Bioderma Sensibio Tolerance+
A moisturizer with 15 ingredients, including exfoliants and peptides.
Overview
What it is
General moisturizer with 15 ingredients that contains exfoliants and peptides
Cool Features
It is reef safe
Suited For
It has ingredients that are good for dry skin, sensitive skin, oily skin, reducing pores and scar healing
Free From
It doesn't contain any harsh alcohols, common allergens, fragrances, oils, parabens, silicones or sulfates
Fun facts
Bioderma is from France. This product is used in 3 routines created by our community.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterIsostearyl Isostearate is a plant-based and vegan emollient ester made by reacting Isostearyl Alcohol and Isostearic Acid.
It helps improve how the product spreads on skin, acts as a binding agent for makeup powders without modifying pigment color, and softens skin while helping it hold onto water.
This ingredient is very interesting as a hydrator; most moisturizers are either occlusives, humectants, or emollients. Isostearyl isostearate works through another route named "internal occlusion" by the head researcher.
Isostearyl isostearate nudges the skin's own lipids into a denser, more tightly packed arrangement. Packing the deeper layers of the stratum corneum together more efficiently means less water is able to escape.
This is a barrier-improving mechanism that hadn't been described before and plastic occlusion stress tests confirmed it improved the skin's water-permeability barrier function
Just one thing worth noting from the same review: this ingredient increased the penetration rate of a test drug through excised human skin. Though this ingredient is not classified as a penetration enhancer, it does interact with the barrier rather than sitting totally inert on top.
Fungal acne:
The Malassezia yeast feeds on fatty acids and esters in the C11-24 range. Since both halves of this molecules are C18, it may not be fungal acne safe.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinSilica, also known as silicon dioxide, is a naturally occurring mineral. It is used as a fine, spherical, and porous powder in cosmetics.
Though it has exfoliant properties, the function of silica varies depending on the product.
The unique structure of silica enhances the spreadability and adds smoothness, making it a great texture enhancer.
It is also used as an active carrier, emulsifier, and mattifier due to its ability to absorb excess oil.
In some products, tiny microneedles called spicules are made from silica or hydrolyzed sponge. When you rub them in, they lightly polish away dead skin layers and enhance the penetration of active ingredients.
Learn more about SilicaGlyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
Learn more about Glyceryl StearateSodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.
Its main functions are to maintain the pH of a product and neutralize metal ions.
The acidity of our skin is maintained by our glands and skin biome; normal pH level of skin is slightly acidic (~4.75-5.5).
Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.
Learn more about Sodium CitrateCapryloyl Glycine is created by adding an acyl group to glycine and caprylic acid chloride.
It is a cleanser due to its surfactant properties. Surfactants help dirt, oil, and other polluants be more easily rinsed away. According to manufacturers, Capryloyl Glycine also helps soften the skin and regulate sebum production.
Emerging studies show Capryloyl Glycine may inhibit hair growth. It may also cause allergies for some people. We recommend speaking with a professional if you have any questions about this ingredient.
Learn more about Capryloyl GlycineMannitol is a sugar alcohol. It is a humectant and moisturizes the skin. In vitro (not tested on a living organism), mannitol displays antioxidant properties.
When found in aqueous solutions, mannitol tends to become acidic. This is because it loses a hydrogen ion. This is why mannitol can often be found with pH adjusting ingredients, such as sodium bicarbonate.
Fun fact: Mannitol can be found in foods as a sweetener. It can be naturally found in mushrooms, algae, fruits, and veggies.
Learn more about MannitolXylitol is a humectant and prebiotic. It can help with dry skin.
In studies, xylitol has been shown to improve dry skin. It decreased transepidermal water loss, or when water passes through the skin and evaporates. Xylitol also showed to help improve the biomechanical properties of the skin barrier.
The prebiotic property of xylitol may also help reinforce our skin's natural microbiome. Having a healthy microbiome prevents infection by bad bacteria and helps with hydration.
As a humectant, Xylitol helps draw moisture from both the air and from deeper skin layers. This helps keep skin hydrated.
Xylitol is a sugar alcohol and commonly used as a sugar substitute. It is naturally occurring in plants such as strawberries and pumpkin.
Learn more about XylitolWe don't have a description for Rhamnose yet.
Sodium PCA is the sodium salt of pyroglutamic acid. It is naturally occurring in our skin's natural moisturizing factors where it works to maintain hydration.
The PCA stands for pyrrolidone carboxylic acid, a natural amino acid derivative.
This ingredient has skin conditioning, anti-inflammatory, and humectant properties. Humectants help hydrate your skin by drawing moisture from the air. This helps keep your skin moisturized.
Learn more about Sodium PCAAcetyl Tetrapeptide-15 is a peptide.
We don't have a description for Undecylenoyl Glycine yet.
We don't have a description for Dehydroxanthan Gum yet.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideReviews
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Where it's from
Bioderma is a French brand
Often compared with
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated September 7, 2025 • Added by sandrasantos
