenic Acid is also known as Vitamin B5. It is a water-soluble vitamin with skin hydrating and soothing properties.
Research shows pantothenic acid help support the skin's natural barrier by improving moisture retention. This is why you'll likely find this ingredient in soothing products or formulations for sensitive skin.
Some studies have explored oral supplementation of pantothenic acid in the acne context and found it to help reduce blemishes over time.
Though oral and topical use are different, this research helps explain why vitamin B5 is often included in skincare routines aimed at keeping skin balanced and hydrated.
Learn more about Pantothenic AcidHelianthus Annuus Extract comes from the common sunflower.
Sunflowers are rich in vitamin E. Studies show sunflowers contain antimicrobial and antioxidant properties.
The fatty acids found in sunflowers include (from highest amount to least): linoleic acid, myristic acid, palmitic acid, stearic acid, arachidic acid, oleic acid, and linolenic acid.
These fatty acids hydrate your skin. Emollients create a film on the skin to prevent moisture from escaping.
Learn more about Helianthus Annuus ExtractNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideWe don't have a description for Populus Tremuloides Bark Extract yet.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumPolyaminopropyl Biguanide is a preservative.
We don't have a description for Citrus Nobilis Fruit Extract yet.
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Where it's from
Garden of Wisdom is a American brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated January 28, 2026 • Added by evelynedwards