Padagis Estradiol Vaginal Cream USP, 0.01%

Padagis Estradiol Vaginal Cream USP, 0.01%

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Overview

What it is

Prescription with 12 ingredients

Suited For

It has ingredients that are good for dry skin

Free From

It doesn't contain any harsh alcohols, common allergens, oils or silicones

Fun facts

Padagis is from Israel.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

What's inside

Benefits

Concerns

Ingredients Explained

Skin Conditioning

We don't have a description for Estradiol yet.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Solvent

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

Another role of this ingredient is preventing a product from melting or freezing. Propylene glycol also adds antimicrobrial properties to a product, elongating product lifespan.

This ingredient is considered an organic alcohol and commonly added into both cosmetics and foods.

Those with sensitive skin or conditions may develop a rash when using this ingredient.

Learn more about Propylene Glycol
Emollient, Emulsifying, Emulsion Stabilising

Stearyl Alcohol is a type of fatty alcohol from stearic acid. It is a white, waxy compound used to emulsify ingredients.

Fatty Alcohols are most often used as an emollient or to thicken a product. Emollients help soothe and hydrate the skin by trapping moisture.

They are usually derived from natural fats and oils and therefore do not have the same drying or irritating effect as solvent alcohols. FDA allows products labeled "alcohol-free" to have fatty alcohols.

Learn more about Stearyl Alcohol
Emulsion Stabilising

Ceresin is a wax derived from ozokerite. It is an alternative to beeswax.

The most common process of creating ceresin is by using heat and sulfuric acid.

Emulsion Stabilising

This ingredient is a semi-synthetic polymer created from cellulose. In case you need a refresher, cellulose is the main component of plant cell walls.

Hydroxypropyl Methylcellulose has many uses:

  • emulsifier
  • create a gel-like texture
  • boost foam
Cleansing, Emulsifying, Foaming

Sodium Lauryl Sulfate (SLS) is a sulfate with surfactant properties.

The surfactant property make it a great foam creator and cleansing agent. Surfactants help bind ingredients that normally do not mix.

Some studies have shown skin irritation due to prolonged SLS use.

Sodium Laureth Sulfate (SLES) is a milder version of SLS.

Learn more about Sodium Lauryl Sulfate
Preservative

Methylparaben is a preservative and is a paraben. It is used to prevent the growth of fungus, mold, and other harmful bacteria. Parabens are chemicals used as preservatives in both cosmetics and food.

Methylparaben can be synthetically created. It can also be found naturally in some fruits, such as blueberries.

Oftentimes, Methylparaben is combined with other parabens to help increase the shelf life.

The safety of Methylparaben is currently being studied. While ongoing studies are looking into the safety of parabens, the results have been very mixed. Some studies have not found Methylparaben to be harmful.

Learn more about Methylparaben

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA

Tert-Butylhydroquinone Dimethylether is a fragrance.

Emulsifying

Polysorbate 80 is a surfactant and emulsifier. It is used to keep ingredients together, and prevent oils and waters from separating.

It is made from polyethoxylated sorbitan and oleic acid. This ingredient can be found in cosmetics, foods, and medicine. It is water-soluble.

Polysorbate 80 may not be fungal acne safe.

Learn more about Polysorbate 80
Emollient, Emulsifying

Glyceryl Stearate is a mix of glycerin and stearic acid.

It is used to stabilize the mixing of water and oil ingredients. By preventing these ingredients from separating, it can help elongate shelf life. It can also help thicken the product's texture.

As an emollient, it helps soften skin and supports barrier-replenishing ingredients.

In cosmetics, Glyceryl Stearate is often made from vegetable oils or synthetically produced.

This ingredient may not be fungal-acne safe

Fun fact: The human body also creates Glyceryl Stearate naturally.

Learn more about Glyceryl Stearate

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Where it's from

Padagis is a Israeli brand

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Verified by SkinSort

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The data we've presented on this page has been verified by a member of the SkinSort Team.

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ยท Updated September 22, 2025 Added by amydavis4