This anti-aging treatment is formulated around Sh-Oligopeptide-1 and Acetyl Hexapeptide-8 to soften the look of wrinkles and refine skin texture.
This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-1 to soften the look of wrinkles and refine skin texture.
What's inside
What's inside
Key Ingredients
Benefits
Ingredients Side-by-side
Water
Skin ConditioningSh-Oligopeptide-1
Skin Conditioning
Sh-Oligopeptide-2
Skin Conditioning
N-Prolyl Palmitoyl Tripeptide-56 Acetate
Skin Conditioning
Sh-Polypeptide-1
Skin Conditioning
Sh-Polypeptide-9
Skin Conditioning
Tetrapeptide-21
Skin Conditioning
Caprooyl Tetrapeptide-3
Skin Protecting
Acetyl Hexapeptide-8
Humectant
Acetyl Hexapeptide-38
Skin Conditioning
Palmitoyl Tripeptide-38
Skin Conditioning
Acetyl Tetrapeptide-2
Skin Conditioning
Trifluoroacetyl Tripeptide-2
Skin Conditioning
Propanediol
Solvent
Sodium Hyaluronate
Humectant
1,2-Hexanediol
Skin Conditioning
Caprylyl Glycol
Emollient
Hydroxyacetophenone
Antioxidant
Tetrasodium Glutamate Diacetate
Water, Sh-Oligopeptide-1, Sh-Oligopeptide-2, N-Prolyl Palmitoyl Tripeptide-56 Acetate, Sh-Polypeptide-1, Sh-Polypeptide-9, Tetrapeptide-21, Caprooyl Tetrapeptide-3, Acetyl Hexapeptide-8, Acetyl Hexapeptide-38, Palmitoyl Tripeptide-38, Acetyl Tetrapeptide-2, Trifluoroacetyl Tripeptide-2, Propanediol, Sodium Hyaluronate, 1,2-Hexanediol, Caprylyl Glycol, Hydroxyacetophenone, Tetrasodium Glutamate Diacetate
Water
Skin ConditioningAcetyl Hexapeptide-8
Humectant
Pentapeptide-18
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Palmitoyl Tripeptide-38
Skin Conditioning
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Skin Conditioning
Glycerin
Humectant
Ceramide EOP
Skin Conditioning
Ceramide NP
Skin Conditioning
Ceramide AP
Skin Conditioning
Hydrolyzed Collagen
Emollient
Alanine
Masking
Serine
Masking
Valine
MaskingIsoleucine
Skin ConditioningProline
Skin Conditioning
Histidine
Humectant
Phenylalanine
Masking
Arginine
Masking
Aspartic Acid
Masking
Phenoxyethanol
Preservative
Water, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Glycerin, Ceramide EOP, Ceramide NP, Ceramide AP, Hydrolyzed Collagen, Alanine, Serine, Valine, Isoleucine, Proline, Histidine, Phenylalanine, Arginine, Aspartic Acid, Phenoxyethanol
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".
It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.
The comparison to Botox does have limits because the molecule is water-loving and relatively large.
Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.
So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.
A 12 week human study of a multi-ingredient regimen containing this ingredient saw:
While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).
Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.
Learn more about Acetyl Hexapeptide-8This synthetic, signal peptide has unique skin conditioning properties in that is a matrikine-mimetic compound.
First of all, Palmitoyl Tripeptide-38 is a signal peptide; signal peptides tell the body to create more collagen.
What is a matrikine-mimetic compound?
This peptide has the ability to mimic matrikines in skin. Our skin created matrikines by breaking down matrix proteins into peptides.
Matrikines play a role in:
Though further research is needed, this ingredient seems pretty promising. In one study, women over the age of 40 with visible photoaging used a vitamin C serum with this ingredient for 56 days (15% ascorbid acid, 5 ppm palmitoyl tripeptide‐38). The results found improvement in skin roughness and skin tone.
This peptide is also part of the famous Matrixyl synthe’6, a blend of ingredients that also includes glycerin, water, and hydroxypropyl cyclodextrin.
Learn more about Palmitoyl Tripeptide-38Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water
