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Product Comparison

Here's our complete breakdown comparing the ingredients, attributes, and more of Apostrophe Azelaic Acid 20% Prescription versus Curology Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%) .

Last updated on November 16, 2023. Published on December 31, 2021

Overview

What they are

These products are both reef safe prescription. They have a total of 9 ingredients in common

Cool Features

They both contain Vitamin E

Suited For

They're both likely to be good for fighting acne, brightening skin, sensitive skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, common allergens, oils, parabens, silicones or sulfates

What's Inside

They both contain fragrances

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that need an update? Let us know.

Prescription American Brand United States
Prescription American Brand United States

Prescription

Prescription skincare treatments. The ingredients in these product are prescription strength and considered medication. In many countries, these must be prescribed by a certified professional.

Prescription

Prescription skincare treatments. The ingredients in these product are prescription strength and considered medication. In many countries, these must be prescribed by a certified professional.

Price

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Buy Azelaic Acid 20% Prescription

Shop

Buy Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%)

Ingredient Info

Click any item below to learn more and view relevant ingredients.
alcohol-free
silicon-free
fragrance-free
sulfate-free
paraben-free
oil-free
fungal-acne safe
reef-safe
eu-allergen-free
vegan
cruelty-free
alcohol-free
silicon-free
fragrance-free
sulfate-free
paraben-free
oil-free
fungal-acne safe
reef-safe
eu-allergen-free
vegan
cruelty-free

At a glance

Click on any of the items below to learn more

Notable Ingredients

Vitamin E

Benefits

Redness Reducing (2)
Reduces Irritation
Reduces Large Pores
Dark Spots
Scar Healing
Acne Fighting
Brightening

Concerns

May Worsen Oily Skin

Notable Ingredients

Vitamin E
Niacinamide

Benefits

Good For Oily Skin
Redness Reducing (3)
Reduces Irritation
Reduces Large Pores (2)
Dark Spots (2)
Scar Healing
Acne Fighting (2)
Brightening (2)

Concerns

May Worsen Oily Skin
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Ingredients Compared

Ingredients that are highlighted in purple are present in both products.

Ingredients Side-by-side

Ingredients that are highlighted in purple are present in both products.

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Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1
What it does: Buffering, Masking
Community Rating: Loved

Azelaic acid is a naturally occurring acid that is derived from grains. However, the lab-created form is typically used within cosmetic products as it has better shelf-stability.

It has been shown to be effective in the treatment of acne, rosacea, and other skin conditions. Azelaic acid helps reduce the growth of bacteria that cause acne and helps to reduce inflammation.

It also helps to improve the appearance of skin by reducing the production of sebum and unclogging pores.

Azelaic Acid also has antioxidant properties. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.

One of the main benefits of azelaic acid is that it is gentle and well-tolerated by most people. It is also non-comedogenic, meaning that it will not clog pores.

Learn more about Azelaic Acid

Apostrophe Azelaic Acid 20% Prescription contains this as ingredient number 1.

Curology Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%) contains this as ingredient number 3.

2
What it does: Skin Conditioning
Community Rating: Liked

Aloe Barbadensis Leaf Juice comes from leaves of the aloe plant. Aloe Barbadensis Leaf Juice is best known for helping to soothe sunburns. It is also anti-inflammatory, moisturizing, antiseptic, and can help heal wounds.

Aloe is packed with good stuff including Vitamins A, C, and E. These vitamins are antioxidants, which help fight free-radicals and the damage they may cause. Free-radicals are molecules that may damage your skin cells, such as pollution.

Aloe Barbadensis Leaf Juice also contains sugars. These sugars come in the form of monosaccharides and polysaccharides, folic acid, and choline. These sugars are able to help bind moisture to skin.

It also contains minerals such as calcium, 12 anthraquinones, fatty acids, amino acids, and Vitamin B12.

Learn more about Aloe Barbadensis Leaf Juice

Apostrophe Azelaic Acid 20% Prescription contains this as ingredient number 2.

Curology Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%) contains this as ingredient number 4.

