Amzeeq (Minocycline) Topical Foam, 4%

A double-blind study confirmed that extra virgin coconut oil is as effective as mineral oil for treating very dry skin. Another study found it outperformed mineral oil for mild to moderate atopic dermatitis in children.

Another study from 2018 found that virgin coconut oil can soothe inflammation and boost key skin barrier proteins. Just know this evidence is still only from lab settings and not human trials.

It has also been shown to reduce Staphylococcus aureus, a bacteria that commonly overgrows in people with eczema.

Clinical testing shows very minimal skin irritation and no evidence of sensitization or phototoxicity.

Coconut oil gets flagged as a "fragrance" because it has a natural mild scent (not because it's a synthetic perfume). The European Cosmetic ingredient database also lists "perfuming" as a function of this ingredient.

Just so you know, the term "fragrance" is completely unregulated. Some brands still use botanical extracts or essential oils in their "fragrance-free" formulas, but regulatory databases technically classify these under "fragrance".

Coconut oil has a tiny and useless bit of natural SPF. Early lab studies clocked it around SPF 7-8 but a more recent study found the real number closer to SPF 1.2. It also offers no meaningful UVA protection (SPF only overs UVB rays).

The comedogenic rating of 4/5 means it has a high potential to clog pores; but it's worth noting that comedogenicity is highly individual and ratings cannot predict how an overall formula will behave on skin.

Since lauric acid is the dominant fatty acid, this ingredient may not be fungal acne safe. The Malassezia yeast feeds on fatty acids with carbon chain lengths between 11-24, and lauric acid falls within these lengths (C12).

As an occlusive, it forms a protective layer on the skin that locks in moisture and prevents transepidermal water loss (TEWL). This makes it especially great for compromised skin barriers.

The "it clogs your pores" myth has been around for decades; a study found that industrial-grade mineral oil may be comedogenic but cosmetic-grade mineral oil is not (these two are very, very different).

A 2017 review concluded that cosmetic use of mineral oils and waxes does not present a risk to consumers due to absorption.

Mineral oil got a bad rap from the old rabbit ear studies. When tested on actual human skin, cosmetic-grade mineral oil showed no comedogenic activity. The rating of 0 is a correction of outdated science.

Mineral oil is an inert substance with no fatty acids so there's nothing to feed Malassezia. This ingredient is fungal acne safe.

The most popular types of cyclomethicones include D5 and D6.

It plays several roles in a formula:

Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.

Multiple assessments have found it to be non-irritating and non-sensitizing to most people.

However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.

Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.

Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.

Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.

This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.

A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.

Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.

Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.

Fatty alcohols are usually derived from natural fats and oils and therefore do not have the same drying or irritating effect as solvent alcohols.

The FDA allows "alcohol-free" products to contain fatty alcohols.

According to EU CosIng, this ingredient helps soften skin, keep oil and water stay mixed, and thickens products.

Hydrogenated castor oil at 30% did not trigger a positive patch-test reaction and is well-tolerated.

Since this ingredient is based on an 18-carbon fatty acid, it falls into the chain-length range that Malassezia can feed on and may not be fungal acne safe.

Emulsifiers help prevent ingredients from separating. This helps create consistent texture.

The structure of beeswax is mainly long-chain alcohols and the esters of fatty acids.

There are three types of beeswax: yellow, white, and absolute. Yellow is pure beeswax taken from the honeycomb. White beeswax is created by filtering or bleaching yellow beeswax. Absolute beeswax is created by treating beeswax with alcohol. Beeswax used in cosmetics are purified.

Beeswax has been used throughout history and even in prehistoric times. Some common uses for beeswax still used today are making candles, as a waterproofing agent, and polish for leather.

Fatty alcohols are usually derived from natural fats and oils and therefore do not have the same drying or irritating effect as solvent (ethanol) alcohols.

The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.

Emollients help keep your skin soft and hydrated by creating a film that traps moisture in.

In 2000, Behenyl Alcohol was approved by the US as medicine to reduce the duration of cold sores.

If it does somehow make it onto your skin, it is chemically inert and does not penetrate or get absorbed into skin. Safety assessments note that adverse skin reactions to this ingredient are uncommon.

It is volatile, meaning it only remains on skin for less than 10 seconds before evaporating. It doesn't really linger long enough on skin to act as a skincare ingredient in any meaningful way.

Hairspray concentrations are between 6-17%.

The CIR Expert Panel concluded it to be safe as a cosmetic ingredient under present concentration and usage.