Apostrophe Custom Prescription
A prescription with 16 ingredients, including retinoid and vitamin E.
Overview
What it is
Prescription with 16 ingredients that contains retinoid and Vitamin E
Cool Features
It is reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens or sulfates
Fun facts
Apostrophe is from United States. This product is used in 5 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Ingredients List
Tretinoin 0.018%
Skin ConditioningSpironolactone 5%
Clindamycin 1%
BHT
AntioxidantDisodium EDTA
Sodium Metabisulfite
AntioxidantPropylene Glycol
HumectantAloe Barbadensis Leaf Juice
Skin ConditioningCyclopentasiloxane
EmollientEmulsifying Wax Nf
Ethylhexyl Stearate
EmollientMethylchloroisothiazolinone
PreservativeMethylisothiazolinone
PreservativeSorbitol
HumectantTocopheryl Acetate
AntioxidantWater
Skin Conditioning
Active Ingredients:
Tretinoin 0.018%, Spironolactone 5%, Clindamycin 1%
Inactive Ingredients:
BHT, Disodium EDTA, Sodium Metabisulfite, Propylene Glycol, Aloe Barbadensis Leaf Juice, Cyclopentasiloxane, Emulsifying Wax Nf, Ethylhexyl Stearate, Methylchloroisothiazolinone, Methylisothiazolinone, Sorbitol, Tocopheryl Acetate, Water
Key Ingredients
Benefits
Concerns
Ingredients Explained
Tretinoin is the best retinoid due to its proven skin benefits. It only available with a prescription in many countries.
All retinoids goes through a conversion line until it can become effective. The final step of conversion is retinoic acid; retinoic acid IS Tretinoin.
This is why tretinoin is so effective; it gets to work immediately on the skin.
Research on tretinoin has found it to be incredibly effective for reducing the signs of aging. It helps improve damage from the sun, even the skin tone, and smooth out wrinkles. It is also an effective acne treatment by reducing and balancing out sebum production in pores.
Tretinoin, like other forms of Vitamin A, increases the turnover cycle of skin cells. This helps the skin create newer and healthier skin cells faster.
It can cause irritation, redness, and dry skin because it is considered a "strong" ingredient. Those with sensitive skin should consult a professional about using tretinoin.
Using retinoids will increase sun-sensitivity in the first few weeks of use. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.
Read about a form of retinoid you can purchase at the store, retinol.
Learn more about TretinoinThis is not an official INCI ingredient. It is prescription medication.
Please consult with a medical professional about using this ingredient.
Clindamycin is a prescription lincosamide antibiotic used in topical acne treatments to kill acne-causing bacteria (C. acnes) and reduce inflammation.
It's generally found in prescription products rather than standard over-the-counter cosmetics.
BHT is a synthetic antioxidant and preservative.
As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.
As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.
The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.
However, it was recently restricted for use in the UK as of April 2024.
Learn more about BHTDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTASodium metabisulfite is also known as Sodium Pyrosulfite. It is a preservative, antioxidant, and disinfectant.
As a preservative, it helps stabilize cosmetic formulas without affecting their color or scent.
Propylene Glycol is a synthetic, colorless, odorless liquid that has been a staple in cosmetics for decades. It is a skin conditioning agent, humectant, and solvent.
As a humectant, it draw water to the skin to reduce flaking and restore suppleness. It's also a solvent that helps dissolve other actives and keeps formulas stable across temperature changes.
The CIR Expert Panel has confirmed this ingredient to be nontoxic and clinical studies show no sensitization at cosmetic use concentrations.
True allergic reactions are quite rare: a 15-year retrospective study of 6,751 patients found only 0.31% had a positive reaction (and less than half were considered clinically relevant).
It seemed that when sensitization does occur, it's most commonly linked to topical medication (like corticosteroids) and not cosmetics. Allergic contact dermatitis also appears largely limited to individuals with underlying skin conditions.
Overall, propylene glycol is a well-studied ingredient that most people can tolerate without issue.
