Versus

Galderma Aklief Trifarotene Cream Versus La Roche-Posay Effaclar Adapalene Gel 0.1% Topical Retinoid For Acne

Prescription
Facial Treatment
Swiss Brand
French Brand

Updated on July 05, 2025

Overview

Suited For

They're both likely to be good for dry skin and scar healing

Free From

They both do not contain any common allergens, fragrances, oils or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

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What's inside (and what isn't)

What's inside (and what isn't)

At a glance

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Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Humectant, Skin Conditioning, Solvent

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

Another role of this ingredient is preventing a product from melting or freezing. Propylene glycol also adds antimicrobrial properties to a product, elongating product lifespan.

This ingredient is considered an organic alcohol and commonly added into both cosmetics and foods.

Those with sensitive skin or conditions may develop a rash when using this ingredient.

Learn more about Propylene Glycol
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

191 Routines
4% use in am
96% use in pm
70% use every day
When to use See routines that use it ->
453 Routines
5% use in am
94% use in pm
66% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

3.33
Overall rating
5
4
3
2
1
What people say
Works Well 50% Expensive 50% Drying 50%
4.50
Overall rating
5
4
3
2
1
What people say
Drying 33% Irritating 33% No Scent 33%