Garden of Wisdom Pro-Pre Biotic Skin Protectant

This ingredient is more of a microbiome agent rather than an active; it helps rebalance the skin's microbial community.

The bacteria and their metabolites produce lactic acid and other antimicrobial compounds that crowd out the "bad bacteria". Research on Lactobacillus strains shows activity against pathogens and acne-causing bacteria.

One strain, Lactobacillus plantarum, has also been shown to boost collagen synthesis and lower melanin synthesis in lab and clinical observation.

The most eye-catching data comes from acne research, a topical cream with live lactobacilli was well-tolerated and improved skin hydration by 37.3% after 14 days of use and 45.6% after 28 days.

Sources for this ingredient are usually fermented substrates like dairy, soy, or rice.

In general, this is a low-irritation and well-tolerated ingredient that plays nice with most of your routine.

One thing to keep in mind is that live bacteria are hard to keep alive inside of a skincare product. They struggle to survive on the shelf and don't get along with the preservatives that stop products from spoiling.

That's why you'll see ferment and postbiotic forms instead, like Lactobacillus Ferment or Lactobacillus Ferment Lysate.

There isn't a fixed percentage for this ingredient since it is dosed by strain and viable count.

On the fungal acne front: Lactobacillus is a bacterium (not a fungus). The whole culture contains no fatty acids, esters, or oils that Malassezia can feed on so it is considered fungal acne safe.

A 2023 review noted that probiotic fermentation ingredients like this one can enhance antioxidant capacity, reduce UV-induced oxidative damage, and support barrier function.

One clinical study from the same year showed a Lactobacillus ferment lysate significantly reduced transepidermal water loss and improved skin hydration.

Another review highlighted that topical Lactobacillus-based preparations can improve ceramide levels in the stratum corneum, support barrier integrity, and even help reduce S. aureus colonization in atopic dermatitis.

Why is this so cool?

Basically, your skin's outer layer works as a brick wall; skin cells are bricks and ceramides are the mortar holding it together. Moisture escapes, irritants get in, and your skin gets dry and reactive when ceramide levels drop. On top of that, "bad" skin bacteria S. aureus loves to move in when your barrier is weak to make inflammation and irritation worse.

So Lactobacillus ferment is basically patching the wall and evicting the troublemaker when it boosts ceramide production and help keep S. aureus in check.

On top of all this, it also acts as a mild antimicrobial preservative booster.

Just so you know, most studies focus on specific strains or the lysate form rather than this generic "Lactobacillus Ferment", so results can vary.

Though it's a promising ingredient, it doesn't have decades of robust clinical data behind it just yet.

Lactobacillus Ferment is generally considered safe for fungal-acne prone skin. The key thing to understand is that it comes from bacteria, not yeast or fungus.

Yeast-derived ferments (like galactomyces) have been shown to activate a protein that's linked to Malassezia-related skin issues whereas lactobacillus doesn't have that problem.

Its byproducts also don't contain the types of fatty acids (C11-24 chain lengths) that Malassezia feeds on.

Early studies suggest it may also help reduce hyperpigmentation by interrupting certain skin processes but more research is needed.

Vitamin C contains many skin benefits.

A 2023 study found blueberries to protect skin from UV-B related inflammation. However, this ingredient should not replace your sunscreen.

It also contains other goodies, such as Vitamin C, beta-carotene, glutathione, and Vitamin E.

Beet root has many benefits when eaten. More research is needed on applying beetroot in skincare.

Beet Root is used to add pink/red color.

Beta-carotene is the reason we turn orange if we eat too many carrots.

It should be noted coming into contact with the leaves of wild carrots can cause skin irritation. The sap causes phytophotodermatitis, or sensitivity exposed to sunlight.

This ingredient is created using the edible parts of the carrot.

Broccoli is also rich in fatty acids such as oleic and linoleic acids.

Brassica Oleracea Italica Extract can be extracted from any part of the broccoli plant.

Kale leaf extract also helps hydrate the skin as a humectant. Kale is rich in omega-3 and omega-6 fatty acids that help soothe and hydrate skin. Studies show Brassica Oleracea Acephala Leaf Extract is effective at calming inflammation and treating inflammatory skin diseases.

Besides Vitamin C, Kale is also rich in vitamin A and vitamin K.

The antioxidant activity comes from its flavonoid, polyphenol, and sterol content.

Studies show low concentrations of this ingredient did not cause skin irritation:

Capsicum Frutescens Fruit Extract is often used in the same studies due to their similarities. However, a study found Capsicum Annuum to have higher antibacterial activity.

Another study found Capsicum Annuum to absorb a tiny bit of UV, but this should not replace your sunscreen.

Another study from 2025 found that cabbage leaf extract strong tyrosinase inhibition comparable to vitamin C.

Overall, this is a great supportive ingredient. Be sure to patch test if you have a known allergy to plants in the Brassicaceae family (broccoli, kale, cauliflower).

Cucumbers have anti-aging, anti-inflammatory, and hydrating properties.

The antioxidant properties help protect your body from free-radicals. Free-radicals are molecules that may damage your skin cells. As a result, ginger may help slow down signs of aging such as hyperpigmentation and wrinkles.

Studies show ginger inhibits the enzyme that breaks down collagen. It also helps with:

This ingredient has no negative side-effects and is safe to use unless one has a specific allergy to it.

Ginger originates from Southeast Asia but has spread throughout the world. It is now a common spice used in many cultures.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.