3
What it does: Emollient, Solvent
Community Rating: Very Disliked

C13-14 Isoparaffin is created from petroleum-based mineral oils. It is an emollient and helps thicken a product.

As an emollient, it helps keep the skin soft and smooth by creating a barrier on top. This barrier traps moisture in, keeping the skin hydrated.

C13-14 Isoparaffin may not be fungal-acne safe.

Learn more about C13-14 Isoparaffin

Apostrophe Azelaic Acid 20% Prescription contains this as ingredient number 3.

Curology Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%) contains this as ingredient number 5.

4
What it does: Skin Conditioning, Solvent
Community Rating: Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. Talk about multi-purpose! If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

Apostrophe Azelaic Acid 20% Prescription contains this as ingredient number 5.

Curology Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%) contains this as ingredient number 7.

5
What it does: Emulsifying
Community Rating: Very Disliked

Laureth-7 is created by the ethoxylation of lauryl alcohol using ethylene oxide. Lauryl alcohol is a fatty alcohol with hydrating properties.

Laureth-7 is an emulsifier and cleansing ingredient. As an emulsifier, it is used to prevent ingredients from separating. It also helps cleanse the skin by gathering dirt, oil, and pollutants to be rinsed away.

Apostrophe Azelaic Acid 20% Prescription contains this as ingredient number 6.

Curology Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%) contains this as ingredient number 8.

6
What it does: Preservative
Community Rating: Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Apostrophe Azelaic Acid 20% Prescription contains this as ingredient number 7.

Curology Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%) contains this as ingredient number 10.

7
What it does:
Community Rating: Disliked

Polyacrylamide is a synthetic polymer. It is used to stabilize products and bind ingredients. When hydrated, Polyacrylamide forms a soft gel.

Polyacrylamide is low-toxicity. If source properly, it is deemed safe to use in cosmetics.

It should be noted the precursor to Polyacrylamide is acrylamide. Acrylamide is a carcinogen. Most reputable sources of Polyacrylamide will screen for residual acrylamide to make sure the count is in a safe range. Acrylamide is not able to be absorbed through the skin.

We recommend speaking with a professional if you have concerns.

Learn more about Polyacrylamide

Apostrophe Azelaic Acid 20% Prescription contains this as ingredient number 8.

Curology Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%) contains this as ingredient number 11.

8
What it does: Antioxidant, Skin Conditioning
Community Rating: Liked

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate

Apostrophe Azelaic Acid 20% Prescription contains this as ingredient number 9.

Curology Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%) contains this as ingredient number 12.

9
What it does: Masking, Perfuming

Triethylene Glycol is a fragrance.

Apostrophe Azelaic Acid 20% Prescription contains this as ingredient number 10.

Curology Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%) contains this as ingredient number 13.

Here's what our community thinks of the ingredients in these two products.

40% are loved or liked
10% have mixed ratings
40% are disliked or very disliked
10% have no rating yet
54% are loved or liked
8% have mixed ratings
31% are disliked or very disliked
8% have no rating yet

Usage

Here's some more info on how this product is used by our community.

When to use

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Reviews

Here's what our community thinks

Apostrophe Azelaic Acid 20% Prescription 10 ingredients

Azelaic Acid 20% Prescription hasn't been rated yet.
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Curology Custom Serum (Niacinamide 4%, Clindamycin 1%, Azelaic 4%) 13 ingredients

5.0 /5
from 2 ratings
USAFGal09's avatar

USAFGal09

1 year ago · Oily Skin
Review

HOLY GRAIL PRODUCT
The title says it all; this is the one skincare product that I can 110% tell you has made a difference in my skin. I started...

HOLY GRAIL PRODUCT
The title says it all; this is the one skincare product that I can 110% tell you has made a difference in my skin. I started using it in 2012 and every time I've stopped, I notice the difference. And yes, the difference is visual! I love that it's tailored to you makes it worth the money.

ttayitsmylife's avatar

ttayitsmylife

1 year ago · Combination Skin
Review

Because it has Tret in it.

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