Versus

Perrigo Hydroquinone 4% Cream Versus Menarini Tretinoin Gel 0.05%

Facial Treatment
Prescription
American Brand United States
Italian Brand Italy

Updated on April 16, 2025

Overview

Suited For

They're both likely to be good for dry skin and dark spots

Free From

They both do not contain any harsh alcohols, common allergens, fragrances, silicones or sulfates

What's Inside

They both contain oils and parabens

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Humectant, Skin Conditioning, Solvent

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

Another role of this ingredient is preventing a product from melting or freezing. Propylene glycol also adds antimicrobrial properties to a product, elongating product lifespan.

This ingredient is considered an organic alcohol and commonly added into both cosmetics and foods.

Those with sensitive skin or conditions may develop a rash when using this ingredient.

Learn more about Propylene Glycol
Preservative

Propylparaben is a preservative and is a paraben with antifungal and antimicrobial properties.

This ingredient can be naturally found in plants and insects, but most of it is synthetically manufactured for human use. In cosmetics, it is usually created by reacting para-aminobenzoic acid and propanol (an alcohol).

You can usually find this ingredient in water-based products.

Parabens have come under controversy due to the claim they are hormone disruptors. Studies show conflicting results. We recommend speaking with a professional if you have any concerns.

Propylparaben is commonly found in food, medicine, and cosmetics.

Learn more about Propylparaben
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

77 Routines
29% use in am
71% use in pm
87% use every day
When to use See routines that use it ->
241 Routines
1% use in am
99% use in pm
69% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Perrigo Hydroquinone 4% Cream 11 ingredients

Hydroquinone 4% Cream hasn't been rated yet.
Rate it now

Menarini Tretinoin Gel 0.05% 11 ingredients

5.0 /5
from 3 ratings
Drying (1) Great Value (1) Works Well (1)
SailorMoon_954's avatar

SailorMoon_954

1 year ago
Review

help with my acne but drying

m51's avatar

m

20 days ago
Review

It is amazing for acne. I had forehead acne where it was cysts, comedies, fungal acne. It went all away using this. I had deep rooted scarring and hyperpigmentation marks and scars and this helped heal it all. Problem is you can burn yourself if you don’t use it sparingly, in a consistent routine. It also is very very drying so you need to moisture a lot. It also causes ur skin to flake as this Show more

#great value
#drying
#works well