Versus

Apostrophe Custom Prescription Versus Curology Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%)

Prescription
Prescription
American Brand United States
American Brand United States

Updated on November 16, 2023

Overview

What they are

These products are both reef safe prescription. They have a total of 2 ingredients in common

Cool Features

They both contain niacinamide

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Smoothing

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Learn more about Niacinamide
Masking, Skin Conditioning

This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride

When to use

32 Routines
9% use in am
91% use in pm
72% use every day
When to use See routines that use it ->
63 Routines
13% use in am
87% use in pm
97% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Apostrophe Custom Prescription 9 ingredients

Custom Prescription hasn't been rated yet.
Rate it now

Curology Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%) 13 ingredients

5.0 /5
from 2 ratings
USAFGal09's avatar

USAFGal09

2 years ago
Review

HOLY GRAIL PRODUCT
The title says it all; this is the one skincare product that I can 110% tell you has made a difference in my skin. I started using it in 2012 and every time I've stopped, I notice the difference. And yes, the difference is visual! I love that it's tailored to you makes it worth the money.