Learn more about Propylene GlycolAloe Barbadensis Leaf Juice comes from leaves of the aloe plant. Aloe Barbadensis Leaf Juice is best known for helping to soothe sunburns. It is also anti-inflammatory, moisturizing, antiseptic, and can help heal wounds.
Aloe is packed with good stuff including Vitamins A, C, and E. These vitamins are antioxidants, which help fight free-radicals and the damage they may cause. Free-radicals are molecules that may damage your skin cells, such as pollution.
Aloe Barbadensis Leaf Juice also contains sugars. These sugars come in the form of monosaccharides and polysaccharides, folic acid, and choline. These sugars are able to help bind moisture to skin.
It also contains minerals such as calcium, 12 anthraquinones, fatty acids, amino acids, and Vitamin B12.
Learn more about Aloe Barbadensis Leaf JuiceCyclopentasiloxane, or D5, is a silicone used to improve texture of products and trap moisture.
D5 is considered lightweight and volatile. Volatile means it evaporates quickly after application. Once evaporated, D5 leaves a thin barrier that helps keep skin hydrated.
It is also an emollient. Emollients help soften the skin and prevent water loss. Silicones create a silky texture in products. D5 helps other ingredients become more spreadable.
Studies show D5 is safe to use in skincare products. We recommend speaking with a skincare professional if you have concerns.
Learn more about CyclopentasiloxaneThis is not considered an INCI ingredient.
Emulsifying Wax NF is about 2/3 cetearyl alcohol and 1/3 polysorbate 60. In cosmetics, this blend is usually listed out as the individual ingredients.
The NF stands for National Formulary, meaning it conforms to the approved composition.
This ingredient is used as an emulsifier. It stabilizes the product by keeping oils and waters together.
Learn more about Emulsifying Wax NfEthylhexyl Stearate mainly acts as an emollient that helps hydate skin. It can also be used to reduce the greasiness of oils in a formula.
Because this ingredient contains a C18 fatty acid chain, it may not be Malassezia/fungal acne safe. This is because the Malassezia yeast potentially feeds on C11-C24 fatty acids.
This ingredient is an ester of 2-ethylhexyl alcohol and stearic acid.
Learn more about Ethylhexyl StearateMethylchloroisothiazolinone, or MCI, is a synthetic preservative used to protect against the growth of bacteria, yeasts, and fungi in water-based products.
MCI is commonly combined with methylisothiazolinone (MI) in a 3:1 ratio.
This ingredient is safe in cosmetics when formulated to be non-sensitizing and concentrations must not exceed 7.5 ppm in leave-on products / 15 ppm in rinse-off products.
Unfortunately, this ingredient has a well-documented sensitization story. Studies spanning several decades have shown this ingredient + MI to cause skin irritation and allergies.
The use of this ingredient varies around the world:
This just means this ingredient is most likely non-sensitizing in rinse-off products unless you've been diagnosed with a contact allergy to isothiazolinones.
Learn more about MethylchloroisothiazolinoneMI is a preservative and known skin irritant. In the past, MI was used for its ability to prevent bacteria, yeast, and fungi growth in low doses.
Nowadays, you'll most likely see MI combined with Methylchloroisothiazolinone (MCI).
Since then, numerous studies have shown this ingredient to cause contact dermatitis, or skin irritation.
The use of this ingredient varies around the world:
Learn more about MethylisothiazolinoneSorbitol is a sugar alcohol. It is a hydrating and moisturizing agent created from the reduction process of glucose.
Most sorbitol is usually made from potato starch. It is also found in fruits such as apples and pears.
As a humectant, Sorbitol helps draw water to the skin. This helps keep the skin hydrated. Sorbitol also helps create a thicker texture in products. You might find sorbitol in your toothpaste and other gels.
It is a non-irritating ingredient that is great for those with dry skin.
Sorbitol is a prebiotic. It helps promote the growth of healthy bacteria on your skin. The bacteria on your skin form a microbiome. This microbiome helps protect your skin from infection and harmful bacteria.
Learn more about SorbitolTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterReviews
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Where it's from
Apostrophe is a American brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about usยท Updated August 5, 2024 • Added by katebracken