Overview
What it is
Serum with 11 ingredients that contains Vitamin E
Cool Features
It is vegan, cruelty-free, and reef safe
Suited For
It has ingredients that are good for anti aging, dry skin, brightening skin, sensitive skin, scar healing and dark spots
Free From
It doesn't contain any harsh alcohols, common allergens, parabens, silicones or sulfates
Fun facts
4.5.6 is from France.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside (and what isn't)
Ingredients List
Dive into the full list of ingredients.
Key Ingredients
Benefits
Concerns
Ingredients Explained
Heptyl Undecylenate isn't fungal acne safe.
This ingredient is a solvent, texture enhancer, and emollient.
Solvents help other ingredients dissolve in a product. It adds a 'silky' texture to products and is thus considered a silicone alternative.
This ingredient feeds fungal-acne due to its 13-16 carbon chain.
Learn more about C13-16 IsoparaffinCannabis Sativa Seed Oil is the fixed oil expressed from the seeds of the Cannabis sativa plant. This is also known as hemp oil.
Hemp oil is an emollient and nourishes the skin. It contains many fatty acids such as linoleic acid, amino acids, phospholipids, and vitamin E.
The difference between hemp and cannabis is their psychoactive component. Hemp has low amounts of THC.
Learn more about Cannabis Sativa Seed OilOlea Europaea Fruit Oil is the fixed oil obtained from the ripe fruit of the Olive. In other words - olive oil.
The primary contents of olive oil are glycerides of the fatty acids linoleic, oleic and palmitic.
Olive oil also contains antioxidants such as Vitamin E. Antioxidants may help reduce signs of aging by fighting unstable free-radical molecules. It also contains Vitamins A (retinol), D, and K.
The squalene in olive oil makes it a great emollient. Emollients help soothe and soften your skin by trapping moisture in. This makes olive oil a great skin moisturizer.
Studies show olive oil to have antibacterial and antifungal properties in low concentrations. Another study found olive oil irritated sensitive oily skin. We always recommend speaking with a professional about using this ingredient in your routine.
Due to the fatty acid content, this ingredient may not be fungal-acne safe.
Learn more about Olea Europaea Fruit OilNigella Sativa Seed Oil is a fragrance and is an oil.
Another popular name for this ingredient is Synovea HR. This ingredient is a skin lightener and antioxidant.
Like other skin lighteners, it blocks the process of skin darkening. Specifically, this ingredient blocks tyrosinase, the enzyme responsible for darkening skin when exposed to UV.
Hexylresorcinol works well with other ingredients. Studies show this ingredient boosts the effect of niacinamide, various forms of vitamin C, and retinoids.
Many consider this to be a safer alternative to hydroquinone. In fact, this ingredient produces the same results as hydroquinone in lower amounts.
Fun fact: This ingredient can also be found food and medicine for treating skin infections.
Gentle reminder from SkinSort: all skin tones are beautiful!
Learn more about HexylresorcinolBakuchiol is a plant-derived antioxidant (it's vegan!). It is often called the replacement for retinol although it is not part of the same family.
It has similar effects as retinol: skin smoothing, reducing discoloration, and preventing wrinkles. It does not cause as much irritation as traditional retinoids.
Bakuchiol works by breaking down free radicals and stimulating collagen production in skin.
Combining bakuchiol with retinol will not have adverse side effects. Studies show using them will just boost the benefits. Bakuchiol is also found to help stabilize retinol.
While bakuchiol does not make the skin more sun sensitive, we recommend wearing SPF on a daily basis.
Read more about traditional retinol
Learn more about BakuchiolTocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolUbiquinone (Coenzyme Q10) is a molecule already found in our bodies. It is a potent antioxidant and skin-soothing ingredient.
Aging and environmental exposure diminishes our skin's natural ubiquinone levels. This is much like our natural collagen and elastin.
The good news is: studies show applying this ingredient topically replenishes ubiquinone levels in our skin. This also comes with a ton of skin benefits. These benefits include:
Ubiquinone is considered a large molecule and cannot be absorbed into the lower layers of skin. This is why it is believed to be such an effective antioxidant: it protects our skin in the upper layers and prevents damage in the deeper layers.
When used in sunscreen, ubiquinone is shown to increase ingredient stability, increase SPF factor, and add to infrared protection.
Fun fact: ubiquinone is fat-soluble.
Learn more about UbiquinoneMelia Azadirachta Seed Oil is an oil and isn't fungal acne safe.
Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumReviews
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Where it's from
4.5.6 is a French brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated February 4, 2025 • Added by nicolemlln