DRMTLGY Retinol Complex 0.5% Versus ZO Skin Health Growth Factor Serum
Updated on June 12, 2025
Overview
What they are
These products are both cruelty-free and reef safe serums. They have a total of 5 ingredients in common
Cool Features
They both contain Vitamin E
Suited For
They're both likely to be good for anti aging, dry skin, brightening skin and scar healing
Free From
They both do not contain any harsh alcohols, common allergens, oils or parabens
What's Inside
They both contain silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
DRMTLGY Retinol Complex 0.5% 8 ingredients
ZO Skin Health Growth Factor Serum 34 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
DRMTLGY Retinol Complex 0.5% 8 ingredients
ZO Skin Health Growth Factor Serum 34 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningCyclopentasiloxane
Emollient
Dipropylene Glycol
MaskingPropylene Glycol
Humectant
Dimethicone
Emollient
Glycerin
Humectant
Dimethicone Crosspolymer
Emulsion Stabilising
Dimethicone/PEG-10/15 Crosspolymer
PEG-12 Dimethicone Crosspolymer
EmulsifyingButylene Glycol
Humectant
Dimethicone/Vinyl Dimethicone Crosspolymer
Skin Conditioning
Sodium Phosphate
BufferingPanthenyl Triacetate
Phospholipids
Skin Conditioning
Magnesium Sulfate
Hydrolyzed Sericin
Skin ConditioningEthyl Linoleate
Emollient
Buddleja Davidii Meristem Cell Culture
Skin ConditioningAngelica Polymorpha Sinensis Root Extract
Skin ConditioningDipeptide Diaminobutyroyl Benzylamide Diacetate
Skin Conditioning
Lactobacillus/Panax Ginseng Root Extract Ferment Filtrate
Skin ConditioningDisodium Acetyl Glucosamine Phosphate
Skin ConditioningAcetyl Tyrosine
Skin ConditioningDimethiconol
Emollient
Oleyl Alcohol
Emollient
Proline
Skin ConditioningParfum
Masking
Tocopherol
Antioxidant
Beta-Glucan
Skin Conditioning
Adenosine Triphosphate
Skin ConditioningHydrolyzed Vegetable Protein
Skin ConditioningSodium Chloride
Masking
Xanthan Gum
EmulsifyingPhenoxyethanol
Preservative
Water, Cyclopentasiloxane, Dipropylene Glycol, Propylene Glycol, Dimethicone, Glycerin, Dimethicone Crosspolymer, Dimethicone/PEG-10/15 Crosspolymer, PEG-12 Dimethicone Crosspolymer, Butylene Glycol, Dimethicone/Vinyl Dimethicone Crosspolymer, Sodium Phosphate, Panthenyl Triacetate, Phospholipids, Magnesium Sulfate, Hydrolyzed Sericin, Ethyl Linoleate, Buddleja Davidii Meristem Cell Culture, Angelica Polymorpha Sinensis Root Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Lactobacillus/Panax Ginseng Root Extract Ferment Filtrate, Disodium Acetyl Glucosamine Phosphate, Acetyl Tyrosine, Dimethiconol, Oleyl Alcohol, Proline, Parfum, Tocopherol, Beta-Glucan, Adenosine Triphosphate, Hydrolyzed Vegetable Protein, Sodium Chloride, Xanthan Gum, Phenoxyethanol
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Cyclopentasiloxane, or D5, is a silicone used to improve texture of products and trap moisture.
D5 is considered lightweight and volatile. Volatile means it evaporates quickly after application. Once evaporated, D5 leaves a thin barrier that helps keep skin hydrated.
It is also an emollient. Emollients help soften the skin and prevent water loss. Silicones create a silky texture in products. D5 helps other ingredients become more spreadable.
Studies show D5 is safe to use in skincare products. We recommend speaking with a skincare professional if you have concerns.
Learn more about CyclopentasiloxaneDimethicone Crosspolymer is a silicone created by modifying dimethicone with hydrocarbon side chains. Due to its large size, it does not penetrate skin. It is considered non-occlusive.
Dimethicone Crosspolymer is used to stabilize and thicken products. It also helps give products a silky feel.
This ingredient is a silicone used to improve the texture of products and absorb oil. It does not get absorbed into the skin.
Like other silicones, Dimethicone/Vinyl Dimethicone Crosspolymer helps condition the skin by creating a barrier. In this sense, it can act as an emollient and trap moisture in.
This ingredient is a type of elastomer.
Learn more about Dimethicone/Vinyl Dimethicone CrosspolymerDimethiconol is a silicone that resembles the popular dimethicone. Like other silicones, it is an emollient. Emollients create a thin film on skin to prevent moisture from escaping.
This ingredient helps to create a silky texture and improve spreadability. Due to its high molecular weight and thickness, it is often combined with cyclopentasiloxane.
Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolIngredient Ratings
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When to use
DRMTLGY Retinol Complex 0.5% 8 ingredients
ZO Skin Health Growth Factor Serum 34 ingredients
Reviews
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