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Retin-A (Tretinoin) Retin-A (Tretinoin) Cream 0.05% Versus Curology Custom Formula (Tretinoin 0.04% Clindamycin phosphate 1% Azelaic acid 7%)

Prescription
Prescription
South African Brand South Africa
American Brand United States

Updated on January 15, 2024

Overview

What they are

These products are both reef safe prescription. They have a total of 2 ingredients in common

Cool Features

They both contain retinoid

Suited For

They're both likely to be good for fighting acne, anti aging, brightening skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning

Tretinoin is the best retinoid due to its proven skin benefits. It only available with a prescription in many countries.

All retinoids goes through a conversion line until it can become effective. The final step of conversion is retinoic acid; retinoic acid IS Tretinoin.

This is why tretinoin is so effective; it gets to work immediately on the skin.

Research on tretinoin has found it to be incredibly effective for reducing the signs of aging. It helps improve damage from the sun, even the skin tone, and smooth out wrinkles. It is also an effective acne treatment by reducing and balancing out sebum production in pores.

Tretinoin, like other forms of Vitamin A, increases the turnover cycle of skin cells. This helps the skin create newer and healthier skin cells faster.

It can cause irritation, redness, and dry skin because it is considered a "strong" ingredient. Those with sensitive skin should consult a professional about using tretinoin.

Using retinoids will increase sun-sensitivity in the first few weeks of use. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

Read about a form of retinoid you can purchase at the store, retinol.

Learn more about Tretinoin
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

640 Routines
2% use in am
98% use in pm
65% use every day
When to use See routines that use it ->
9 Routines
0% use in am
100% use in pm
78% use every day

Reviews

Here's what our community thinks

Retin-A (Tretinoin) Retin-A (Tretinoin) Cream 0.05% 9 ingredients

4.0 /5
from 2 ratings
Works Well (2) Great Value (1) Heavy (1)
chlolands's avatar

chlolands

1 year ago
Review

Never gave me the miracle results I've seen all over TikTok but served me well for the 3+ years I was on this.

#heavy
#works well
hmmh's avatar

hmmh

1 year ago
Review

Been on this for 4 years. It does not perform miracles but it does keep your skin youthful to some extent sans procedures. Worked on reducing inflammation and acne but dried my skin out, even after a full year of consistent use. With this, sunscreen is non-negotiable.

#great value
#drying
#irritating
#sticky

Curology Custom Formula (Tretinoin 0.04% Clindamycin phosphate 1% Azelaic acid 7%) 12 ingredients

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