Aspen Pharmacare Evalon Estriol Cream BP
A prescription with 12 ingredients.
Prescription with 12 ingredients
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What's inside
Ingredients List
Estriol 0.1%
Octyldodecanol
EmollientCetyl Palmitate
EmollientGlycerin
HumectantCetyl Alcohol
Emollient
Active Ingredients:
Estriol 0.1%
Inactive Ingredients:
Octyldodecanol, Cetyl Palmitate, Glycerin, Cetyl Alcohol, Stearyl Alcohol, Polysorbate 60, Sorbitan Stearate, Lactic Acid, Chlorhexidine Dihydrochloride 0.01%, Sodium Hydroxide, Water
Benefits
Ingredients Explained
Estriol, also called oestriol, is a steroid and a weak form of estrogen. This is not an INCI ingredient and we suggest speaking with a medical professional about using this ingredient.
Octyldodecanol is a fatty alcohol sourced from plant oils like coconut or palm (or made synthetically).
It is:
You'll likely see this in many BHA products because this is the go-to solvent for salicylic acid.
This ingredient is typically used at levels between 2-20%.
Regarding fungal acne:
In 2019, this ingredient was tested against multiple Malassezia species (the yeast that causes fungal acne) and showed no growth.
Cetyl Palmitate is a wax-ester that pulls triple duty as an emollient, thickener, and emulsion enhancer.
It helps enhance the texture of products by giving a smooth, silky feel while helping to stabilize the formula. The emollient action softens skin and reduces moisture loss.
This ingredient is considered safe and human testing of concentrations between 2.5-2.7% were found minimal irritation. Just know, there have been very rare cases of the palmitate family causing contact dermatitis.
This ingredient may not be fungal acne safe because it contains a C16 ester (palmitic acid) that falls into the C11-24 range that Malassezia can feed on.
Learn more about Cetyl PalmitateGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinCetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.
Its main roles are:
Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.
The FDA allows products labeled "alcohol-free" to have fatty alcohols.
This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.
Learn more about Cetyl AlcoholStearyl Alcohol is a type of fatty alcohol from stearic acid. It is a white, waxy compound used to emulsify ingredients used as an emollient or to thicken a product.
Emollients help soothe and hydrate the skin by trapping moisture.
Fatty alcohols are usually derived from natural fats and oils and therefore do not have the same drying or irritating effect as solvent (ethanol) alcohols.
The FDA allows products labeled "alcohol-free" to have fatty alcohols.
This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.
Learn more about Stearyl AlcoholPolysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.
Polysorbate 60 is sorbitol-based and created from the ethoxylation of sorbitan. Ethoxylation is a chemical reaction used to add ethylene oxide. Sorbitan is a the dehydrated version of sorbitol, a sugar found in fruits.
In this case, the 60 comes from reacting 60 units of ethylene oxide with sorbitan.
Polysorbates are commonly used in medicine and foods.
Learn more about Polysorbate 60Sorbitan Stearate is an emulsifier made by reacting sorbitol with stearic acid.
It's mostly used to keep oil and water mixed so your formulas stay smooth and stable.
The Cosmetic Ingredient Review has found 4% of this ingredient in repeat-insult patch tests on humans to be non-sensitizing. There is a caveat that some reactions have shown up in patients with damaged or diseased skin.
Because it is an ester of a C18 fatty acid, it falls into the C11-24 range that the Malassezia yeast can metabolize. This means this ingredient may not be fungal acne safe.
Learn more about Sorbitan StearateLactic Acid is another well-loved alpha hydroxy acid (AHA). It is gentler than glycolic acid but still highly effective.
Its main role is to exfoliate the surface of the skin by loosening the “glue” that holds dead skin cells together. Shedding those old cells leads to smoother, softer, and more even-toned skin.
Because lactic acid molecules are larger than glycolic acid, they don’t penetrate as deeply. This means they’re less likely to sting or irritate, making it a great choice for beginners or those with sensitive skin.
Like glycolic acid, it can:
Lactic acid also acts as a humectant (like hyaluronic acid). It can draw water into the skin to improve hydration and also plays a role in the skin's natural moisturizing factor (NMF) in the form of sodium lactate.
Studies show it can boost ceramide production to strengthen the skin barrier and even help balance the skin’s microbiome.
To get results, choose products with a pH between 3-4.
Lower strengths (5-12%) focus on surface exfoliation; higher strengths (12% and up) can reach deeper in the dermis (deeper, supportive layer) to improve skin texture and firmness over time.
Though it was originally derived from milk, most modern lactic acid used in skincare is vegan. It is made through non-dairy fermentation to create a bio-identical and stable form suitable for all formulations.
When lactic acid shows up near the end of an ingredient list, it usually means the brand added just a tiny amount to adjust the product’s pH.
Legend has it that Cleopatra used to bathe in sour milk to help reduce wrinkles.
Lactic acid is truly a gentle multitasker: it exfoliates, hydrates, strengthens, and brightens. It's a great ingredient for giving your skin a smooth, glowing, and healthy look without the harshness of stronger acids.
Read more about some other popular AHA's here:
Learn more about Lactic AcidChlorhexidine Dihydrochloride is a preservative.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterReviews
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Where it's from
Aspen Pharmacare is a South African brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated August 7, 2026 • Added by patrick11